{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T05:19:12Z","timestamp":1791609552902,"version":"4.3.4"},"reference-count":38,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"3","license":[{"start":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T00:00:00Z","timestamp":1696032000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T00:00:00Z","timestamp":1696032000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100019867","name":"Universidad Cooperativa de \u200bColo\u200bmb\u200bia","doi-asserted-by":"publisher","award":["INV1195"],"award-info":[{"award-number":["INV1195"]}],"id":[{"id":"10.13039\/501100019867","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019867","name":"Universidad Cooperativa de \u200bColo\u200bmb\u200bia","doi-asserted-by":"publisher","award":["INV1195"],"award-info":[{"award-number":["INV1195"]}],"id":[{"id":"10.13039\/501100019867","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["Biomed."],"abstract":"<jats:p>Introducci\u00f3n. La psitacosis es una enfermedad zoon\u00f3tica causada por Chlamydia psittaci. Esta bacteria es catalogada como un agente con potencial bioterrorista y ha causado m\u00faltiples brotes en trabajadores con exposici\u00f3n laboral a aves en diferentes lugares del mundo. En Colombia, no se hace seguimiento epidemiol\u00f3gico de la infecci\u00f3n y existe una gran brecha en el conocimiento.Objetivos. Determinar la frecuencia de anticuerpos contra C. psittaci en trabajadores con exposici\u00f3n laboral a aves y sus factores asociados. Adem\u00e1s, revisar la literatura en relaci\u00f3n con los estudios sobre el tema realizados en Colombia.Materiales y m\u00e9todos. Se llev\u00f3 a cabo un estudio descriptivo, transversal, con intenci\u00f3n anal\u00edtica, en trabajadores en contacto con aves y se revis\u00f3 la literatura cient\u00edfica relacionada en Colombia. Se detectaron anticuerpos IgM e IgG contra C. psittaci en suero por microinmunofluorescencia. La descripci\u00f3n de las caracter\u00edsticas sociodemogr\u00e1ficas y de exposici\u00f3n se hizo con frecuencias y medidas de resumen. Se exploraron factores asociados por an\u00e1lisis bivariados y multivariados. La revisi\u00f3n de la literatura cient\u00edfica y gris se hizo con b\u00fasqueda estructurada.Resultados. Se analizaron 54 trabajadores en contacto con aves y se encontr\u00f3 una prevalencia de anticuerpos del 31,5 %. El ejercer funciones de sacrificio y faenado de las aves sin ser m\u00e9dico veterinario fue un factor de riesgo para la presencia de anticuerpos. Solo se encontraron cuatro estudios previos sobre C. psittaci hechos en Colombia.Conclusiones. Este estudio constituye la primera evidencia de la circulaci\u00f3n de C. psittaci en trabajadores en contacto con aves en Antioquia y el segundo reporte en el pa\u00eds. Estos hallazgos aportan desde la salud p\u00fablica a la estrategia One Health.<\/jats:p>","DOI":"10.7705\/biomedica.6832","type":"journal-article","created":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T16:31:03Z","timestamp":1697819463000},"page":"330-342","update-policy":"https:\/\/doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":5,"title":["Seropositividad de Chlamydia psittaci en trabajadores expuestos a aves y revisi\u00f3n de la literatura: evidencia de circulaci\u00f3n en Antioquia","Chlamydia psittaci seropositivity in workers exposed to birds and review of the literature: Evidence of circulation in Antioquia"],"prefix":"10.7705","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4660-9359","authenticated-orcid":false,"given":"Ana Claudia","family":"Ossa-Giraldo","sequence":"first","affiliation":[{"name":"Grupo Infettare, Facultad de Medicina, Universidad Cooperativa de Colombia, Medell\u00edn, Colombia"},{"name":"Grupo Infettare, Facultad de Medicina, Universidad Cooperativa de Colombia, Medell\u00edn, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3645-9967","authenticated-orcid":false,"given":"Xiomara","family":"\u00dasuga-Perilla","sequence":"additional","affiliation":[{"name":"Grupo Infettare, Facultad de Medicina, Universidad Cooperativa de Colombia, Medell\u00edn, Colombia"},{"name":"Grupo Infettare, Facultad de Medicina, Universidad Cooperativa de Colombia, Medell\u00edn, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4236-047X","authenticated-orcid":false,"given":"Jhon Sebasti\u00e1n","family":"Correa","sequence":"additional","affiliation":[{"name":"Grupo Infettare, Facultad de Medicina, Universidad Cooperativa de Colombia, Medell\u00edn, Colombia"},{"name":"Grupo Infettare, Facultad de Medicina, Universidad Cooperativa de Colombia, Medell\u00edn, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4231-5724","authenticated-orcid":false,"given":"Juan A.","family":"Segura","sequence":"additional","affiliation":[{"name":"Grupo Biociencias, Facultad de Ciencias de la Salud, Instituci\u00f3n Universitaria Colegio Mayor de Antioquia, Medell\u00edn, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4444","published-online":{"date-parts":[[2023,9,30]]},"reference":[{"key":"125576","unstructured":"Chu J, Yarrarapu SNS, Vaqar S, Durrani MI. Psittacosis. Treasure Island (FL): Stat Pearls Publishing; 2023. Fecha de consulta: 11 de diciembre de 2022. Disponible en: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK538305\/"},{"key":"125577","doi-asserted-by":"crossref","unstructured":"Stewardson AJ, Grayson ML. Psittacosis. Infect Dis Clin North Am. 2010;24:7-25. https:\/\/doi.org\/10.1016\/j.idc.2009.10","DOI":"10.1016\/j.idc.2009.10.003"},{"key":"125578","doi-asserted-by":"crossref","unstructured":"Kaleta EF, Taday EMA. Avian host range of Chlamydophila spp. based on isolation, antigen detection and serology. Avian Pathol. 2003;32:435-62. https:\/\/doi.org\/10.1080\/03079450310001593613","DOI":"10.1080\/03079450310001593613"},{"key":"125579","unstructured":"The Center for Food Security & Public Health, Institute for International Cooperation in Animal Biologics. Psittacosis\/Clamidosis Aviar. Fecha de consulta: 9 de diciembre de 2022. Disponible en: https:\/\/www.cfsph.iastate.edu\/Factsheets\/es\/psittacosis-es.pdf"},{"key":"125580","doi-asserted-by":"crossref","unstructured":"Rodr\u00edguez-Leo C, Camacho D, Hern\u00e1ndez V, Viettri M, Flores C, Henr\u00edquez H, et al. Primera evidencia de Chlamydia psittaci en hur\u00f3n sable (Mustella putorios furo) en Venezuela. Revista de la Facultad de Medicina Veterinaria y de Zootecnia. 2018;65. https:\/\/doi.org\/10.15446\/rfmvz.v65n2.75639","DOI":"10.15446\/rfmvz.v65n2.75639"},{"key":"125581","unstructured":"Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases. Emergency preparedness and response. Bioterrorism agents\/diseases. Fecha de consulta: 10 de diciembre de 2022. Disponible en: https:\/\/emergency.cdc.gov\/agent\/agentlist-category.asp"},{"key":"125582","doi-asserted-by":"crossref","unstructured":"Hogerwerf L, De Gier B, Baan B, van Der Hoek W. Chlamydia psittaci (psittacosis) as a cause of community-acquired pneumonia: A systematic review and meta-analysis. Epidemiol Infect. 2017;145:3096-105. https:\/\/doi.org\/10.1017\/S0950268817002060","DOI":"10.1017\/S0950268817002060"},{"key":"125583","doi-asserted-by":"crossref","unstructured":"Dickx V, van Droogenbroeck C, van Vaerenbergh B, Herman P, Braeckman L, Vanrompay D. Chlamydia psittaci, causative agent of avian chlamydiosis and human psittacosis: Risk assessment and biosafety recommendations for laboratory use. Appl Biosaf. 2012;17:82-8.","DOI":"10.1177\/153567601201700206"},{"key":"125584","unstructured":"Fenga C, Cacciola A, Di Nola C, Camileri S, Lo Giudice D, Pugliese M, et al. Serologic investigation of the prevalence of Chlamydophila psittaci in occupationally-exposed subjects in eastern Sicily. Ann Agric Environ Med. 2007;14:93-6."},{"key":"125585","doi-asserted-by":"crossref","unstructured":"Ramsey E. The psittacosis outbreak of 1929\u20131930. J Avian Med Surg. 2003;17:235-7.","DOI":"10.1647\/1082-6742(2003)017[0235:TPOO]2.0.CO;2"},{"key":"125586","doi-asserted-by":"crossref","unstructured":"Sachse K, Laroucau K, Vanrompay D. Avian chlamydiosis. Curr Clin Microbiol Rep. 2015;2:10-21. https:\/\/doi.org\/10.1007\/s40588-014-0010-y","DOI":"10.1007\/s40588-014-0010-y"},{"key":"125587","doi-asserted-by":"crossref","unstructured":"Cadario ME, Frutos MC, Arias MB, Origlia JA, Zelaya V, Madariaga MJ, et al. Epidemiological and molecular characteristics of Chlamydia psittaci from 8 human cases of psittacosis and 4 related birds in Argentina. Rev Argent Microbiol. 2017;49:323-7. https:\/\/doi.org\/10.1016\/j.ram.2017.04.001","DOI":"10.1016\/j.ram.2017.04.001"},{"key":"125588","doi-asserted-by":"crossref","unstructured":"Leo JR, Hern\u00e1ndez V, Abou Orm S, D\u00edaz Yender, Camacho D, Naillet A, et al. Chlamydia psittaci en aves psit\u00e1cidas en dos parques zool\u00f3gicos de Venezuela. Acta Biol Colomb. 2017;22. https:\/\/doi.org\/10.15446\/abc.v22n3.64742","DOI":"10.15446\/abc.v22n3.64742"},{"key":"125589","unstructured":"Vega VV. Determinaci\u00f3n de la presencia de bacterias de la familia Chlamydiaceae mediante reacci\u00f3n en cadena de la polimerasa PCR en las aves Psittaciformes de dos centros de manejo de fauna silvestre: zool\u00f3gico de Quito en Guayllabamba y Centro de Rescate Hacienda Santa Martha (tesis). Quito: Universidad San Francisco de Quito; 2010."},{"key":"125590","doi-asserted-by":"crossref","unstructured":"Pinto K, Villalobos F, Fischer C, Barrientos C, Gonz\u00e1lez-Acu\u00f1a D, Troncoso I. Detecci\u00f3n serol\u00f3gica de Chlamydophila psittaci en psit\u00e1cidos en cautiverio de la Regi\u00f3n del Biob\u00edo, Chile. Rev de Investig Vet del Per\u00fa. 2018;29:950-6. https:\/\/doi.org\/10.15381\/rivep.v29i3.14838","DOI":"10.15381\/rivep.v29i3.14838"},{"key":"125591","doi-asserted-by":"crossref","unstructured":"Raso T de F, J\u00fanior AB, Pinto AA. Evidence of Chlamydophila psittaci infection in captive Amazon parrots in Brazil. J Zoo Wildl Med. 2002;33:118- 21. https:\/\/doi.org\/10.1638\/1042-7260(2002)033[0118:EOCPII]2.0.CO;2","DOI":"10.1638\/1042-7260(2002)033[0118:EOCPII]2.0.CO;2"},{"key":"125592","doi-asserted-by":"crossref","unstructured":"Deschuyffeleer TP, Tyberghien LF, Dickx VL, Geens T, Saelen JM, Vanrompay DC, et al. Risk assessment and management of Chlamydia psittaci in poultry processing plants. Ann Occup Hyg. 2012;56:340-9. https:\/\/doi.org\/10.1093\/annhyg\/mer102","DOI":"10.1093\/annhyg\/mer102"},{"key":"125593","doi-asserted-by":"crossref","unstructured":"Rotz LD, Khan AS, Lillibridge SR, Ostroff SM, Hughes JM. Public health assessment of potential biological terrorism agents. Emerg Infect Dis. 2002;8:225-30. https:\/\/doi.org\/10.3201\/eid0802.010164","DOI":"10.3201\/eid0802.010164"},{"key":"125594","unstructured":"Centers for Disease Control and Prevention. Psittacosis. Fecha de consulta: 9 de diciembre de 2022. Disponible en: https:\/\/www.cdc.gov\/pneumonia\/atypical\/psittacosis\/about\/causes.html"},{"key":"125595","doi-asserted-by":"crossref","unstructured":"Ghai RR, Wallace RM, Kile JC, Shoemaker TR, Vieira AR, Negron ME, et al. A generalizable one health framework for the control of zoonotic diseases. Sci Rep. 2022;12:8588. https:\/\/doi.org\/10.1038\/s41598-022-12619-1","DOI":"10.1038\/s41598-022-12619-1"},{"key":"125596","doi-asserted-by":"crossref","unstructured":"Sachse K, Vretou E, Livingstone M, Borel N, Pospischil A, Longbottom D. Recent developments in the laboratory diagnosis of chlamydial infections. Vet Microbiol. 2009;135:2-21. https:\/\/doi.org\/10.1016\/j.vetmic.2008.09.040","DOI":"10.1016\/j.vetmic.2008.09.040"},{"key":"125597","doi-asserted-by":"crossref","unstructured":"Ravichandran K, Anbazhagan S, Karthik K, Angappan M, Dhayananth B. A comprehensive review on avian chlamydiosis: A neglected zoonotic disease. Trop Anim Health Prod. 2021;53:414. https:\/\/doi.org\/10.1007\/s11250-021-02859-0","DOI":"10.1007\/s11250-021-02859-0"},{"key":"125598","unstructured":"Instituto Nacional de Salud. Fichas y protocolos. Fecha de consulta: 9 de diciembre de 2022. Disponible en: https:\/\/www.ins.gov.co\/buscador-eventos\/Paginas\/Fichas-y-Protocolos.aspx"},{"key":"125599","unstructured":"Instituto Colombiano Agropecuario, Ministerio de Agricultura Rep\u00fablica de Colombia. Resoluci\u00f3n No. 3714 de 2015. Por la cual se establecen las enfermedades de declaraci\u00f3n obligatoria en Colombia. Fecha de consulta: 10 de diciembre de 2022. Disponible en: https:\/\/www.ica.gov.co\/getattachment\/3188abb6-2297-44e2-89e6-3a5dbd4db210\/2015R3714.aspx#:~:text=003714-,%22Por%20la%20cual%20se%20establecen%20las,de%20declaraci%C3%B3n%20obligatoria%20en%20Colombia%22.&text=Enfermedades%20e%20infecciones%20de%20los%20%C3%A9quidos%20Anemia%20infecciosa%20equina%20Durina,Enfermedad%20de%20Borna%20(Bunyaviridae)"},{"key":"125600","doi-asserted-by":"crossref","unstructured":"Monsalve S, Miranda J, Mattar S. Primera evidencia de circulaci\u00f3n de Chlamydophila psittaci en Colombia: posible riesgo de salud p\u00fablica. Rev Salud P\u00fablica. 2011;13:314-26. https:\/\/doi.org\/10.1590\/S0124-00642011000200013","DOI":"10.1590\/S0124-00642011000200013"},{"key":"125601","unstructured":"Vircell Microbiologists. Chlamydia: el m\u00e9todo MIF de referencia para un an\u00e1lisis espec\u00edfico de especie. Fecha de consulta: 9 de diciembre de 2022. Disponible en: https:\/\/www.vircell.com\/media\/filer_public\/fe\/e9\/fee9c3f5-1c8b-4f51-b605-78fbc706e0be\/chlamydophila_pneumoniae_ifa_es.pdf"},{"key":"125602","unstructured":"Rivera-Osorio S. Identificaci\u00f3n de Chlamydophila psittaci en aves Psit\u00e1cidas del hogar de paso de fauna silvestre \u201cLa Mar\u00eda\u201d, Pereira (tesis). Pereira: Universidad Tecnol\u00f3gica de Pereira; 2018."},{"key":"125603","unstructured":"Ocampo MC, Rend\u00f3n L, Castillo L, Ram\u00edrez A, Mosquera G, Jaramillo-Delgado I. Detecci\u00f3n serol\u00f3gica y molecular de Chlamydia psittaci en palomas (Columba livia domestica) en tres parques de la ciudad de Medell\u00edn. Rev Panam Enf Inf. 2019;2:e3. https:\/\/revistas.utp.edu.co\/index.php\/panamericana\/article\/view\/24443\/16348"},{"key":"125604","doi-asserted-by":"crossref","unstructured":"Ruiz-Laiton A, Molano-Ayala N, Garc\u00eda-Castiblanco S, Puentes-Orozco AM, Falla AC, Camargo M, et al. The prevalence of Chlamydia psittaci in confiscated Psittacidae in Colombia. Prev Vet Med. 2022;200:105591. https:\/\/doi.org\/10.1016\/j.prevetmed.2022.105591","DOI":"10.1016\/j.prevetmed.2022.105591"},{"key":"125605","doi-asserted-by":"crossref","unstructured":"Gitsels A, van Lent S, Sanders N, Vanrompay D. Chlamydia : What is on the outside does matter. Crit Rev Microbiol. 2020;46:100-19. https:\/\/doi.org\/10.1080\/1040841X.2020.1730300","DOI":"10.1080\/1040841X.2020.1730300"},{"key":"125606","doi-asserted-by":"crossref","unstructured":"Lugert R, Gro\u00df U, Masanta WO, Linsel G, Heutelbeck A, Zautner AE. Seroprevalence of Chlamydophila psittaci among employees of two German duck farms. Eur J Microbiol Immunol (Bp). 2017;7:267-73. https:\/\/doi.org\/10.1556\/1886.2017.00024","DOI":"10.1556\/1886.2017.00024"},{"key":"125607","doi-asserted-by":"crossref","unstructured":"Shaw KA, Szablewski CM, Kellner S, Kornegay L, Bair P, Brennan S, et al. Psittacosis outbreak among workers at chicken slaughter plants, Virginia and Georgia, USA, 2018. Emerg Infect Dis. 2019;25:2143-5. https:\/\/doi.org\/10.3201\/eid2511.190703","DOI":"10.3201\/eid2511.190703"},{"key":"125608","doi-asserted-by":"crossref","unstructured":"Laroucau K, Aaziz R, Meurice L, Servas V, Chossat I, Royer H, et al. Outbreak of psittacosis in a group of women exposed to Chlamydia psittaci- infected chickens. Euro Surveill. 2015;18:20:21155. https:\/\/doi.org\/10.2807\/1560-7917.es2015.20.24.21155.35","DOI":"10.2807\/1560-7917.ES2015.20.24.21155"},{"key":"125609","unstructured":"Centers for Disease Control and Prevention. Psittacosis. Information about psittacosis for employers and employees at poultry slaughter plants. Fecha de consulta: 10 de diciembre de 2022. Disponible en: https:\/\/www.cdc.gov\/pneumonia\/atypical\/psittacosis\/surveillancereporting\/outbreaks\/poultry-slaughter-plants-factsheet.html"},{"key":"125610","doi-asserted-by":"crossref","unstructured":"Balsamo G, Maxted AM, Midla JW, Murphy JM, Wohrle R, Edling TM, et al. Compendium of measures to control Chlamydia psittaci infection among humans (psittacosis) and pet birds (avian chlamydiosis), 2017. J Avian Med Surg. 2017;31:262-82. https:\/\/doi.org\/10.1647\/217-265","DOI":"10.1647\/217-265"},{"key":"125611","unstructured":"Occupational Safety and Health Administration. OSHA Fact Sheet. Personal Sheet Personal Protective Equipment. Fecha de consulta: 10 de diciembre de 2022. Disponible en: https:\/\/www.osha.gov\/sites\/default\/files\/publications\/ppe-factsheet.pdf"},{"key":"125612","doi-asserted-by":"crossref","unstructured":"Liu SY, Li KP, Hsieh MK, Chang PC, Shien JH, Ou SC. Prevalence and genotyping of Chlamydia psittaci from domestic waterfowl, companion birds, and wild birds in Taiwan. Vector Borne Zoonotic Dis. 2019;19:666-73. https:\/\/doi.org\/10.1089\/vbz.2018.2403.39","DOI":"10.1089\/vbz.2018.2403"},{"key":"125613","doi-asserted-by":"crossref","unstructured":"Vanrompay D, Harkinezhad T, van de Walle M, Beeckman D, van Droogenbroeck C, Verminnen K, et al. Chlamydophila psittaci transmission from pet birds to humans. Emerg Infect Dis. 2007;13:1108-10. https:\/\/doi.org\/10.3201\/eid1307.070074","DOI":"10.3201\/eid1307.070074"}],"container-title":["Biom\u00e9dica"],"original-title":[],"link":[{"URL":"https:\/\/revistabiomedica.org\/index.php\/biomedica\/article\/download\/6832\/5281","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistabiomedica.org\/index.php\/biomedica\/article\/download\/6832\/5386","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistabiomedica.org\/index.php\/biomedica\/article\/download\/6832\/5281","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T15:18:19Z","timestamp":1773328699000},"score":1,"resource":{"primary":{"URL":"https:\/\/revistabiomedica.org\/index.php\/biomedica\/article\/view\/6832"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,30]]},"references-count":38,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2023,9,30]]}},"URL":"https:\/\/doi.org\/10.7705\/biomedica.6832","relation":{},"ISSN":["2590-7379","0120-4157"],"issn-type":[{"value":"2590-7379","type":"electronic"},{"value":"0120-4157","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9,30]]},"assertion":[{"value":"2023-09-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}},{"value":"Yes","order":0,"name":"peer_reviewed","label":"Peer Reviewed","group":{"name":"peer_review","label":"Peer Review"}},{"value":"Instituto Nacional de Salud","name":"publisher","label":"This article is maintained by"},{"value":"Biomedica","name":"journaltitle","label":"Journal Title"},{"value":"Original articles","name":"content_type","label":"Content Type"}]}}