{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T20:51:59Z","timestamp":1773867119265,"version":"3.50.1"},"reference-count":26,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"Sp. 1","license":[{"start":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T00:00:00Z","timestamp":1693440000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T00:00:00Z","timestamp":1693440000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["Biomed."],"abstract":"<jats:p>Introduction. Fungal infections in patients with COVID-19 was one of the most debated topics during the pandemic.Objectives. To analyze the clinical characteristics and evolution of people living with HIV\/AIDS and coinfection with cryptococcus and COVID-19 (group A) or without it (group B).Materials and methods. This is an analytical and retrospective study. We reviewed medical records of patients with meningeal cryptococcosis between April 2020 and May 2021.Results. We studied 65 people living with HIV\/AIDS and with cryptococcosis infection diagnosed from April 2020 to May 2021. Fifteen patients with HIV\/AIDS suffered from cryptococcosis and COVID-19, and out of these, 14 presented meningitis (group A), while 28 suffered from meningeal cryptococcosis, but did not have COVID-19 (group B).Conclusions. No statistically significant differences were observed between the two groups (A and B) considering: intracranial hypertension, presence of Cryptococcus antigens in cerebrospinal fluid, sensorium deterioration or mortality.The detection of Cryptococcus antigens in serum by lateral flow assay was highly effective to rapidly diagnose cryptococcosis in patients with HIV\/AIDS who also developed COVID-19. Patients of both groups consulted for cryptoccocosis sometime after, in comparison with the pre-pandemic cases related to this infection.<\/jats:p>","DOI":"10.7705\/biomedica.6872","type":"journal-article","created":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T10:18:35Z","timestamp":1695032315000},"page":"206-215","update-policy":"https:\/\/doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":2,"title":["Meningeal cryptococcosis and SARS-CoV-2 infection in people living with HIV\/AIDS","Criptococosis men\u00edngea e infecci\u00f3n por SARS-CoV-2 en personas con VIH\/SIDA"],"prefix":"10.7705","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3062-7851","authenticated-orcid":false,"given":"Fernando Antonio","family":"Messina","sequence":"first","affiliation":[{"name":"Unidad Micolog\u00eda, Hospital de Enfermedades Infecciosas Francisco Javier Mu\u00f1iz, Buenos Aires, Argentina"},{"name":"Unidad Micolog\u00eda, Hospital de Enfermedades Infecciosas Francisco Javier Mu\u00f1iz, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4070-2408","authenticated-orcid":false,"given":"Andr\u00e9s","family":"Benchetrit","sequence":"additional","affiliation":[{"name":"Sala 21, Hospital de Enfermedades Infecciosas F. J. Mu\u00f1iz Hospital, Buenos Aires, Argentina"},{"name":"Sala 21, Hospital de Enfermedades Infecciosas F. J. Mu\u00f1iz Hospital, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8358-2178","authenticated-orcid":false,"given":"Andrea","family":"Bocassi","sequence":"additional","affiliation":[{"name":"Laboratorio Central Hospital de Infecciosas, Francisco Javier Mu\u00f1iz Hospital, Buenos Aires, Argentina"},{"name":"Laboratorio Central Hospital de Infecciosas, Francisco Javier Mu\u00f1iz Hospital, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3229-554X","authenticated-orcid":false,"given":"Mar\u00eda de las Mercedes","family":"Romero","sequence":"additional","affiliation":[{"name":"Unidad Micolog\u00eda, Hospital de Enfermedades Infecciosas Francisco Javier Mu\u00f1iz, Buenos Aires, Argentina"},{"name":"Unidad Micolog\u00eda, Hospital de Enfermedades Infecciosas Francisco Javier Mu\u00f1iz, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7116-1109","authenticated-orcid":false,"given":"Sof\u00eda","family":"Bauer","sequence":"additional","affiliation":[{"name":"Divisi\u00f3n SIDA, Hospital de infecciosas Francisco Javier Mu\u00f1iz Hospital, Buenos Aires, Argentina"},{"name":"Divisi\u00f3n SIDA, Hospital de infecciosas Francisco Javier Mu\u00f1iz Hospital, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1925-9835","authenticated-orcid":false,"given":"Emmanuel","family":"Mar\u00edn","sequence":"additional","affiliation":[{"name":"Unidad Micolog\u00eda, Hospital de Enfermedades Infecciosas Francisco Javier Mu\u00f1iz, Buenos Aires, Argentina"},{"name":"Unidad Micolog\u00eda, Hospital de Enfermedades Infecciosas Francisco Javier Mu\u00f1iz, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1646-4542","authenticated-orcid":false,"given":"Facundo","family":"Bertera","sequence":"additional","affiliation":[{"name":"Divisi\u00f3n Farmacia, Hospital de infecciosas Francisco Javier Mu\u00f1iz Hospital, Buenos Aires, Argentina"},{"name":"Divisi\u00f3n Farmacia, Hospital de infecciosas Francisco Javier Mu\u00f1iz Hospital, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7455-1110","authenticated-orcid":false,"given":"Guillermo","family":"Onis","sequence":"additional","affiliation":[{"name":"Sala 20, Hospital de Infecciosas Francisco Javier Mu\u00f1iz Hospital, Buenos Aires, Argentina"},{"name":"Sala 20, Hospital de Infecciosas Francisco Javier Mu\u00f1iz Hospital, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0936-6773","authenticated-orcid":false,"given":"Mat\u00edas","family":"Enzenhofer","sequence":"additional","affiliation":[{"name":"Divisi\u00f3n SIDA, Hospital de infecciosas Francisco Javier Mu\u00f1iz Hospital, Buenos Aires, Argentina"},{"name":"Divisi\u00f3n SIDA, Hospital de infecciosas Francisco Javier Mu\u00f1iz Hospital, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8846-2845","authenticated-orcid":false,"given":"Milagro","family":"S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Divisi\u00f3n SIDA, Hospital de infecciosas Francisco Javier Mu\u00f1iz Hospital, Buenos Aires, Argentina"},{"name":"Divisi\u00f3n SIDA, Hospital de infecciosas Francisco Javier Mu\u00f1iz Hospital, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5174-3443","authenticated-orcid":false,"given":"Lilia","family":"Mammana","sequence":"additional","affiliation":[{"name":"Unidad Virolog\u00eda, Hospital de Infecciosas F. J. Mu\u00f1iz Hospital, Buenos Aires, Argentina"},{"name":"Unidad Virolog\u00eda, Hospital de Infecciosas F. J. Mu\u00f1iz Hospital, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9269-7663","authenticated-orcid":false,"given":"Dana","family":"Mijalovsky","sequence":"additional","affiliation":[{"name":"Divisi\u00f3n SIDA, Hospital de infecciosas Francisco Javier Mu\u00f1iz Hospital, Buenos Aires, Argentina"},{"name":"Divisi\u00f3n SIDA, Hospital de infecciosas Francisco Javier Mu\u00f1iz Hospital, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7431-1571","authenticated-orcid":false,"given":"Gabriela","family":"Santiso","sequence":"additional","affiliation":[{"name":"Unidad Micolog\u00eda, Hospital de Enfermedades Infecciosas Francisco Javier Mu\u00f1iz, Buenos Aires, Argentina"},{"name":"Unidad Micolog\u00eda, Hospital de Enfermedades Infecciosas Francisco Javier Mu\u00f1iz, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4444","published-online":{"date-parts":[[2023,8,31]]},"reference":[{"key":"124252","doi-asserted-by":"crossref","unstructured":"Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. 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