{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T04:17:27Z","timestamp":1773375447269,"version":"3.50.1"},"reference-count":26,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"Sp. 3","license":[{"start":{"date-parts":[[2023,12,29]],"date-time":"2023-12-29T00:00:00Z","timestamp":1703808000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,12,29]],"date-time":"2023-12-29T00:00:00Z","timestamp":1703808000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100019346","name":"Instituto Nacional de Cancerolog\u00eda","doi-asserted-by":"publisher","award":["41030311-7"],"award-info":[{"award-number":["41030311-7"]}],"id":[{"id":"10.13039\/100019346","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019346","name":"Instituto Nacional de Cancerolog\u00eda","doi-asserted-by":"publisher","award":["41030311-7"],"award-info":[{"award-number":["41030311-7"]}],"id":[{"id":"10.13039\/100019346","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["Biomed."],"abstract":"<jats:p>Introducci\u00f3n. El c\u00e1ncer de cuello uterino es un problema de salud p\u00fablica relevante en pa\u00edses de ingresos medios y bajos. El seguimiento de mujeres con tamizaci\u00f3n positiva y el acceso a tratamiento para neoplasia intraepitelial cervical (NIC) son retos mayores en estos pa\u00edses.Objetivo. Evaluar la efectividad de la crioterapia suministrada por enfermeras en casos de neoplasia intraepitelial de c\u00e9rvix.Materiales y m\u00e9todos. Se hizo la inspecci\u00f3n visual directa con \u00e1cido ac\u00e9tico y soluci\u00f3n yodada (VIA-VILI), y se practic\u00f3 colposcopia con biopsia, a mujeres entre los 25 y los 59 a\u00f1os, residentes en zonas de bajos ingresos de Bogot\u00e1. Profesionales de enfermer\u00eda entrenados ofrecieron tratamiento inmediato con crioterapia a mujeres positivas en la inspecci\u00f3n visual. Se les practic\u00f3 colposcopia con biopsia antes del tratamiento y en un control a los 12 meses. Se evalu\u00f3 la efectividad mediante tasas de curaci\u00f3n (resultado: sin lesi\u00f3n) y regresi\u00f3n de NIC2\/3 (resultado: \u2264NIC1), por verificaci\u00f3n colposc\u00f3pica e histol\u00f3gica.Resultados. Se tamizaron 4.957 mujeres. En total, 499 fueron positivas y 472 aceptaron el tratamiento inmediato. Recibieron crioterapia por enfermer\u00eda 365 mujeres (11 NIC2\/3). La tasa de curaci\u00f3n fue del 72 % (IC95%: 39-94 %) por verificaci\u00f3n colposc\u00f3pica, y del 40 % (IC95%: 22-85 %) por histolog\u00eda. Las tasas de regresi\u00f3n fueron del 100 y el 60 %, respectivamente. Se reportaron dos eventos adversos no graves relacionados.Conclusiones. Las tasas de curaci\u00f3n y regresi\u00f3n por verificaci\u00f3n colposc\u00f3pica son similares a las reportadas con crioterapia administrada por m\u00e9dicos. El tama\u00f1o de la muestra con NIC2\/3 dificulta la comparaci\u00f3n por tipo de verificaci\u00f3n. Los hallazgos apoyan la implementaci\u00f3n de estrategias de \u201cver y tratar\u201d por parte de enfermer\u00eda en poblaciones con acceso limitado a servicios de salud.<\/jats:p>","DOI":"10.7705\/biomedica.6966","type":"journal-article","created":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T09:35:40Z","timestamp":1704792940000},"page":"79-87","update-policy":"https:\/\/doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":1,"title":["Efectividad de la crioterapia suministrada por enfermeras para lesiones preneopl\u00e1sicas del cuello uterino","Effectiveness of cryotherapy delivered by nurses for treatment of cervical preneoplasic lesions"],"prefix":"10.7705","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8207-0018","authenticated-orcid":false,"given":"Edwin","family":"Pulido","sequence":"first","affiliation":[{"name":"Centro Javeriano de Oncolog\u00eda, Hospital Universitario San Ignacio, Bogot\u00e1, D.C., Colombia"},{"name":"Centro Javeriano de Oncolog\u00eda, Hospital Universitario San Ignacio, Bogot\u00e1, D.C., Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6439-0269","authenticated-orcid":false,"given":"Mauricio","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Emeritus, Instituto Nacional de Cancerolog\u00eda, Bogot\u00e1, D.C., Colombia"},{"name":"Emeritus, Instituto Nacional de Cancerolog\u00eda, Bogot\u00e1, D.C., Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9329-6810","authenticated-orcid":false,"given":"\u00d3scar","family":"Gamboa","sequence":"additional","affiliation":[{"name":"Centro Javeriano de Oncolog\u00eda, Hospital Universitario San Ignacio, Bogot\u00e1, D.C., Colombia;\u00a0Servicio de Radioterapia, Instituto Nacional de Cancerolog\u00eda, Bogot\u00e1, D.C., Colombia"},{"name":"Centro Javeriano de Oncolog\u00eda, Hospital Universitario San Ignacio, Bogot\u00e1, D.C., Colombia;\u00a0Servicio de Radioterapia, Instituto Nacional de Cancerolog\u00eda, Bogot\u00e1, D.C., Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7030-477X","authenticated-orcid":false,"given":"Jairo","family":"Bonilla","sequence":"additional","affiliation":[{"name":"Colpolatina SAS, Bogot\u00e1, D.C., Colombia"},{"name":"Colpolatina SAS, Bogot\u00e1, D.C., Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9082-2555","authenticated-orcid":false,"given":"Joaqu\u00edn","family":"Luna","sequence":"additional","affiliation":[{"name":"Colsanitas EPS, Bogot\u00e1, D.C., Colombia"},{"name":"Colsanitas EPS, Bogot\u00e1, D.C., Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7187-9946","authenticated-orcid":false,"given":"Ra\u00fal","family":"Murillo","sequence":"additional","affiliation":[{"name":"Centro Javeriano de Oncolog\u00eda, Hospital Universitario San Ignacio, Bogot\u00e1, D.C., Colombia; Facultad de Medicina, Pontificia Universidad Javeriana, Bogot\u00e1, D.C., Colombia"},{"name":"Centro Javeriano de Oncolog\u00eda, Hospital Universitario San Ignacio, Bogot\u00e1, D.C., Colombia; Facultad de Medicina, Pontificia Universidad Javeriana, Bogot\u00e1, D.C., Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4444","published-online":{"date-parts":[[2023,12,29]]},"reference":[{"key":"128971","doi-asserted-by":"crossref","unstructured":"Hern\u00e1ndez-Vargas JA, Ram\u00edrez-Barbosa PX, Valbuena-Garc\u00eda AM, Acu\u00f1a L, Gonz\u00e1lez-Diaz JA. 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