{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T13:50:12Z","timestamp":1773323412096,"version":"3.50.1"},"reference-count":16,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"3","license":[{"start":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T00:00:00Z","timestamp":1754870400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T00:00:00Z","timestamp":1754870400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["Biomed."],"abstract":"<jats:p>Se trata de una mujer de 28 a\u00f1os que, desde hac\u00eda cinco a\u00f1os, presentaba un n\u00f3dulo asintom\u00e1tico de crecimiento lento y de 10 mm de di\u00e1metro en el muslo derecho, el cual cl\u00ednicamente parec\u00eda corresponder a un dermatofibroma o a un queloide.El n\u00f3dulo se extirp\u00f3 y la histopatolog\u00eda demostr\u00f3 prominentes granulomas d\u00e9rmicos ricos en c\u00e9lulas gigantes, con ocasionales abscesos diminutos y con presencia de abundantes levaduras pigmentadas, de pared oscura, algunas en cadenas, e hifas tabicadas o septadas, de pared negruzca, que inicialmente sugirieron cromoblastomicosis. La abundancia de hifas moniliformes, en cadenas lineales, permitieron concluir que se trataba de una feohifomicosis cut\u00e1nea, sin penetraci\u00f3n a la hipodermis.Se resaltan la cronicidad de la afecci\u00f3n, su forma localizada y la prominencia de granulomas ricos en c\u00e9lulas gigantes, sin abundancia de abscesos. Se desconoce la evoluci\u00f3n de la paciente ya que no regres\u00f3 a control.<\/jats:p>","DOI":"10.7705\/biomedica.7407","type":"journal-article","created":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T18:50:07Z","timestamp":1755283807000},"page":"344-349","update-policy":"https:\/\/doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":0,"title":["N\u00f3dulo cut\u00e1neo de feohifomicosis en una mujer joven","Pheohyphomycosis skin nodule in a young woman"],"prefix":"10.7705","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9749-1365","authenticated-orcid":false,"given":"Mar\u00eda Carolina","family":"Rojas","sequence":"first","affiliation":[{"name":"Facultad de Medicina, Universidad de La Sabana, Ch\u00eda, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6055-5639","authenticated-orcid":false,"given":"Karen Viviana","family":"Ar\u00e9valo","sequence":"additional","affiliation":[{"name":"Programa de Dermatolog\u00eda, Centro Dermatol\u00f3gico Federico Lleras Acosta E.S.E., Bogot\u00e1, D. C., Colombia; Programa de Dermatolog\u00eda, Fundaci\u00f3n Universitaria Sanitas, Bogot\u00e1, D. C., Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9603-6881","authenticated-orcid":false,"given":"Gerza\u00edn","family":"Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Facultad de Medicina, Universidad de La Sabana, Ch\u00eda, Colombia; Programa de Dermatolog\u00eda, Centro Dermatol\u00f3gico Federico Lleras Acosta E.S.E., Bogot\u00e1, D. C., Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4444","published-online":{"date-parts":[[2025,8,11]]},"reference":[{"key":"150326","doi-asserted-by":"crossref","unstructured":"1. Rinaldi MG. Phaeohyphomycosis. Dermatol Clin 1996;14:147-53. https:\/\/doi.org\/10.1016\/s0733-8635(05)70335-1","DOI":"10.1016\/S0733-8635(05)70335-1"},{"key":"150327","doi-asserted-by":"crossref","unstructured":"2. De Hoog GS, Queiros-Tellez F, Haase G, Fernandez-Zeppenfeldt G, Angelis AT, et al. Black fungi: Clinical and pathogenic approaches. Med Mycol. 2000;38(Suppl.1):243-50.","DOI":"10.1080\/mmy.38.s1.243.250"},{"key":"150328","unstructured":"3. Ajello L. Phaeohyphomycosis: Definition and etiology, Mycosis. Scientific publication No. 304. Washington, D.C.: Pan American Health Organization; 1986. p. 16-130."},{"key":"150329","doi-asserted-by":"crossref","unstructured":"4. Peltroche-Llacsahuanga H, Schnitzler N, Jentsch S, Platz A, De Hoog GS, Schweitzer KG, et al. Analyses of phagocytosis, evoked oxidative burst, and killing of black yeasts by human neutrophils: A tool for estimating their pathogenicity? Med Mycol 2003;41:7-14. https:\/\/doi.org\/10.1080\/mmy.41.1.7.14","DOI":"10.1080\/mmy.41.1.7.14"},{"key":"150330","doi-asserted-by":"crossref","unstructured":"5. Revankar SG. Phaeohyphomycosis. Infect Dis Clin North Am. 2006;20:609-20. https:\/\/doi.org\/10.1016\/j.idc.2006.06.004","DOI":"10.1016\/j.idc.2006.06.004"},{"key":"150331","doi-asserted-by":"crossref","unstructured":"6. Vitale RG, De Hoog GS. Molecular diversity, new species, and antifungal susceptibilities in the Exophiala spinifera clade. Med Mycol. 2002;40:545-56. https:\/\/doi.org\/10.1080\/mmy.40.6.545.556","DOI":"10.1080\/mmy.40.6.545.556"},{"key":"150332","doi-asserted-by":"crossref","unstructured":"7. Elias Costa MR, Da Silva Lacaz C, Kawasaki M, De Camargos ZP. Conventional versus molecular diagnostic tests. Med Mycol. 2000;38(Suppl.1):139-45.","DOI":"10.1080\/mmy.38.s1.139.145"},{"key":"150333","doi-asserted-by":"crossref","unstructured":"8. Queiros-Tellez F, Nucci M, Lopes CA, Tob\u00f3n A, Restrepo A. Mycoses of implantation in Latin America: An overview of epidemiology, clinical manifestations, diagnosis, and treatment. Med Mycol. 2011;49:225-36. https:\/\/doi.org\/10.3109\/13693786.2010.539631","DOI":"10.3109\/13693786.2010.539631"},{"key":"150334","unstructured":"9. Rippon JW. Faeohifomicosis. En: Tratado de Micolog\u00eda M\u00e9dica. 3a edici\u00f3n. M\u00e9xico, D. F.: McGraw Hill; 1990. p 321-49."},{"key":"150335","unstructured":"10. Bonifaz A. Micolog\u00eda M\u00e9dica B\u00e1sica. 2\u00aa edici\u00f3n. M\u00e9xico, D.F.: M\u00e9ndez Editors; 2003."},{"key":"150336","doi-asserted-by":"crossref","unstructured":"11. Rodr\u00edguez-Toro G, Palencia Y. Esporotricosis. Valor diagn\u00f3stico del cuerpo asteroide. Biom\u00e9dica. 1985;5:41-6. https:\/\/doi.org\/10.7705\/biomedica.v5i1-2.1900","DOI":"10.7705\/biomedica.v5i1-2.1900"},{"key":"150337","doi-asserted-by":"crossref","unstructured":"12. Frasquet-Art\u00e9s JS, Pem\u00e1n J, Blanes M, Hern\u00e1ndez-Porto M, Cano J, et al. Feohifomicosis cerebral: descripci\u00f3n de un caso y revisi\u00f3n de la literatura. Rev Iberoam Micol. 2014;31:197-202. https:\/\/doi.org\/10.1016\/j.riam.2012.12.008","DOI":"10.1016\/j.riam.2012.12.008"},{"key":"150338","doi-asserted-by":"crossref","unstructured":"13. Alayeto Ortega J, Alier Fabreg\u00f3 A, Puig Verdie L, Sorli Redo ML, Horcajada Gallego JP, Portillo Bordonabe ME. Feohifomicosis subcut\u00e1nea causada por Phaeoacremonium parasiticum. Rev Iberoamer Micol. 2015;32:265-8. https:\/\/doi.org\/10.1016\/j.riam.2014.10.004","DOI":"10.1016\/j.riam.2014.10.004"},{"key":"150339","doi-asserted-by":"crossref","unstructured":"14. Scupsky H, Junkins-Hopkins J. Counterfeit pennies: Distinguishing chromoblastomycosis from phaeohyphomycotic infections. Am J. Dermatopatol. 2017;39:485-7. https:\/\/doi.org\/10.1097\/DAD.0000000000000679","DOI":"10.1097\/DAD.0000000000000679"},{"key":"150340","doi-asserted-by":"crossref","unstructured":"15. Fari\u00f1as MC, Fern\u00e1ndez-Sampedro M, Armi\u00f1anzas C. 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