{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T01:42:16Z","timestamp":1773366136433,"version":"3.50.1"},"reference-count":26,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"2","license":[{"start":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T00:00:00Z","timestamp":1717027200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T00:00:00Z","timestamp":1717027200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["Biomed."],"abstract":"<jats:p>Introduction. Medications are a fundamental part of the treatment of multiple pathologies. However, despite their benefits, some are considered potentially inappropriate medications for older people given their safety profile. Epidemiological data differences related to potentially inappropriate medications make it difficult to determine their effects on elderly people.Objective. To estimate the prevalence and types of potentially inappropriate medications using the 2019 Beers Criteria\u00ae in a cohort of adults older than 65 years.Materials and methods. We performed an observational, multicenter, retrospective, longitudinal study of a four-year follow-up of potentially inappropriate medications in community-dwelling older adults.Results. We followed 820 participants from five cities for four years (2012-2016) and evaluated them in three different moments (m1 = 2012, m2 = 2014, and m3 = 2016). The average age was 69.07 years, and 50.9% were women. The potentially inappropriate medication prevalence in the participants was 40.24%. The potentially inappropriate medications\u2019 mean among the studied subjects in the first moment was 1.65 (SD = 0.963), in the second was 1.73 (SD = 1.032), and in the third was 1.62 (SD = 0.915). There were no statistical differences between measurements (Friedman test, value = 0.204). The most frequent potentially inappropriate medications categories were gastrointestinal (39.4%), analgesics (18.8%), delirium-related drugs (15.4%), benzodiazepines (15.2%), and cardiovascular (14.2%).Conclusions. About half of the population of the community-dwelling older adults had prescriptions of potentially inappropriate medications in a sustained manner and without significant variability over time. Mainly potentially inappropriate medications were gastrointestinal and cardiovascular drugs, analgesics, delirium-related drugs, and benzodiazepines.<\/jats:p>","DOI":"10.7705\/biomedica.6992","type":"journal-article","created":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T11:00:55Z","timestamp":1722423655000},"page":"207-216","update-policy":"https:\/\/doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":4,"title":["Potentially inappropriate medication on communitydwelling older adults: Longitudinal analysis using the International Mobility in Aging Study","Medicaci\u00f3n potencialmente inapropiada en adultos mayores de la comunidad: an\u00e1lisis longitudinal del estudio IMIAS"],"prefix":"10.7705","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7442-2247","authenticated-orcid":false,"given":"Edison","family":"Pineda","sequence":"first","affiliation":[{"name":"Facultad de Ciencias para la Salud, Universidad de Caldas, Manizales, Colombia;\u00a0Grupo de Investigaci\u00f3n en Gerontolog\u00eda y Geriatr\u00eda, Facultad de Ciencias para la Salud, Universidad de Caldas, Manizales, Colombia"},{"name":"Facultad de Ciencias para la Salud, Universidad de Caldas, Manizales, Colombia;\u00a0Grupo de Investigaci\u00f3n en Gerontolog\u00eda y Geriatr\u00eda, Facultad de Ciencias para la Salud, Universidad de Caldas, Manizales, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6014-2292","authenticated-orcid":false,"given":"Alejandra","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Hospital Alma Mater de Antioquia, Medell\u00edn, Colombia"},{"name":"Hospital Alma Mater de Antioquia, Medell\u00edn, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8063-2301","authenticated-orcid":false,"given":"Carmen Luc\u00eda","family":"Curcio","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias para la Salud, Universidad de Caldas, Manizales, Colombia;\u00a0Grupo de Investigaci\u00f3n en Gerontolog\u00eda y Geriatr\u00eda, Facultad de Ciencias para la Salud, Universidad de Caldas, Manizales, Colombia"},{"name":"Facultad de Ciencias para la Salud, Universidad de Caldas, Manizales, Colombia;\u00a0Grupo de Investigaci\u00f3n en Gerontolog\u00eda y Geriatr\u00eda, Facultad de Ciencias para la Salud, Universidad de Caldas, Manizales, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7509-8853","authenticated-orcid":false,"given":"Juliana","family":"Fernandes de Souza","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Fisioterapia e Sa\u00fade Coletiva, Departamento de Fisioterapia da Universidade Federal de Pernambuco, Recife, Brasil"},{"name":"Laborat\u00f3rio de Fisioterapia e Sa\u00fade Coletiva, Departamento de Fisioterapia da Universidade Federal de Pernambuco, Recife, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3605-409X","authenticated-orcid":false,"given":"Afshin","family":"Vafaei","sequence":"additional","affiliation":[{"name":"School of Health Studies, Western University, Kingston, ON, Canada"},{"name":"School of Health Studies, Western University, Kingston, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4360-8174","authenticated-orcid":false,"given":"Jos\u00e9 Fernando","family":"G\u00f3mez","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias para la Salud, Universidad de Caldas, Manizales, Colombia;\u00a0Grupo de Investigaci\u00f3n en Gerontolog\u00eda y Geriatr\u00eda, Facultad de Ciencias para la Salud, Universidad de Caldas, Manizales, Colombia"},{"name":"Facultad de Ciencias para la Salud, Universidad de Caldas, Manizales, Colombia;\u00a0Grupo de Investigaci\u00f3n en Gerontolog\u00eda y Geriatr\u00eda, Facultad de Ciencias para la Salud, Universidad de Caldas, Manizales, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4444","published-online":{"date-parts":[[2024,5,30]]},"reference":[{"key":"133953","doi-asserted-by":"crossref","unstructured":"Charles L, Kumar E, Elghol E, Dobbs B, Tian PGJ, Babenko O. 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Prevalence and impact of potentially inappropriate medication on community-dwelling older adults. Biom\u00e9dica. 2021;41:111-22. https:\/\/doi.org\/10.7705\/biomedica.5787","DOI":"10.7705\/biomedica.5787"},{"key":"133957","doi-asserted-by":"crossref","unstructured":"Sim\u00f5es PA, Santiago LM, Maur\u00edcio K, Sim\u00f5es JA. Prevalence of potentially inappropriate medication in the older adult population within primary care in Portugal: A nationwide crosssectional study. Patient Prefer Adherence. 2019;13:1569-76. https:\/\/doi.org\/10.2147\/PPA.S219346","DOI":"10.2147\/PPA.S219346"},{"key":"133958","doi-asserted-by":"crossref","unstructured":"Manias E, Soh CH, Kabir MdZ, Reijnierse EM, Maier AB. Associations between inappropriate medication use and (instrumental) activities of daily living in geriatric rehabilitation inpatients: RESORT study. 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