{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T07:09:49Z","timestamp":1769152189912,"version":"3.49.0"},"reference-count":40,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"1","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["biomedica"],"abstract":"<jats:p>Introducci\u00f3n. En Per\u00fa, la microscop\u00eda \u00f3ptica con gota gruesa contin\u00faa utiliz\u00e1ndose en el seguimiento de los pacientes con malaria o paludismo. Esta prueba es sencilla, pero requiere de equipamiento microsc\u00f3pico y personal id\u00f3neo que realice la lectura de las muestras. Los estudios sugieren que la prueba r\u00e1pida OptiMAL-IT\u2122 es una opci\u00f3n para dicho seguimiento.Objetivo. Evaluar la efectividad de OptiMAL-IT\u2122 como test de seguimiento en pacientes con malaria en \u00e1reas end\u00e9micas del Per\u00fa.Materiales y m\u00e9todos. Se hizo un estudio observacional, transversal y anal\u00edtico de pruebas diagn\u00f3sticas en pacientes con malaria. Se seleccion\u00f3 a todos los pacientes que cumpl\u00edan con los criterios de inclusi\u00f3n, procedentes de diferentes establecimientos de salud de los departamentos peruanos de San Mart\u00edn y Loreto. El diagn\u00f3stico se hizo mediante microscop\u00eda \u00f3ptica con gota gruesa y la prueba r\u00e1pida de diagn\u00f3stico inmunocromatogr\u00e1fico OptiMAL-IT\u2122 en los d\u00edas 2, 3, 7 y 14 para Plasmodium vivax y hasta el d\u00eda 21 de seguimiento para Plasmodium falciparum. Se calcul\u00f3 el porcentaje de los correctamente clasificados y los valores predictivos, y se compararon los resultados de la selva occidental y la selva oriental mediante ji al cuadrado o prueba exacta de Fisher. Resultados. Se registraron 262 pacientes de San Mart\u00edn y 302 de Loreto. Los porcentajes correctamente clasificados y el valor predictivo negativo fueron superiores a 92,0 y 93,0 %, respectivamente, a partir del tercer d\u00eda de seguimiento; no se encontraron diferencias estad\u00edsticas en los resultados obtenidos en la Amazon\u00eda occidental y los de la oriental. Conclusiones. La prueba OptiMAL-IT\u2122 ser\u00eda efectiva como test de seguimiento en los pacientes con diagn\u00f3stico de malaria en \u00e1reas end\u00e9micas del Per\u00fa.<\/jats:p>","DOI":"10.7705\/biomedica.6079","type":"journal-article","created":{"date-parts":[[2022,4,7]],"date-time":"2022-04-07T14:31:13Z","timestamp":1649341873000},"page":"147-158","update-policy":"https:\/\/doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":1,"title":["Evaluaci\u00f3n de la efectividad de la prueba r\u00e1pida OptiMAL-IT\u2122 para el seguimiento de pacientes con diagn\u00f3stico de malaria en la Amazon\u00eda peruana"],"prefix":"10.7705","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5031-5850","authenticated-orcid":false,"given":"Nancy","family":"Arr\u00f3spide","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0838-4064","authenticated-orcid":false,"given":"Hern\u00e1n","family":"Sanabria","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5588-6860","authenticated-orcid":false,"given":"William J.","family":"Araujo-Banchon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4444","published-online":{"date-parts":[[2022,3,1]]},"reference":[{"key":"107865","unstructured":"Organizaci\u00f3n Mundial de la Salud. 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