{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T01:42:27Z","timestamp":1773366147334,"version":"3.50.1"},"reference-count":32,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"Sp. 2","license":[{"start":{"date-parts":[[2024,12,23]],"date-time":"2024-12-23T00:00:00Z","timestamp":1734912000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,12,23]],"date-time":"2024-12-23T00:00:00Z","timestamp":1734912000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["Biomed."],"abstract":"<jats:p>Introducci\u00f3n. La deficiencia predominantemente de anticuerpos es el grupo de errores inmun\u00f3logicos innatos m\u00e1s frecuente, sin embargo, hay poca informaci\u00f3n sobre el estado nutricional de los pacientes afectados.Objetivo. Caracterizar el estado nutricional de pacientes colombianos con deficiencias predominantemente de anticuerpos.Materiales y m\u00e9todos. Se analizaron las historias cl\u00ednicas de los pacientes con deficiencias predominantemente de anticuerpos en un hospital pedi\u00e1trico de Bogot\u00e1.Resultados. Se analizaron 55 historias cl\u00ednicas. Los diagn\u00f3sticos m\u00e1s frecuentes fueron la deficiencia espec\u00edfica de anticuerpos de polisac\u00e1ridos, la deficiencia selectiva de inmunoglobulina A, la inmunodeficiencia com\u00fan variable y la agammaglobulinemia. M\u00e1s del 70 % de los pacientes ten\u00eda infecciones sinopulmonares. La infecci\u00f3n m\u00e1s frecuente fue la neumon\u00eda, seguida de la otitis media aguda y la sinusitis. El 45 % de los menores de cinco a\u00f1os ten\u00eda un peso adecuado para la talla, el 18 % ten\u00eda riesgo de desnutrici\u00f3n y el 18 % presentaba desnutrici\u00f3n aguda moderada; el 4,5 % sufr\u00eda de obesidad, el 4,5 % ten\u00eda sobrepeso y el 9 % presentaba riesgo de sobrepeso. En los mayores de cinco a\u00f1os, el 54 % ten\u00eda un \u00edndice de masa corporal adecuado, el 22,5 % ten\u00eda sobrepeso, el 9,6 % ten\u00eda riesgo de delgadez y el 9,6 % presentaba delgadez. Se encontr\u00f3 que el riesgo de talla baja y la talla baja fueron m\u00e1s frecuentes que la talla normal, y que los pacientes evaluados presentaron porcentajes de talla baja por encima de los reportados a nivel nacional.Conclusiones. Debido a la epidemia de obesidad infantil, va a ser m\u00e1s frecuente encontrar sobrepeso u obesidad en ni\u00f1os mayores de cinco a\u00f1os, por lo que se considera que la talla baja puede ser un signo de alarma m\u00e1s sensible en pacientes con deficiencias predominantemente de anticuerpos.<\/jats:p>","DOI":"10.7705\/biomedica.7398","type":"journal-article","created":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T15:50:52Z","timestamp":1736437852000},"page":"51-62","update-policy":"https:\/\/doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":1,"title":["Estado nutricional de pacientes pedi\u00e1tricos con deficiencia predominantemente de anticuerpos","Nutritional status in pediatric patients with predominant antibody deficiency"],"prefix":"10.7705","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1478-8401","authenticated-orcid":false,"given":"Lina M.","family":"Casta\u00f1o-Jaramillo","sequence":"first","affiliation":[{"name":"Servicio de Inmunolog\u00eda Cl\u00ednica y Alergia Pedi\u00e1trica, HOMI Fundaci\u00f3n Hospital Pedi\u00e1trico de La Misericordia, Bogot\u00e1, D. C., Colombia"},{"name":"Servicio de Inmunolog\u00eda Cl\u00ednica y Alergia Pedi\u00e1trica, HOMI Fundaci\u00f3n Hospital Pedi\u00e1trico de La Misericordia, Bogot\u00e1, D. C., Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1888-7370","authenticated-orcid":false,"given":"Olga","family":"Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Servicio de Pediatr\u00eda, HOMI Fundaci\u00f3n Hospital Pedi\u00e1trico de La Misericordia, Bogot\u00e1, D. C., Colombia"},{"name":"Servicio de Pediatr\u00eda, HOMI Fundaci\u00f3n Hospital Pedi\u00e1trico de La Misericordia, Bogot\u00e1, D. C., Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2936-3679","authenticated-orcid":false,"given":"Natalia","family":"V\u00e9lez-Tirado","sequence":"additional","affiliation":[{"name":"Servicio de Inmunolog\u00eda Cl\u00ednica y Alergia Pedi\u00e1trica, HOMI Fundaci\u00f3n Hospital Pedi\u00e1trico de La Misericordia, Bogot\u00e1, D. C., Colombia"},{"name":"Servicio de Inmunolog\u00eda Cl\u00ednica y Alergia Pedi\u00e1trica, HOMI Fundaci\u00f3n Hospital Pedi\u00e1trico de La Misericordia, Bogot\u00e1, D. C., Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4444","published-online":{"date-parts":[[2024,12,23]]},"reference":[{"key":"141732","doi-asserted-by":"crossref","unstructured":"Tangye SG, Al-Herz W, Bousfiha A, Cunningham-Rundles C, Franco JL, Holland SM, et al. 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