{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T16:29:09Z","timestamp":1792513749318,"version":"4.5.0"},"reference-count":57,"publisher":"PeerJ","license":[{"start":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T00:00:00Z","timestamp":1731369600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:sec>\n<jats:title>Background<\/jats:title>\n<jats:p>In recent years, artificial intelligence (AI) and deep learning (DL) have made a considerable impact in dentistry, specifically in advancing image processing algorithms for detecting caries from radiographical images. Despite this progress, there is still a lack of data on the effectiveness of these algorithms in accurately identifying caries. This study provides an overview aimed at evaluating and comparing reviews that focus on the detection of <jats:italic>dental caries (DC)<\/jats:italic> using DL algorithms from 2D radiographs.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Materials and Methods<\/jats:title>\n<jats:p>This comprehensive umbrella review adhered to the \u201cReporting guideline for overviews of reviews of healthcare interventions\u201d (PRIOR). Specific keywords were generated to assess the accuracy of AI and DL algorithms in detecting DC from radiographical images. To ensure the highest quality of research, thorough searches were performed on PubMed\/Medline, Web of Science, Scopus, and Embase. Additionally, bias in the selected articles was rigorously assessed using the Joanna Briggs Institute (JBI) tool.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>In this umbrella review, seven systematic reviews (SRs) were assessed from a total of 77 studies included. Various DL algorithms were used across these studies, with conventional neural networks and other techniques being the predominant methods for detecting DC. The SRs included in the study examined 24 original articles that used 2D radiographical images for caries detection. Accuracy rates varied between 0.733 and 0.986 across datasets ranging in size from 15 to 2,500 images.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Conclusion<\/jats:title>\n<jats:p>The advancement of DL algorithms in detecting and predicting DC through radiographic imaging is a significant breakthrough. These algorithms excel in extracting subtle features from radiographic images and applying machine learning techniques to achieve highly accurate predictions, often outperforming human experts. This advancement holds immense potential to transform diagnostic processes in dentistry, promising to considerably improve patient outcomes.<\/jats:p>\n<\/jats:sec>","DOI":"10.7717\/peerj-cs.2371","type":"journal-article","created":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T08:57:34Z","timestamp":1731401854000},"page":"e2371","source":"Crossref","is-referenced-by-count":17,"title":["Comparative analysis of deep learning algorithms for dental caries detection and prediction from radiographic images: a comprehensive umbrella review"],"prefix":"10.7717","volume":"10","author":[{"given":"Mahmood","family":"Dashti","sequence":"first","affiliation":[{"name":"Dentofacial Deformities Research Center, Research Institute of Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jimmy","family":"Londono","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, Dental College of 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