{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T21:33:37Z","timestamp":1747258417631},"reference-count":17,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"2","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["biomedica"],"abstract":"<jats:p>Introducci\u00f3n. En los \u00faltimos a\u00f1os ha aumentado la malaria importada en ni\u00f1os, en quienes la enfermedad es potencialmente grave y mortal.Objetivo. Describir la incidencia y caracter\u00edsticas cl\u00ednico-epidemiol\u00f3gicas de ni\u00f1os con diagn\u00f3stico de conmalaria en Alicante, Espa\u00f1a, en los \u00faltimos a\u00f1os.Materiales y m\u00e9todos. Se hizo un estudio observacional y retrospectivo de los casos de malaria en menores de 15 a\u00f1os, diagnosticados en el Hospital General Universitario de Alicante desde 1994 hasta 2019.Resultados. Se registraron 24 casos. El n\u00famero de casos pas\u00f3 de dos en el primer quinquenio a 11 en el \u00faltimo. La mediana de edad fue de 6 a\u00f1os (rango intercuart\u00edlico: 3 a 8). El 91,6 % proced\u00eda de \u00c1frica subsahariana. Los ni\u00f1os nacidos en Espa\u00f1a de padres inmigrantes que viajan a una zona end\u00e9mica para visitar a familiares y amigos (Visiting Friends and Relatives) representaron el 62,5 % (n=15) y solo consta que recibiera quimioprofilaxis antipal\u00fadica un paciente (6,7 %). Los signos cl\u00ednicos m\u00e1s frecuentes fueron fiebre (86,9 %), hepatoesplenomegalia (70,8 %) y anemia (70,8 %). Plasmodium falciparum fue la especie m\u00e1s frecuentemente identificada (83,3 %; n=20). El tratamiento m\u00e1s empleado fue la combinaci\u00f3n de dihidroartemisina y piperaquina por v\u00eda oral (41,6 %, n=10), con evoluci\u00f3n favorable en todos los casos.Conclusiones. Los casos de paludismo infantil importado est\u00e1n aumentando en los \u00faltimos a\u00f1os. Las manifestaciones cl\u00ednicas son inespec\u00edficas en estos ni\u00f1os, por lo que es importante que los profesionales conozcan la enfermedad y tengan un alto \u00edndice de sospecha para iniciar el tratamiento precoz. Adem\u00e1s, deben tomarse las medidas preventivas adecuadas antes de un viaje.<\/jats:p>","DOI":"10.7705\/biomedica.6068","type":"journal-article","created":{"date-parts":[[2022,7,13]],"date-time":"2022-07-13T17:01:11Z","timestamp":1657731671000},"page":"244-252","update-policy":"http:\/\/dx.doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":1,"title":["Malaria importada en poblaci\u00f3n pedi\u00e1trica de Alicante, Espa\u00f1a (1994-2019)"],"prefix":"10.7705","volume":"42","author":[{"given":"Ana Elena","family":"Pascua-Santamar\u00eda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Torr\u00fas-Tendero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gema","family":"Mira-Perceval","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paloma","family":"Garc\u00eda-Gal\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Manuel","family":"Ramos-Rinc\u00f3n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4444","published-online":{"date-parts":[[2022,6,1]]},"reference":[{"key":"108880","unstructured":"World Health Organization. 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