{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T22:18:12Z","timestamp":1780525092755,"version":"3.54.1"},"reference-count":17,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"3","license":[{"start":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T00:00:00Z","timestamp":1754870400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T00:00:00Z","timestamp":1754870400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["Biomed."],"abstract":"<jats:p>El pez le\u00f3n (Pterois volitans) es una especie invasora del mar Caribe que puede inyectar veneno por medio de sus espinas. Se informa un caso de este tipo de accidente, que podr\u00eda convertirse en un riesgo emergente para la salud p\u00fablica en Colombia. Se trata de una mujer sana de 59 a\u00f1os que sufri\u00f3 una lesi\u00f3n por pinchazo con la aleta de un pez le\u00f3n en el cuarto dedo de la mano izquierda mientras buceaba en Aruba.La paciente fue tratada en el lugar del accidente con compresas calientes, antihistam\u00ednicos y corticoides sist\u00e9micos; no obstante, experiment\u00f3 dolor intenso, frialdad y palidez en todo el dedo afectado.Al d\u00eda siguiente, la paciente viaj\u00f3 a Bogot\u00e1 (Colombia) y, posteriormente, present\u00f3 edema, p\u00e9rdida de la sensibilidad y cambios en la coloraci\u00f3n de la piel. En el servicio de urgencias donde consult\u00f3, se administr\u00f3 un tratamiento farmacol\u00f3gico con antiagregante plaquetario (100 mg de \u00e1cido acetilsalic\u00edlico por v\u00eda oral), anticoagulante (60 mg de enoxaparina por v\u00eda subcut\u00e1nea) y un antagonista del calcio para controlar el vasoespasmo (30 mg de nifedipino por v\u00eda oral); adem\u00e1s, se solicitaron estudios paracl\u00ednicos complementarios. Estos ex\u00e1menes y la ecograf\u00eda Doppler de los vasos arteriales del miembro superior izquierdo, fueron normales. El tratamiento fue exitoso y la paciente se recuper\u00f3 por completo.Dada la novedad del caso en Colombia y su evoluci\u00f3n favorable, a pesar de las limitaciones del tratamiento inicial y de lo tard\u00edo del farmacol\u00f3gico, se presenta una discusi\u00f3n amplia basada en la revisi\u00f3n de la literatura disponible.<\/jats:p>","DOI":"10.7705\/biomedica.7230","type":"journal-article","created":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T18:50:07Z","timestamp":1755283807000},"page":"337-344","update-policy":"https:\/\/doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":1,"title":["Caso de envenenamiento por picadura de pez le\u00f3n, atendido en un servicio de urgencias de Colombia","Lionfish envenomation case treated in an emergency unit in Colombia"],"prefix":"10.7705","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3756-0074","authenticated-orcid":false,"given":"Mar\u00eda Alejandra","family":"Montoya-Giraldo","sequence":"first","affiliation":[{"name":"Laboratorio Integrado de Medicina Especializada, Hospital Alma Mater de Antioquia, Facultad de Medicina, Universidad de Antioquia, Medell\u00edn, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8593-0036","authenticated-orcid":false,"given":"Sebasti\u00e1n","family":"Franco-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Oficina de Coordinaci\u00f3n, Unidad Funcional de Urgencias, Los Cobos Medical Center, Bogot\u00e1, D.C., Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5656-4153","authenticated-orcid":false,"given":"Andr\u00e9s F.","family":"Zuluaga","sequence":"additional","affiliation":[{"name":"Laboratorio Integrado de Medicina Especializada, Hospital Alma Mater de Antioquia, Facultad de Medicina, Universidad de Antioquia, Medell\u00edn, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4444","published-online":{"date-parts":[[2025,8,11]]},"reference":[{"key":"150309","doi-asserted-by":"crossref","unstructured":"1. Norton BB, Norton SA. Lionfish envenomation in Caribbean and Atlantic waters: Climate change and invasive species. Int J Womens Dermatol. 2021;7:120-3. https:\/\/doi.org\/10.1016\/j.ijwd.2020.05.016","DOI":"10.1016\/j.ijwd.2020.05.016"},{"key":"150310","unstructured":"2. Escobar Rom\u00e1n R, Leiva Acebey L, Sor\u00ed Le\u00f3n Y. Pez le\u00f3n (Pterois volitans) y su impacto en la salud humana. Gac Med Espirit. 2015;17:82-92."},{"key":"150311","unstructured":"3. Marineros L. Incidencia y primeros accidentes del pez le\u00f3n (Pterois volitans) en aguas continentales del Caribe de Honduras. Bioma. 2014;15:29-35."},{"key":"150312","doi-asserted-by":"crossref","unstructured":"4. Vetrano SJ, Lebowitz JB, Marcus S. Lionfish envenomation. J Emerg Med. 2002;23:379-82. https:\/\/doi.org\/10.1016\/s0736-4679(02)00572-3","DOI":"10.1016\/S0736-4679(02)00572-3"},{"key":"150313","doi-asserted-by":"crossref","unstructured":"5. Garyfallou GT, Madden JF. Lionfish envenomation. Ann Emerg Med. 1996;28:456-7. https:\/\/doi.org\/10.1016\/s0196-0644(96)70018-5","DOI":"10.1016\/S0196-0644(96)70018-5"},{"key":"150314","doi-asserted-by":"crossref","unstructured":"6. Pastore D, Pacifici F, Ciao G, Bedin V, Pasquantonio G, Della-Morte D. Far infrared technology (FIT) therapy patches protect from inflammation, oxidative stress, and promote cellular vitality. Curr Pharm Des. 2020;26:4323-9. https:\/\/doi.org\/10.2174\/1381612826666200427112023","DOI":"10.2174\/1381612826666200427112023"},{"key":"150315","doi-asserted-by":"crossref","unstructured":"7. Hardison DR, Holland WC, Darius HT, Chinain M, Tester PA, Shea D, et al. Investigation of ciguatoxins in invasive lionfish from the greater Caribbean region: Implications for fishery development. PLoS ONE. 2018;13:e0198358. https:\/\/doi.org\/10.1371\/journal.pone.0198358","DOI":"10.1371\/journal.pone.0198358"},{"key":"150316","doi-asserted-by":"crossref","unstructured":"8. Schult RF, Acquisto NM, Stair CK, Wiegand TJ. A case of lionfish envenomation presenting to an inland emergency department. Case Rep Emerg Med. 2017;2017:5893563. https:\/\/doi.org\/10.1155\/2017\/5893563","DOI":"10.1155\/2017\/5893563"},{"key":"150317","unstructured":"9. P\u00e9rez Bravo \u00c1. An\u00e1lisis preliminar de los componentes proteicos del veneno del pez le\u00f3n Pterois volitans de la costa de Santa Marta y evaluaci\u00f3n de su actividad biol\u00f3gica. Bogot\u00e1: Universidad Nacional de Colombia; 2018."},{"key":"150318","unstructured":"10. Rensch G, Murphy-Lavoie HM. Lionfish, scorpionfish, and stonefish toxicity. Treasure Island (FL): StatPearls Publishing; 2023."},{"key":"150319","doi-asserted-by":"crossref","unstructured":"11. Haddad V, Stolf HO, Risk JY, Fran\u00e7a FOS, Cardoso JLC. Report of 15 injuries caused by lionfish (Pterois volitans) in aquarists in Brazil: A critical assessment of the severity of envenomations. J Venom Anim Toxins Incl Trop Dis. 2015:21:8. https:\/\/doi.org\/10.1186\/s40409-015-0007-x","DOI":"10.1186\/s40409-015-0007-x"},{"key":"150320","doi-asserted-by":"crossref","unstructured":"12. Resiere D, Cerland L, De Haro L, Valentino R, Criquet-Hayot A, Chabartier C, et al. Envenomation by the invasive Pterois volitans species (lionfish) in the French West Indies--A two-year prospective study in Martinique. Clin Toxicol (Phila). 2016;54:313-8. https:\/\/doi.org\/10.3109\/15563650.2016.1143100","DOI":"10.3109\/15563650.2016.1143100"},{"key":"150321","doi-asserted-by":"crossref","unstructured":"13. Mouchbahani-Constance S, Lesperance LS, Petitjean H, Davidova A, Macpherson A, Prescott SA, et al. Lionfish venom elicits pain predominantly through the activation of non-peptidergic nociceptors. Pain. 2018;159:2255-66. https:\/\/doi.org\/10.1097\/j.pain.0000000000001326","DOI":"10.1097\/j.pain.0000000000001326"},{"key":"150322","doi-asserted-by":"crossref","unstructured":"14. Latremoliere A, Woolf CJ. Central sensitization: A generator of pain hypersensitivity by central neural plasticity. J Pain. 2009;10:895-926. https:\/\/doi.org\/10.1016\/j.jpain.2009.06.012","DOI":"10.1016\/j.jpain.2009.06.012"},{"key":"150323","doi-asserted-by":"crossref","unstructured":"15. Montoya-Giraldo MA, D\u00edaz LF, G\u00f3mez UE, Quintero J, Zuluaga AF. Use of low-molecular weight heparin in severe paraquat poisoning: A case report. J Med Case Rep. 2020;14:240. https:\/\/doi.org\/10.1186\/s13256-020-02565-9","DOI":"10.1186\/s13256-020-02565-9"},{"key":"150324","unstructured":"16. Hobday D, Chadha P, Din AH, Geh J. Denaturing the lionfish. Eplasty. 2016;16:ic20."},{"key":"150325","unstructured":"17. Aktas S, Mirasoglu B. Lionfish envenomation: Clinical aspect and management. J Black Sea Mediterr Environ. 2017;23:81."}],"container-title":["Biom\u00e9dica"],"original-title":[],"link":[{"URL":"https:\/\/revistabiomedica.org\/index.php\/biomedica\/article\/download\/7230\/5711","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistabiomedica.org\/index.php\/biomedica\/article\/download\/7230\/5853","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistabiomedica.org\/index.php\/biomedica\/article\/download\/7230\/5711","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T21:46:07Z","timestamp":1773265567000},"score":1,"resource":{"primary":{"URL":"https:\/\/revistabiomedica.org\/index.php\/biomedica\/article\/view\/7230"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,11]]},"references-count":17,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,8,11]]}},"URL":"https:\/\/doi.org\/10.7705\/biomedica.7230","relation":{},"ISSN":["2590-7379","0120-4157"],"issn-type":[{"value":"2590-7379","type":"electronic"},{"value":"0120-4157","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8,11]]},"assertion":[{"value":"2025-08-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}},{"value":"Yes","order":0,"name":"peer_reviewed","label":"Peer Reviewed","group":{"name":"peer_review","label":"Peer Review"}},{"value":"Instituto Nacional de Salud","name":"publisher","label":"This article is maintained by"},{"value":"Biomedica","name":"journaltitle","label":"Journal Title"},{"value":"Presentaci\u00f3n de caso","name":"content_type","label":"Content Type"}]}}