{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:17:55Z","timestamp":1773361075912,"version":"3.50.1"},"reference-count":29,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"2","license":[{"start":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T00:00:00Z","timestamp":1748563200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T00:00:00Z","timestamp":1748563200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100002753","name":"Universidad Nacional de Colombia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002753","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002753","name":"Universidad Nacional de Colombia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002753","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["Biomed."],"abstract":"<jats:p>Introducci\u00f3n. La estadificaci\u00f3n del c\u00e1ncer de pr\u00f3stata es necesaria para determinar la extensi\u00f3n tumoral. En los \u00faltimos a\u00f1os, han surgido modalidades de imagen nuevas y m\u00e1s precisas que han mejorado el manejo de los pacientes. Las gu\u00edas de pr\u00e1ctica cl\u00ednica son una herramienta importante para implementar los hallazgos de la investigaci\u00f3n cl\u00ednica basada en evidencia de alta calidad.Objetivo. Revisar y evaluar la calidad de la evidencia de las gu\u00edas de estadificaci\u00f3n del c\u00e1ncer de pr\u00f3stata mediante la herramienta AGREE II.Materiales y m\u00e9todos. Se realiz\u00f3 una b\u00fasqueda sistem\u00e1tica en las bases de datos PubMed, BiGG y Epistemonikos. Tambi\u00e9n, se exploraron repositorios y sitios web de gu\u00edas de pr\u00e1ctica cl\u00ednica para identificar recomendaciones GRADE de estadificaci\u00f3n del c\u00e1ncer de pr\u00f3stata publicadas en los \u00faltimos cinco a\u00f1os. La calidad metodol\u00f3gica de las gu\u00edas se evalu\u00f3 utilizando la herramienta AGREE II. Se resumieron las recomendaciones y la certeza de la evidencia.Resultados. Siete gu\u00edas cumplieron con los criterios de inclusi\u00f3n. Se hizo un an\u00e1lisis narrativo de las recomendaciones y un mapeo de la evidencia. El dominio \u201cclaridad de presentaci\u00f3n\u201d tuvo la puntuaci\u00f3n m\u00e1s alta (media = 71,59 %), mientras que \u201caplicabilidad\u201d tuvo la puntuaci\u00f3n m\u00e1s baja (media = 45,15 %). Cinco gu\u00edas cumplieron con el punto corte propuesto y conten\u00edan recomendaciones de estadificaci\u00f3n y diagn\u00f3stico.Conclusiones. Se observ\u00f3 una heterogeneidad significativa en la calidad metodol\u00f3gica de las gu\u00edas incluidas; se encontraron falencias comunes relacionadas con la aplicabilidad y la participaci\u00f3n de las partes interesadas.<\/jats:p>","DOI":"10.7705\/biomedica.7653","type":"journal-article","created":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T10:31:13Z","timestamp":1749033073000},"page":"286-296","update-policy":"https:\/\/doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":0,"title":["Revisi\u00f3n sistem\u00e1tica de las recomendaciones GRADE para la estadificaci\u00f3n del c\u00e1ncer de pr\u00f3stata","Systematic critical appraisal of GRADE recommendations for prostate cancer staging"],"prefix":"10.7705","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-7302-8805","authenticated-orcid":false,"given":"Dayana","family":"S\u00e1enz","sequence":"first","affiliation":[{"name":"Unidad de Urolog\u00eda, Departamento de Cirug\u00eda, Facultad de Medicina, Universidad Nacional de Colombia, Bogota\u0301, D. C., Colombia;\u00a0Grupo de Investigaci\u00f3n e Innovaci\u00f3n en Urolog\u00eda, Universidad Nacional de Colombia, Bogota\u0301, D. C., Colombia"},{"name":"Unidad de Urolog\u00eda, Departamento de Cirug\u00eda, Facultad de Medicina, Universidad Nacional de Colombia, Bogota\u0301, D. C., Colombia;\u00a0Grupo de Investigaci\u00f3n e Innovaci\u00f3n en Urolog\u00eda, Universidad Nacional de Colombia, Bogota\u0301, D. C., Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0412-5540","authenticated-orcid":false,"given":"Ana Marcela","family":"Torres","sequence":"additional","affiliation":[{"name":"Instituto de Investigaciones Cl\u00ednicas, Facultad de Medicina, Universidad Nacional de Colombia, Bogota\u0301, D. C., Colombia"},{"name":"Instituto de Investigaciones Cl\u00ednicas, Facultad de Medicina, Universidad Nacional de Colombia, Bogota\u0301, D. C., Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7411-5853","authenticated-orcid":false,"given":"Rodrigo","family":"Pardo","sequence":"additional","affiliation":[{"name":"Instituto de Investigaciones Cl\u00ednicas, Facultad de Medicina, Universidad Nacional de Colombia, Bogota\u0301, D. C., Colombia"},{"name":"Instituto de Investigaciones Cl\u00ednicas, Facultad de Medicina, Universidad Nacional de Colombia, Bogota\u0301, D. C., Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0864-421X","authenticated-orcid":false,"given":"Wilfredo","family":"Donoso","sequence":"additional","affiliation":[{"name":"Unidad de Urolog\u00eda, Departamento de Cirug\u00eda, Facultad de Medicina, Universidad Nacional de Colombia, Bogota\u0301, D. C., Colombia; Grupo de Investigaci\u00f3n e Innovaci\u00f3n en Urolog\u00eda, Universidad Nacional de Colombia, Bogota\u0301, D. C., Colombia"},{"name":"Unidad de Urolog\u00eda, Departamento de Cirug\u00eda, Facultad de Medicina, Universidad Nacional de Colombia, Bogota\u0301, D. C., Colombia; Grupo de Investigaci\u00f3n e Innovaci\u00f3n en Urolog\u00eda, Universidad Nacional de Colombia, Bogota\u0301, D. C., Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4444","published-online":{"date-parts":[[2025,5,30]]},"reference":[{"key":"148243","doi-asserted-by":"crossref","unstructured":"1. Han M, Partin AW, Piantadosi S, Epstein JI, Walsh PC. Era specific biochemical recurrence free survival following radical prostatectomy for clinically localized prostate cancer. J Urol. 2001;166:416-9. https:\/\/doi.org\/10.1016\/S0022-5347(05)65955-1","DOI":"10.1016\/S0022-5347(05)65955-1"},{"key":"148244","doi-asserted-by":"crossref","unstructured":"2. Siegel RL, Miller KD, Wagle NS, Ahmedin J. Cancer statistics, 2023. 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Biochemical outcome after radical prostatectomy, external beam radiation therapy, or interstitial radiation therapy for clinically localized prostate cancer. JAMA.1998;280:969-74. https:\/\/doi.org\/10.1001\/jama.280.11.969","DOI":"10.1001\/jama.280.11.969"},{"key":"148249","doi-asserted-by":"crossref","unstructured":"7. Mottet N, Cornford P, van den Bergh R, Briers E, Eberli D, van den Broeck T, et al. EAU-EANM-ESTRO-ESUR-SIOG Guidelines on Prostate Cancer-2020 Update. Part 1: Screening, diagnosis, and local treatment with curative intent. Eur Urol. 2021;79:243-62. https:\/\/doi.org\/10.1016\/j.eururo.2020.09.042","DOI":"10.1016\/j.eururo.2020.09.042"},{"key":"148250","doi-asserted-by":"crossref","unstructured":"8. Graham R, Mancher M, Wolman DM, Greenfield S, Steinberg E. Clinical practice guidelines we can trust. Washington, D.C.: National Academies Press; 2011. p. 4-266. https:\/\/doi.org\/10.17226\/13058","DOI":"10.17226\/13058"},{"key":"148251","doi-asserted-by":"crossref","unstructured":"9. Cates JR, Young DN, Guerriero DJ, Jahn WT, Armine JP, Korbett AB, et al. Evaluating the quality of clinical practice guidelines. J Manipulative Physiol Ther. 2001;24:170-6. https:\/\/doi.org\/10.1016\/S0161-4754(01)19243-2","DOI":"10.1016\/S0161-4754(01)19243-2"},{"key":"148252","doi-asserted-by":"crossref","unstructured":"10. Brouwers MC, Kho ME, Browman GP, Burgers JS, Cluzeau F, Feder G, et al. AGREE II: Advancing guideline development, reporting, and evaluation in health care. CMAJ. 2010;182:E839-42. https:\/\/doi.org\/10.1503\/cmaj.090449","DOI":"10.1503\/cmaj.090449"},{"key":"148253","unstructured":"11. AGREE Next Steps Consortium. The AGREE II Instrument. Accessed: December 18, 2023. 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Methodological quality of clinical practice guidelines with physical activity recommendations for people diagnosed with cancer: A systematic critical appraisal using the AGREE II tool. PLoS ONE. 2019;14:e0214846. https:\/\/doi.org\/10.1371\/journal.pone.0214846","DOI":"10.1371\/journal.pone.0214846"},{"key":"148259","doi-asserted-by":"crossref","unstructured":"17. Zhou X, Yang Y, Li C, Gu S, Hou W, Lai X, et al. What information can we gain from the quality appraisal of guidelines with physical activity recommendations for cancer patients? A systematic review using the AGREE II and AGREE-REX tools. Support Care Cancer. 2023;31:97. https:\/\/doi.org\/10.1007\/s00520-022-07567-5","DOI":"10.1007\/s00520-022-07567-5"},{"key":"148260","doi-asserted-by":"crossref","unstructured":"18. Bekelman JE, Rumble RB, Chen RC, Pisansky TM, Finelli A, Feifer A, et al. Clinically localized prostate cancer: ASCO clinical practice guideline endorsement of an American Urological Association\/American Society for Radiation Oncology\/Society of Urologic Oncology guideline. J Clin Oncol. 2018;36:3251-8. https:\/\/doi.org\/10.1200\/JCO.18.00606","DOI":"10.1200\/JCO.18.00606"},{"key":"148261","doi-asserted-by":"crossref","unstructured":"19. Parker C, Castro E, Fizazi K, Heidenreich A, Ost P, Procopio G, et al. Prostate cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment, and follow-up. Ann Oncol. 2020;31:1119-34. https:\/\/doi.org\/10.1016\/j.annonc.2020.06.011","DOI":"10.1016\/j.annonc.2020.06.011"},{"key":"148262","unstructured":"20. National Institute for Health and Care Excellence - NICE. Prostate cancer: Diagnosis and management. Accessed: October 15, 2023. Available at: www.nice.org.uk\/guidance\/ng13"},{"key":"148263","doi-asserted-by":"crossref","unstructured":"21. 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