{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T20:52:40Z","timestamp":1773867160479,"version":"3.50.1"},"reference-count":28,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"Sp. 1","license":[{"start":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T00:00:00Z","timestamp":1693440000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T00:00:00Z","timestamp":1693440000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["Biomed."],"abstract":"<jats:p>La fungemia por Geotrichum spp. es poco frecuente y altamente letal. En el Instituto Nacional de Cancerolog\u00eda de Bogot\u00e1 solo se han reportado dos casos: uno entre el 2001 y el 2007, y el otro entre el 2012 y el 2018. Este tipo de infecci\u00f3n es m\u00e1s com\u00fan en pacientes con alg\u00fan grado de compromiso del sistema inmunitario, por lo que puede presentarse en pacientes con neoplasias hematol\u00f3gicas malignas.Se presenta el caso de un hombre de 27 a\u00f1os con reca\u00edda de leucemia linfobl\u00e1stica aguda, que ingres\u00f3 con poliartralgias de cinco d\u00edas de duraci\u00f3n. Tambi\u00e9n cursaba con neutropenia febril, celulitis sin abscesos y bacteriemia por Staphylococcus aureus resistente a la meticilina para lo cual recibi\u00f3 terapia con oxacilina y cefepime. Sin embargo, persist\u00eda la neutropenia febril por lo que se sospech\u00f3 una infecci\u00f3n f\u00fangica invasora. Se tom\u00f3 un nuevo set de hemocultivos y se inici\u00f3 tratamiento antif\u00fangico.En los hemocultivos se identificaron artroconidias y mediante espectrometr\u00eda de masas por l\u00e1ser de matriz asistida de ionizaci\u00f3n-desorci\u00f3n se confirm\u00f3 la presencia de Geotrichum spp. Se ajust\u00f3 el tratamiento antif\u00fangico con deoxicolato de anfotericina B por 14 d\u00edas y voriconazol por cuatro semanas. Luego de una estancia prolongada se le dio de alta.Aunque la incidencia de la fungemia por Geotrichum spp. es baja, en pacientes con neoplasias hematol\u00f3gicas malignas debe considerarse en el contexto de una neutropenia febril que es persistente a pesar del tratamiento antimicrobiano de amplio espectro.\u00a0<\/jats:p>","DOI":"10.7705\/biomedica.6779","type":"journal-article","created":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T10:18:35Z","timestamp":1695032315000},"page":"32-40","update-policy":"https:\/\/doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":1,"title":["Geotricosis: fungemia en paciente con leucemia linfobl\u00e1stica aguda","Geotrichosis: fungemia in a patient with acute lymphoblastic leukemia"],"prefix":"10.7705","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7267-2461","authenticated-orcid":false,"given":"Jos\u00e9 Camilo","family":"\u00c1lvarez-Rodr\u00edguez","sequence":"first","affiliation":[{"name":"Grupo en Enfermedades Infecciosas en C\u00e1ncer y Alteraciones Hematol\u00f3gicas, Universidad Nacional de Colombia, Bogot\u00e1, D.C., Colombia; Grupo de Infectolog\u00eda, Instituto Nacional de Cancerolog\u00eda E.S.E, Bogot\u00e1, D.C., Colombia"},{"name":"Grupo en Enfermedades Infecciosas en C\u00e1ncer y Alteraciones Hematol\u00f3gicas, Universidad Nacional de Colombia, Bogot\u00e1, D.C., Colombia; Grupo de Infectolog\u00eda, Instituto Nacional de Cancerolog\u00eda E.S.E, Bogot\u00e1, D.C., Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4503-308X","authenticated-orcid":false,"given":"Mar\u00eda Paula","family":"Blanco-Bustos","sequence":"additional","affiliation":[{"name":"Grupo en Enfermedades Infecciosas en C\u00e1ncer y Alteraciones Hematol\u00f3gicas, Universidad Nacional de Colombia, Bogot\u00e1, D.C., Colombia; Facultad de Medicina, Universidad Nacional de Colombia, Bogot\u00e1, D.C., Colombia"},{"name":"Grupo en Enfermedades Infecciosas en C\u00e1ncer y Alteraciones Hematol\u00f3gicas, Universidad Nacional de Colombia, Bogot\u00e1, D.C., Colombia; Facultad de Medicina, Universidad Nacional de Colombia, Bogot\u00e1, D.C., Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5676-880X","authenticated-orcid":false,"given":"Sonia Isabel","family":"Cuervo-Maldonado","sequence":"additional","affiliation":[{"name":"Grupo en Enfermedades Infecciosas en C\u00e1ncer y Alteraciones Hematol\u00f3gicas, Universidad Nacional de Colombia, Bogot\u00e1, D.C., Colombia; Grupo de Infectolog\u00eda, Instituto Nacional de Cancerolog\u00eda E.S.E, Bogot\u00e1, D.C., Colombia; Facultad de Medicina, Universidad Nacional de Colombia, Bogot\u00e1, D.C., Colombia"},{"name":"Grupo en Enfermedades Infecciosas en C\u00e1ncer y Alteraciones Hematol\u00f3gicas, Universidad Nacional de Colombia, Bogot\u00e1, D.C., Colombia; Grupo de Infectolog\u00eda, Instituto Nacional de Cancerolog\u00eda E.S.E, Bogot\u00e1, D.C., Colombia; Facultad de Medicina, Universidad Nacional de Colombia, Bogot\u00e1, D.C., Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5841-1409","authenticated-orcid":false,"given":"Julio C\u00e9sar","family":"G\u00f3mez-Rinc\u00f3n","sequence":"additional","affiliation":[{"name":"Grupo en Enfermedades Infecciosas en C\u00e1ncer y Alteraciones Hematol\u00f3gicas, Universidad Nacional de Colombia, Bogot\u00e1, D.C., Colombia; Grupo de Infectolog\u00eda, Instituto Nacional de Cancerolog\u00eda E.S.E, Bogot\u00e1, D.C., Colombia;"},{"name":"Grupo en Enfermedades Infecciosas en C\u00e1ncer y Alteraciones Hematol\u00f3gicas, Universidad Nacional de Colombia, Bogot\u00e1, D.C., Colombia; Grupo de Infectolog\u00eda, Instituto Nacional de Cancerolog\u00eda E.S.E, Bogot\u00e1, D.C., Colombia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1217-7482","authenticated-orcid":false,"given":"\u00c1ngela","family":"Reyes","sequence":"additional","affiliation":[{"name":"Grupo de Microbiolog\u00eda, Laboratorio Cl\u00ednico, Instituto Nacional de Cancerolog\u00eda E.S.E, Bogot\u00e1, Colombia"},{"name":"Grupo de Microbiolog\u00eda, Laboratorio Cl\u00ednico, Instituto Nacional de Cancerolog\u00eda E.S.E, Bogot\u00e1, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4444","published-online":{"date-parts":[[2023,8,31]]},"reference":[{"key":"123392","doi-asserted-by":"crossref","unstructured":"Vargas-Esp\u00edndola LA, Cuervo-Maldonado SI, Enciso-Olivera JL, G\u00f3mez-Rinc\u00f3n JC, Jim\u00e9nez-Cetina L, S\u00e1nchez-Pedraza R, et al. 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