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Esta pandemia surgi\u00f3 durante la era de la epidemiolog\u00eda gen\u00f3mica impulsada por los continuos avances en la secuenciaci\u00f3n de pr\u00f3xima generaci\u00f3n. Desde su reciente aparici\u00f3n, la epidemiolog\u00eda gen\u00f3mica permiti\u00f3 la identificaci\u00f3n precisa de nuevos linajes o especies de agentes pat\u00f3genos y la reconstrucci\u00f3n de su variabilidad gen\u00e9tica en tiempo real, lo que se hizo evidente en los brotes de influenza H1N1, MERS y SARS. Sin embargo, la escala global y descontrolada de esta pandemia ha generado una situaci\u00f3n que oblig\u00f3 a utilizar de forma masiva herramientas de la epidemiolog\u00eda gen\u00f3mica como la r\u00e1pida identificaci\u00f3n del SARS-CoV-2 y el registro de nuevos linajes y su vigilancia activa en todo el mundo. Antes de la pandemia de COVID-19 la disponibilidad e datos gen\u00f3micos de agentes pat\u00f3genos circulantes en varios pa\u00edses de Latinoam\u00e9rica y el Caribe era escasa o nula. Con la llegada del SARS-CoV-2 dicha situaci\u00f3n cambi\u00f3 significativamente, aunque la cantidad de informaci\u00f3n disponible sigue siendo escasa y, en pa\u00edses como Colombia, Brasil, Argentina y Chile, la informaci\u00f3n gen\u00f3mica del SARS-CoV-2 provino principalmente de grupos de investigaci\u00f3n en epidemiolog\u00eda gen\u00f3mica m\u00e1s que como producto de una pol\u00edtica o programa de vigilancia en salud p\u00fablica.<\/jats:p>","DOI":"10.7705\/biomedica.5841","type":"journal-article","created":{"date-parts":[[2020,11,3]],"date-time":"2020-11-03T13:41:36Z","timestamp":1604410896000},"page":"188-197","update-policy":"https:\/\/doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":6,"title":["Secuenciaci\u00f3n del SARS-CoV-2: la iniciativa tecnol\u00f3gica para fortalecer los sistemas de alerta temprana ante emergencias de salud p\u00fablica en Latinoam\u00e9rica y el Caribe"],"prefix":"10.7705","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6534-0079","authenticated-orcid":false,"given":"Diego A.","family":"\u00c1lvarez-D\u00edaz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1383-3127","authenticated-orcid":false,"given":"Katherine","family":"Laiton-Donato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3140-8167","authenticated-orcid":false,"given":"Carlos","family":"Franco-Mu\u00f1oz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3721-3176","authenticated-orcid":false,"given":"Marcela","family":"Mercado-Reyes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4444","published-online":{"date-parts":[[2020,10,30]]},"reference":[{"key":"101395","doi-asserted-by":"crossref","unstructured":"Dong E, Du H, Gardner L. 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