{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T13:47:27Z","timestamp":1773323247414,"version":"3.50.1"},"reference-count":12,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"4","license":[{"start":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T00:00:00Z","timestamp":1758499200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T00:00:00Z","timestamp":1758499200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["Biomed."],"abstract":"<jats:p>Introduction. Vitiligo is an acquired depigmenting skin disorder characterized by achromic macules resulting from the selective destruction of melanocytes. Epidemiological information regarding this condition remains limited in Colombia and Latin America, with prevalence varying across geographical regions.Objective. To estimate the incidence and prevalence of vitiligo in Colombia by age, gender, and region.Materials and methods. A retrospective study was conducted utilizing real-world clinical practice data retrieved from the national registry SISPRO (Sistema de Informaci\u00f3n para la Protecci\u00f3n Social) spanning the period from 2015 to 2022.Results. Over the eight-year follow-up period (2015-2022) in Colombia, 131,494 patients were diagnosed with vitiligo. In 2016, the lowest incidence was observed, with 26 cases per 100,000 inhabitants, whereas in 2019, the highest incidence was recorded at 47 cases per 100,000 inhabitants, representing a difference of 11,175 cases between the two years. Incidence decreased in 2020 to 28.15 cases per 100,000 inhabitants. Prevalence exhibited a linear increase over the years, with the highest rates observed in 2018 and 2019.Conclusions. This study represents the first comprehensive report on epidemiological data concerning individuals with vitiligo in Colombia, and the second in South America. It contributes to the understanding of this condition, revealing an upward trend in incidence and prevalence. These findings also provide insights into primary treatment modalities, which are probably associated with improved case registration by healthcare providers.<\/jats:p>","DOI":"10.7705\/biomedica.7522","type":"journal-article","created":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T21:45:14Z","timestamp":1758836714000},"page":"566-573","update-policy":"https:\/\/doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":0,"title":["Incidence and prevalence of vitiligo by gender and age in the Colombian population","Epidemiolog\u00eda del vitiligo: incidencia y prevalencia por sexo y edad en la poblaci\u00f3n colombiana"],"prefix":"10.7705","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5976-2518","authenticated-orcid":false,"given":"Paola Andrea","family":"Rueda","sequence":"first","affiliation":[{"name":"Facultad de Ciencias de la Salud, Universidad CES, Medell\u00edn, Colombia;\u00a0Departamento de Dermatolog\u00eda, Universidad CES, Medell\u00edn, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8426-8984","authenticated-orcid":false,"given":"Sara","family":"Orozco","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias de la Salud, Universidad CES, Medell\u00edn, Colombia;\u00a0Departamento de Dermatolog\u00eda, Universidad CES, Medell\u00edn, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0113-2684","authenticated-orcid":false,"given":"Juan Ra\u00fal","family":"Castro","sequence":"additional","affiliation":[{"name":"Departamento de Dermatolog\u00eda, Universidad CES, Medell\u00edn, Colombia;\u00a0Departamento de Dermatolog\u00eda, Hospital Universitario Nacional de Colombia, Bogot\u00e1, D. C., Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2209-9972","authenticated-orcid":false,"given":"\u00c1ngela Mar\u00eda","family":"Londo\u00f1o","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias de la Salud, Universidad CES, Medell\u00edn, Colombia;\u00a0Departamento de Dermatolog\u00eda, Universidad CES, Medell\u00edn, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0665-5310","authenticated-orcid":false,"given":"Elsa Mar\u00eda","family":"V\u00e1squez","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias de la Salud, Universidad CES, Medell\u00edn, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1523-4104","authenticated-orcid":false,"given":"Andrea","family":"Arango","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias de la Salud, Universidad CES, Medell\u00edn, Colombia;\u00a0Departamento de Dermatolog\u00eda, Universidad CES, Medell\u00edn, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2418-6159","authenticated-orcid":false,"given":"Carlos Esteban","family":"Builes","sequence":"additional","affiliation":[{"name":"Departamento de Medicina Interna, Universidad de Antioquia, Medell\u00edn, Colombia;\u00a0Departamento de Endocrinolog\u00eda, Hospital Pablo Tob\u00f3n Uribe, Medell\u00edn, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4444","published-online":{"date-parts":[[2025,9,22]]},"reference":[{"key":"153521","doi-asserted-by":"crossref","unstructured":"Zhang Y, Cai Y, Shi M, Jiang S, Cui S, Wu Y, et al. The prevalence of vitiligo: A metaanalysis. PLoS ONE. 216;11:e0163806. https:\/\/doi.org\/10.1371\/journal.pone.0163806","DOI":"10.1371\/journal.pone.0163806"},{"key":"153522","doi-asserted-by":"crossref","unstructured":"Mastacouris N, Strunk A, Garg A. Incidence and prevalence of diagnosed vitiligo according to race and ethnicity, age, and sex in the US. JAMA Dermatol. 2023;159:986. https:\/\/doi.org\/10.1001\/jamadermatol.2023.2162","DOI":"10.1001\/jamadermatol.2023.2162"},{"key":"153523","doi-asserted-by":"crossref","unstructured":"Pandya AG. Commentary on vitiligo patient population and disease burden in France: VIOLIN Study results from the CONSTANCES cohort. Acad Dermatol Venereol. 2023;37:2159-60. https:\/\/doi.org\/10.1111\/jdv.19502","DOI":"10.1111\/jdv.19502"},{"key":"153524","doi-asserted-by":"crossref","unstructured":"Ezzedine K, Seneschal J, Da Silva A, Pr\u00e9aubert N, Lamblin A, Delattre C, et al. Vitiligo patient population and disease burden in France: VIOLIN study results from the CONSTANCES cohort. Acad Dermatol Venereol. 2023;37:2249-58. https:\/\/doi.org\/10.1111\/jdv.19447","DOI":"10.1111\/jdv.19447"},{"key":"153525","doi-asserted-by":"crossref","unstructured":"Cesar Silva De Castro C, Miot HA. Prevalence of vitiligo in Brazil\u2014A population survey. Pigment Cell Melanoma Res. 2018;31:448-50. https:\/\/doi.org\/10.1111\/pcmr.12681","DOI":"10.1111\/pcmr.12681"},{"key":"153526","doi-asserted-by":"crossref","unstructured":"Ray M, Gandhi K, Maughn K, Pandya AG. Diagnosed prevalence and incidence of vitiligo in the United States: Analysis of employer-sponsored insurance claims. JID Innov. 2023;3:100199. https:\/\/doi.org\/10.1016\/j.xjidi.2023.100199","DOI":"10.1016\/j.xjidi.2023.100199"},{"key":"153527","doi-asserted-by":"crossref","unstructured":"Al Hammadi A, Silva De Castro CC, Parmar NV, Ubogui J, Hatatah N, Ahmed HM, et al. Prevalence and burden of vitiligo in Africa, the Middle East, and Latin America. Skin Health Dis. 2024;4:e317. https:\/\/doi.org\/10.1002\/ski2.317","DOI":"10.1002\/ski2.317"},{"key":"153528","doi-asserted-by":"crossref","unstructured":"Londo\u00f1o-Garc\u00eda A, Arango-Salgado A, Orozco-Covarrubias MD, Jansen AM, Rico-Restrepo M, Riviti MC, et al. The landscape of vitiligo in Latin America: A call to action. J Dermatolog Treat. 2023;34:2164171. https:\/\/doi.org\/10.1080\/09546634.2022.2164171","DOI":"10.1080\/09546634.2022.2164171"},{"key":"153529","doi-asserted-by":"crossref","unstructured":"Chang WL, Lee WR, Kuo YC, Huang YH. Vitiligo: An autoimmune skin disease and its immunomodulatory therapeutic intervention. Front Cell Dev Biol. 2021;9:797026. https:\/\/doi.org\/10.3389\/fcell.2021.797026","DOI":"10.3389\/fcell.2021.797026"},{"key":"153530","doi-asserted-by":"crossref","unstructured":"Joge RR, Kathane PU, Joshi SH. Vitiligo: A narrative review article. Cureus. 2022;14:e29307. https:\/\/doi.org\/10.7759\/cureus.29307","DOI":"10.7759\/cureus.29307"},{"key":"153531","doi-asserted-by":"crossref","unstructured":"Ezzedine K, Sheth V, Rodrigues M, Eleftheriadou V, Harris JE, Hamzavi IH, et al. Vitiligo is not a cosmetic disease. J Am Acad Dermatol. 2015;73:883-5. https:\/\/doi.org\/10.1016\/j.jaad.2015.07.039","DOI":"10.1016\/j.jaad.2015.07.039"},{"key":"153532","doi-asserted-by":"crossref","unstructured":"Wong PM, Yang L, Yang L, Wu H, Li W, Ma X, et al. New insight into the role of exosomes in vitiligo. Autoimmun Rev. 2020;19:102664. https:\/\/doi.org\/10.1016\/j.autrev.2020.102664","DOI":"10.1016\/j.autrev.2020.102664"}],"container-title":["Biom\u00e9dica"],"original-title":[],"link":[{"URL":"https:\/\/revistabiomedica.org\/index.php\/biomedica\/article\/download\/7522\/5775","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistabiomedica.org\/index.php\/biomedica\/article\/download\/7522\/5882","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistabiomedica.org\/index.php\/biomedica\/article\/download\/7522\/5775","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T21:36:39Z","timestamp":1773264999000},"score":1,"resource":{"primary":{"URL":"https:\/\/revistabiomedica.org\/index.php\/biomedica\/article\/view\/7522"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,22]]},"references-count":12,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,9,22]]}},"URL":"https:\/\/doi.org\/10.7705\/biomedica.7522","relation":{},"ISSN":["2590-7379","0120-4157"],"issn-type":[{"value":"2590-7379","type":"electronic"},{"value":"0120-4157","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9,22]]},"assertion":[{"value":"2025-09-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}},{"value":"Yes","order":0,"name":"peer_reviewed","label":"Peer Reviewed","group":{"name":"peer_review","label":"Peer Review"}},{"value":"Instituto Nacional de Salud","name":"publisher","label":"This article is maintained by"},{"value":"Biomedica","name":"journaltitle","label":"Journal Title"},{"value":"Art\u00edculos originales","name":"content_type","label":"Content Type"}]}}