{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T19:40:44Z","timestamp":1783021244370,"version":"3.54.6"},"reference-count":26,"publisher":"Instituto Nacional de Salud (Colombia)","issue":"Sp. 1","license":[{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["revistabiomedica.org"],"crossmark-restriction":false},"short-container-title":["Biomed."],"abstract":"<jats:p>Introducci\u00f3n. Las infecciones por estreptococos del grupo viridans en pacientes oncol\u00f3gicos pueden ser graves, con una gran mortalidad.Objetivo. Describir las caracter\u00edsticas cl\u00ednicas, microbiol\u00f3gicas y evolutivas de los pacientes pedi\u00e1tricos con bacteriemia por estreptococos del grupo viridans y leucemia aguda en un hospital de alta complejidad e identificar las variables asociadas con la recurrencia.Materiales y m\u00e9todos. Se trata de un estudio retrospectivo de cohorte. Se incluyeron 108 pacientes de 1 mes hasta 18 a\u00f1os con leucemia aguda y con bacteriemia por estreptococos del grupo viridans entre el 2016 y el 2022. Se describieron las caracter\u00edsticas de la cohorte y se hizo un an\u00e1lisis univariado, comparando las caracter\u00edsticas de los pacientes que presentaron un primer o \u00fanico episodio de bacteriemia con las de aquellos con recurrencia.Resultados. Se estudiaron 108 episodios correspondientes a 85 (79 %) pacientes que presentaron un primer o \u00fanico episodio y a 23 (21 %) que presentaron recurrencias. La mediana de edad fue de 68 meses. Las especies m\u00e1s frecuente fueron Streptococcus mitis y S. oralis en ambos grupos. Se asoci\u00f3 con recurrencia de la bacteriemia: el uso de antibi\u00f3ticos en los 30 d\u00edas previos [n = 20 (87 %) vs. n = 52 (61 %), p = 0,03], una mayor duraci\u00f3n del tratamiento antibi\u00f3tico previo, el uso de carbapenem, la gastroenteritis aguda como foco cl\u00ednico de infecci\u00f3n y la etapa de consolidaci\u00f3n de la quimioterapia.Conclusiones. La bacteriemia por estreptococos del grupo viridans predomin\u00f3 en ni\u00f1os con leucemia mieloide aguda. El 21 % fueron recurrencias. La recurrencia se asoci\u00f3 con el uso previo de antibi\u00f3ticos, la gastroenteritis como foco cl\u00ednico y la etapa de consolidaci\u00f3n de la quimioterapia.<\/jats:p>","DOI":"10.7705\/biomedica.8038","type":"journal-article","created":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T14:54:25Z","timestamp":1783004065000},"page":"88-98","update-policy":"https:\/\/doi.org\/10.7705\/crossmark","source":"Crossref","is-referenced-by-count":0,"title":["Bacteriemia por estreptococos del grupo viridans en ni\u00f1os con leucemia: epidemiolog\u00eda y variables asociadas con la recurrencia","Bacteremia by viridans group streptococci in children with leukemia: Epidemiology and variables associated with recurrence"],"prefix":"10.7705","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-9931-4820","authenticated-orcid":false,"given":"Mar\u00eda Emilia","family":"Padilla","sequence":"first","affiliation":[{"name":"Servicio de Epidemiolog\u00eda e Infectolog\u00eda, Hospital Nacional de Pediatr\u00eda S.A.M.I.C. \u201cProfesor Dr. Juan P. 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