{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T03:16:13Z","timestamp":1783048573425,"version":"3.54.6"},"reference-count":30,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"2","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["Biomed."],"abstract":"<jats:p>La infecci\u00f3n por HIV es un factor de riesgo para el desarrollo de enfermedades cardiovasculares, incluyendo los accidentes cerebrovasculares isqu\u00e9micos.Se presenta el caso de un hombre de 27 a\u00f1os con sida, con un accidente cerebrovascular isqu\u00e9mico de la arteria cerebral media izquierda. Los ex\u00e1menes de laboratorio confirmaron el diagn\u00f3stico de neuros\u00edfilis y, adem\u00e1s, confirmaron la existencia de anticuerpos antifosfol\u00edpidos. Siete meses despu\u00e9s del tratamiento de la neuros\u00edfilis, de la anticoagulaci\u00f3n y de la terapia antirretroviral, se confirm\u00f3 la persistencia de anticuerpos antifosfol\u00edpidos.El enfoque diagn\u00f3stico de un accidente cerebral vascular en personas con HIV es un reto, ya que puede asociarse a m\u00faltiples etiolog\u00edas. La relevancia de los anticuerpos antifosfol\u00edpidos en estos pacientes es tema de debate y debe tenerse en cuenta seg\u00fan el cuadro cl\u00ednico.<\/jats:p>","DOI":"10.7705\/biomedica.7830","type":"journal-article","created":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T17:11:52Z","timestamp":1782321112000},"page":"179-186","update-policy":"https:\/\/doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":0,"title":["Accidente cerebrovascular isqu\u00e9mico en un paciente VIH: neuros\u00edfilis y s\u00edndrome antifosfol\u00edpidos","Ischemic cerebrovascular accident in an HIV patient: Neurosyphilis and antiphospholipid syndrome"],"prefix":"10.7705","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6810-8064","authenticated-orcid":false,"given":"Sebasti\u00e1n","family":"Ayala","sequence":"first","affiliation":[{"name":"Departamento de Medicina Interna, Cl\u00ednica Imbanaco, Cali, Colombia"},{"name":"Departamento de Medicina Interna, Cl\u00ednica Imbanaco, Cali, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-7126-1951","authenticated-orcid":false,"given":"Mar\u00eda del Mar","family":"Ortiz","sequence":"additional","affiliation":[{"name":"Departamento de Hospitalizaci\u00f3n, Cl\u00ednica Imbanaco, Cali, Colombia"},{"name":"Departamento de Hospitalizaci\u00f3n, Cl\u00ednica Imbanaco, Cali, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8476-5956","authenticated-orcid":false,"given":"Mar\u00eda Carolina","family":"V\u00e1squez","sequence":"additional","affiliation":[{"name":"Departamento de Hospitalizaci\u00f3n, Cl\u00ednica Imbanaco, Cali, Colombia"},{"name":"Departamento de Hospitalizaci\u00f3n, Cl\u00ednica Imbanaco, Cali, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4444","published-online":{"date-parts":[[2026,6,1]]},"reference":[{"key":"164338","doi-asserted-by":"crossref","unstructured":"Guti\u00e9rrez J, Albuquerque AL, Falzon L. 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