{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T09:41:46Z","timestamp":1792489306908,"version":"4.5.0"},"reference-count":31,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"2","license":[{"start":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T00:00:00Z","timestamp":1717027200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T00:00:00Z","timestamp":1717027200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["Biomed."],"abstract":"<jats:p>Introducci\u00f3n. Colombia alberga dos millones de ind\u00edgenas, que viven en condiciones de pobreza y tienen deficiencias en salud, por lo cual est\u00e1n expuestos a contraer infecciones virales como la hepatitis B. El departamento del Amazonas presenta una gran prevalencia del virus y barreras para acceder a la vacunaci\u00f3n; por esto, parte de la poblaci\u00f3n es propensa a la infecci\u00f3n.Objetivo. Identificar factores asociados con la infecci\u00f3n por el virus de la hepatitis B en ind\u00edgenas colombianos.Materiales y m\u00e9todos. Se llev\u00f3 a cabo un estudio de casos y controles en mayores de 18 a\u00f1os de cuatro departamentos del pa\u00eds. Los casos se identificaron mediante el registro nacional de notificaci\u00f3n de hepatitis B (2015-2022). Los controles seleccionados de manera concurrente fueron pareados con los casos por edad, sexo, etnia y departamento. En una encuesta se consignaron las caracter\u00edsticas sociodemogr\u00e1ficas, los factores asociados con el contacto con sangre y fluidos, las pr\u00e1cticas socioculturales y los antecedentes de vacunaci\u00f3n. El proyecto fue aprobado por Comit\u00e9 de \u00c9tica de la Universidad de Antioquia.Resultados. Participaron 75 casos y 150 controles de 13 grupos \u00e9tnicos. El departamento del Amazonas aport\u00f3 el 49 % de los participantes (83 % mujeres) con una mediana de edad de 30 a\u00f1os (RIC = 27-37). Los factores asociados con una mayor probabilidad de contraer la infecci\u00f3n fueron el antecedente de alg\u00fan familiar infectado con el virus de la hepatitis B (OR ajustado = 2,61) (IC95%: 1,09-6,27) y n\u00famero de embarazos en mujeres, (OR ajustado = 1,61) (IC95%: 1,02-2,54). La vacunaci\u00f3n mostr\u00f3 un efecto protector sin asociaci\u00f3n significativa.Conclusi\u00f3n. Los aspectos asociados con la convivencia familiar y el n\u00famero de embarazos contribuyen a una potencial transmisi\u00f3n vertical y horizontal del virus. No se identificaron pr\u00e1cticas culturales asociadas. Se requieren estrategias novedosas y diferenciales para reducir la transmisi\u00f3n del virus de la hepatitis B en poblaciones ind\u00edgenas.<\/jats:p>","DOI":"10.7705\/biomedica.7243","type":"journal-article","created":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T11:00:55Z","timestamp":1722423655000},"page":"144-154","update-policy":"https:\/\/doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":1,"title":["Factores asociados con la infecci\u00f3n por el virus de la hepatitis B en comunidades ind\u00edgenas de Colombia","Factors associated with hepatitis B virus infection in indigenous communities of Colombia"],"prefix":"10.7705","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9996-4445","authenticated-orcid":false,"given":"Jaime","family":"Mart\u00ednez-Gallego","sequence":"first","affiliation":[{"name":"Grupo de Epidemiolog\u00eda, Facultad Nacional de Salud P\u00fablica, Universidad de Antioquia, Medell\u00edn, Colombia"},{"name":"Grupo de Epidemiolog\u00eda, Facultad Nacional de Salud P\u00fablica, Universidad de Antioquia, Medell\u00edn, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7322-5970","authenticated-orcid":false,"given":"Diana","family":"Castro-Arroyave","sequence":"additional","affiliation":[{"name":"Grupo de Estudio en Pedagog\u00eda, Infancia y Desarrollo Humano - GEPIDH, Facultad de Educaci\u00f3n, Universidad de Antioquia, Medell\u00edn, Colombia"},{"name":"Grupo de Estudio en Pedagog\u00eda, Infancia y Desarrollo Humano - GEPIDH, Facultad de Educaci\u00f3n, Universidad de Antioquia, Medell\u00edn, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7356-7751","authenticated-orcid":false,"given":"Juan Carlos","family":"Quintero","sequence":"additional","affiliation":[{"name":"Grupo de Epidemiolog\u00eda, Facultad Nacional de Salud P\u00fablica, Universidad de Antioquia, Medell\u00edn, Colombia"},{"name":"Grupo de Epidemiolog\u00eda, Facultad Nacional de Salud P\u00fablica, Universidad de Antioquia, Medell\u00edn, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9436-7935","authenticated-orcid":false,"given":"Fernando","family":"De la Hoz","sequence":"additional","affiliation":[{"name":"Facultad de Medicina, Universidad Nacional de Colombia, Bogot\u00e1, D. C., Colombia"},{"name":"Facultad de Medicina, Universidad Nacional de Colombia, Bogot\u00e1, D. C., Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7536-2194","authenticated-orcid":false,"given":"Melissa","family":"Montoya","sequence":"additional","affiliation":[{"name":"Facultad de Medicina, Universidad Nacional de Colombia, Bogot\u00e1, D. C., Colombia"},{"name":"Facultad de Medicina, Universidad Nacional de Colombia, Bogot\u00e1, D. C., Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8299-9975","authenticated-orcid":false,"given":"Isabela","family":"Palacio","sequence":"additional","affiliation":[{"name":"Grupo de Gastrohepatolog\u00eda, Facultad de Medicina, Universidad de Antioquia, Medell\u00edn, Colombia"},{"name":"Grupo de Gastrohepatolog\u00eda, Facultad de Medicina, Universidad de Antioquia, Medell\u00edn, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2610-9306","authenticated-orcid":false,"given":"Mar\u00eda Cristina","family":"Navas","sequence":"additional","affiliation":[{"name":"Grupo de Estudio en Pedagog\u00eda, Infancia y Desarrollo Humano - GEPIDH, Facultad de Educaci\u00f3n, Universidad de Antioquia, Medell\u00edn, Colombia"},{"name":"Grupo de Estudio en Pedagog\u00eda, Infancia y Desarrollo Humano - GEPIDH, Facultad de Educaci\u00f3n, Universidad de Antioquia, Medell\u00edn, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1906-6048","authenticated-orcid":false,"given":"Carlos","family":"Rojas","sequence":"additional","affiliation":[{"name":"Grupo de Epidemiolog\u00eda, Facultad Nacional de Salud P\u00fablica, Universidad de Antioquia, Medell\u00edn, Colombia"},{"name":"Grupo de Epidemiolog\u00eda, Facultad Nacional de Salud P\u00fablica, Universidad de Antioquia, Medell\u00edn, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4444","published-online":{"date-parts":[[2024,5,30]]},"reference":[{"key":"133702","unstructured":"Organizaci\u00f3n Panamericana de la Salud. 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