{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T08:37:35Z","timestamp":1771058255098,"version":"3.50.1"},"reference-count":26,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"3","license":[{"start":{"date-parts":[[2022,9,2]],"date-time":"2022-09-02T00:00:00Z","timestamp":1662076800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100003402","name":"Fundaci\u00f3n Valle del Lili","doi-asserted-by":"publisher","award":["N.A"],"award-info":[{"award-number":["N.A"]}],"id":[{"id":"10.13039\/501100003402","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["biomedica"],"abstract":"<jats:p>Introducci\u00f3n. El trasplante de c\u00e9lulas madre hematopoy\u00e9ticas es la opci\u00f3n curativa para algunas enfermedades y est\u00e1 aumentando el tiempo de supervivencia de los pacientes. La calidad de vida relacionada con la salud en estos pacientes no se eval\u00faa de manera sistem\u00e1tica.Objetivos. Describir la calidad de vida relacionada con la salud y las complicaciones en ni\u00f1os con trasplante de c\u00e9lulas madre hematopoy\u00e9ticas.Materiales y m\u00e9todos. Es un estudio transversal en pacientes pedi\u00e1tricos sobrevivientes al trasplante. Se midi\u00f3 la calidad de vida relacionada con la salud, utilizando el cuestionario KIDSCREEN-27 en pacientes entre 8 y 14 a\u00f1os y la SF-12\u2122 (Short Form-12) en pacientes mayores de 14 a\u00f1os. El an\u00e1lisis estad\u00edstico se realiz\u00f3 en el software Stata 12. Utilizamos el modelo de Rasch, trasladando estimaci\u00f3n de par\u00e1metros a valores t para obtener el resultado de los cuestionarios.Resultados. En total, 42 pacientes respondieron alguno de los cuestionarios. Los eventos adversos m\u00e1s frecuentes fueron \u201cenfermedad cr\u00f3nica de injerto Vs. contra hu\u00e9sped\u201d y \u201ccomplicaciones endocrinas\u201d. De acuerdo con la normalidad de datos del KIDSCREEN-27, los puntajes de las dimensiones \u201cambiente escolar\u201d y \u201csoporte social y pares\u201d fueron inferiores al percentil 50. En el cuestionario SF-12\u2122, el grupo que utilizaba inmunosupresores tuvo un menor puntaje en el componente f\u00edsico.Conclusiones. En general, los resultados del KIDSCREEN-27 sugieren un cierto d\u00e9ficit de calidad de vida en pacientes entre 8 y 14 a\u00f1os. Los cuestionarios mostraron confiabilidad en la muestra.<\/jats:p>","DOI":"10.7705\/biomedica.6403","type":"journal-article","created":{"date-parts":[[2022,9,19]],"date-time":"2022-09-19T19:09:32Z","timestamp":1663614572000},"page":"531-540","update-policy":"https:\/\/doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":3,"title":["Impacto de la calidad de vida relacionada a la salud en pacientes pedi\u00e1tricos con trasplante de progenitores hematopoy\u00e9ticos en una instituci\u00f3n colombiana"],"prefix":"10.7705","volume":"42","author":[{"given":"Diego","family":"Medina-Valencia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandro","family":"Castillo-Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Estefan\u00eda","family":"Beltr\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eliana","family":"Manzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amparo","family":"Chantre-Mostacilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gloria Piedad","family":"Guerrero-Fajardo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayra","family":"Estacio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexis A.","family":"Franco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4444","published-online":{"date-parts":[[2022,9,2]]},"reference":[{"key":"109975","doi-asserted-by":"crossref","unstructured":"Berbis J, Michel G, Chastagner P, Sirvent N, Demeocq F, Plantaz D, et al. 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