{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T20:46:43Z","timestamp":1773866803839,"version":"3.50.1"},"reference-count":14,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"Sp. 1","license":[{"start":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T00:00:00Z","timestamp":1693440000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T00:00:00Z","timestamp":1693440000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["Biomed."],"abstract":"<jats:p>La paracoccidioidomicosis es una micosis sist\u00e9mica end\u00e9mica en Latinoam\u00e9rica. La presentaci\u00f3n m\u00e1s frecuente compromete cr\u00f3nicamente los pulmones, la piel y las mucosas. Al inicio, este paciente present\u00f3, por varios a\u00f1os, una lesi\u00f3n \u00fanica en la mucosa oral que, en ausencia de otros s\u00edntomas, se relacion\u00f3 con una neoplasia maligna, espec\u00edficamente con un carcinoma escamocelular.La diferenciaci\u00f3n entre los dos diagn\u00f3sticos se hace mediante un examen directo, un estudio histopatol\u00f3gico y cultivos iniciales y subsecuentes. Sin embargo, tales estudios no fueron concluyentes. Despu\u00e9s de varias consultas y pruebas, con los resultados del examen directo, la inmunodifusi\u00f3n y la PCR en tiempo real se confirm\u00f3 el diagn\u00f3stico de paracoccidioidomicosis cr\u00f3nica multifocal.Este caso alerta sobre la ausencia de sospecha cl\u00ednica de micosis end\u00e9micas, dada la presencia de lesiones mucocut\u00e1neas que pueden ser producidas por hongos como Paracoccidioides spp, y la importancia de considerarlas entre los diagn\u00f3sticos diferenciales.<\/jats:p>","DOI":"10.7705\/biomedica.6899","type":"journal-article","created":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T10:18:35Z","timestamp":1695032315000},"page":"69-76","update-policy":"https:\/\/doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":4,"title":["Hiperplasia pseudoepiteliomatosa: carcinoma escamocelular versus paracoccidioidomicosis oral, un caso con mirada dermatol\u00f3gica","Pseudoepitheliomatous hyperplasia: Squamous cell carcinoma versus oral paracoccidioidomycosis, a case from a dermatological perspective"],"prefix":"10.7705","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5591-7954","authenticated-orcid":false,"given":"Lina M.","family":"Osorio-Cock","sequence":"first","affiliation":[{"name":"Grupo Micolog\u00eda M\u00e9dica, Departamento de Microbiolog\u00eda y Parasitolog\u00eda, Facultad de Medicina, Universidad de Antioquia, Medell\u00edn, Colombia; Escuela de Ciencias de la Salud, Universidad Pontificia Bolivariana, Medell\u00edn, Colombia."},{"name":"Grupo Micolog\u00eda M\u00e9dica, Departamento de Microbiolog\u00eda y Parasitolog\u00eda, Facultad de Medicina, Universidad de Antioquia, Medell\u00edn, Colombia; Escuela de Ciencias de la Salud, Universidad Pontificia Bolivariana, Medell\u00edn, Colombia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0708-8247","authenticated-orcid":false,"given":"Sandra Catalina","family":"Jaramillo-Pulgar\u00edn","sequence":"additional","affiliation":[{"name":"Medic\u00e1ncer, Medell\u00edn, Colombia; Departamento de Dermatolog\u00eda, Universidad de Antioquia, Medell\u00edn, Colombia."},{"name":"Medic\u00e1ncer, Medell\u00edn, Colombia; Departamento de Dermatolog\u00eda, Universidad de Antioquia, Medell\u00edn, Colombia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-8386-1171","authenticated-orcid":false,"given":"Alba P.","family":"Ferr\u00edn-Bastidas","sequence":"additional","affiliation":[{"name":"Medic\u00e1ncer, Medell\u00edn, Colombia"},{"name":"Medic\u00e1ncer, Medell\u00edn, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-2148-0172","authenticated-orcid":false,"given":"Diana Y.","family":"Molina-Colorado","sequence":"additional","affiliation":[{"name":"Grupo Micolog\u00eda M\u00e9dica, Departamento de Microbiolog\u00eda y Parasitolog\u00eda, Facultad de Medicina, Universidad de Antioquia, Medell\u00edn, Colombia"},{"name":"Grupo Micolog\u00eda M\u00e9dica, Departamento de Microbiolog\u00eda y Parasitolog\u00eda, Facultad de Medicina, Universidad de Antioquia, Medell\u00edn, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1714-9672","authenticated-orcid":false,"given":"\u00d3scar M.","family":"G\u00f3mez-Guzm\u00e1n","sequence":"additional","affiliation":[{"name":"Grupo de Biolog\u00eda Celular y Molecular, Corporaci\u00f3n para Investigaciones Biol\u00f3gicas, Medell\u00edn, Colombia"},{"name":"Grupo de Biolog\u00eda Celular y Molecular, Corporaci\u00f3n para Investigaciones Biol\u00f3gicas, Medell\u00edn, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6199-8570","authenticated-orcid":false,"given":"Alejandra","family":"Zuluaga","sequence":"additional","affiliation":[{"name":"Grupo de Micolog\u00eda M\u00e9dica y Experimental, Corporaci\u00f3n para Investigaciones Biol\u00f3gicas, Medell\u00edn, Colombia"},{"name":"Grupo de Micolog\u00eda M\u00e9dica y Experimental, Corporaci\u00f3n para Investigaciones Biol\u00f3gicas, Medell\u00edn, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8594-9087","authenticated-orcid":false,"given":"Juan G.","family":"McEwen-Ochoa","sequence":"additional","affiliation":[{"name":"Grupo Micolog\u00eda M\u00e9dica, Departamento de Microbiolog\u00eda y Parasitolog\u00eda, Facultad de Medicina, Universidad de Antioquia, Medell\u00edn, Colombia; Grupo de Biolog\u00eda Celular y Molecular, Corporaci\u00f3n para Investigaciones Biol\u00f3gicas, Medell\u00edn, Colombia"},{"name":"Grupo Micolog\u00eda M\u00e9dica, Departamento de Microbiolog\u00eda y Parasitolog\u00eda, Facultad de Medicina, Universidad de Antioquia, Medell\u00edn, Colombia; Grupo de Biolog\u00eda Celular y Molecular, Corporaci\u00f3n para Investigaciones Biol\u00f3gicas, Medell\u00edn, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6834-027X","authenticated-orcid":false,"given":"Martha E.","family":"Ur\u00e1n-Jim\u00e9nez","sequence":"additional","affiliation":[{"name":"Grupo Micolog\u00eda M\u00e9dica, Departamento de Microbiolog\u00eda y Parasitolog\u00eda, Facultad de Medicina, Universidad de Antioquia, Medell\u00edn, Colombia"},{"name":"Grupo Micolog\u00eda M\u00e9dica, Departamento de Microbiolog\u00eda y Parasitolog\u00eda, Facultad de Medicina, Universidad de Antioquia, Medell\u00edn, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7493-4258","authenticated-orcid":false,"given":"Mar\u00eda del Pilar","family":"Jim\u00e9nez-Alzate","sequence":"additional","affiliation":[{"name":"Grupo Micolog\u00eda M\u00e9dica, Departamento de Microbiolog\u00eda y Parasitolog\u00eda, Facultad de Medicina, Universidad de Antioquia, Medell\u00edn, Colombia"},{"name":"Grupo Micolog\u00eda M\u00e9dica, Departamento de Microbiolog\u00eda y Parasitolog\u00eda, Facultad de Medicina, Universidad de Antioquia, Medell\u00edn, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4444","published-online":{"date-parts":[[2023,8,31]]},"reference":[{"key":"123597","doi-asserted-by":"crossref","unstructured":"Hahn RC, Hagen F, Poncio Mendes R, Burger E, Ferreira Nery A, Pereira Siqueira N, et al. 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