{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:38:05Z","timestamp":1762508285406},"reference-count":30,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"Supl. 2","license":[{"start":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T00:00:00Z","timestamp":1604016000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["biomedica"],"abstract":"<jats:p>Introducci\u00f3n. La pandemia de COVID-19 ha ocasionado cerca de 25 millones de casos en el mundo. Se ha descrito que los pacientes asintom\u00e1ticos pueden ser fuentes de transmisi\u00f3n. Sin embargo, es dif\u00edcil detectarlos y no es claro su papel en la din\u00e1mica de transmisi\u00f3n del virus, lo que obstaculiza la implementaci\u00f3n de estrategias para la prevenci\u00f3n.Objetivo. Describir el comportamiento de la infecci\u00f3n asintom\u00e1tica por SARS-CoV-2 en una cohorte de trabajadores del Aeropuerto Internacional El Dorado \u201cLuis Carlos Gal\u00e1n Sarmiento\u201d de Bogot\u00e1, Colombia.Materiales y m\u00e9todos. Se dise\u00f1\u00f3 una cohorte prospectiva de trabajadores del Aeropuerto El Dorado. El seguimiento se inici\u00f3 en junio de 2020 con una encuesta a cada trabajador para caracterizar sus condiciones de salud y trabajo. Cada 21 d\u00edas se tom\u00f3 una muestra de hisopado nasofar\u00edngeo para detectar la presencia del SARS-CoV-2 mediante reacci\u00f3n en cadena de la polimerasa con transcriptasa inversa (RT-PCR). Se analiz\u00f3 el comportamiento del umbral del ciclo (cycle threshold) de los genes ORF1ab y N seg\u00fan el d\u00eda de seguimiento. Resultados. En los primeros tres seguimientos de la cohorte se encontr\u00f3 una incidencia de la infecci\u00f3n por SARS-CoV-2 del 16,51 %. La proporci\u00f3n de contactos positivos fue del 14,08 %. La mediana del umbral del ciclo fue de 33,53.Conclusi\u00f3n. Se determinaron las caracter\u00edsticas de la infecci\u00f3n asintom\u00e1tica por el SARSCoV-2 en una cohorte de trabajadores. La detecci\u00f3n de infectados asintom\u00e1ticos sigue siendo un reto para los sistemas de vigilancia epidemiol\u00f3gica.<\/jats:p>","DOI":"10.7705\/biomedica.5802","type":"journal-article","created":{"date-parts":[[2020,11,3]],"date-time":"2020-11-03T13:41:36Z","timestamp":1604410896000},"page":"166-172","update-policy":"http:\/\/dx.doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":9,"title":["SARS-CoV-2 y RT-PCR en pacientes asintom\u00e1ticos: resultados de una cohorte de trabajadores del Aeropuerto Internacional El Dorado de Bogot\u00e1, 2020"],"prefix":"10.7705","volume":"40","author":[{"given":"Jeadran","family":"Malag\u00f3n-Rojas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"G\u00f3mez-Rend\u00f3n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eliana L.","family":"Parra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Almentero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth","family":"Palma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald","family":"L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yesith Guillermo","family":"Toloza-P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivian","family":"Rubio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan Felipe","family":"Bedoya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"L\u00f3pez-D\u00edaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Franco-Mu\u00f1oz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jhonnatan","family":"Reales-Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcela","family":"Mercado-Reyes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4444","published-online":{"date-parts":[[2020,10,30]]},"reference":[{"key":"101260","unstructured":"World Health Organization. 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