{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:17:16Z","timestamp":1790666236217,"version":"4.1.0"},"reference-count":58,"publisher":"PeerJ","license":[{"start":{"date-parts":[[2021,12,13]],"date-time":"2021-12-13T00:00:00Z","timestamp":1639353600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      In the face of ongoing climate warming, vector-borne diseases are expected to increase in Europe, including tick-borne diseases (TBD). The most abundant tick-borne diseases in Germany are Tick-Borne Encephalitis (TBE) and Lyme Borreliosis (LB), with\n                      <jats:italic>Ixodes ricinus<\/jats:italic>\n                      as the main vector.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this study, we display and compare the spatial and temporal patterns of reported cases of human TBE and LB in relation to some associated factors. The comparison may help with the interpretation of observed spatial and temporal patterns.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The spatial patterns of reported TBE cases show a clear and consistent pattern over the years, with many cases in the south and only few and isolated cases in the north of Germany. The identification of spatial patterns of LB disease cases is more difficult due to the different reporting practices in the individual federal states. Temporal patterns strongly fluctuate between years, and are relatively synchronized between both diseases, suggesting common driving factors. Based on our results we found no evidence that weather conditions affect the prevalence of both diseases. Both diseases show a gender bias with LB bing more commonly diagnosed in females, contrary to TBE being more commonly diagnosed in males.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>For a further investigation of of the underlying driving factors and their interrelations, longer time series as well as standardised reporting and surveillance system would be required.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.7717\/peerj.12422","type":"journal-article","created":{"date-parts":[[2021,12,13]],"date-time":"2021-12-13T03:48:57Z","timestamp":1639367337000},"page":"e12422","source":"Crossref","is-referenced-by-count":8,"title":["Spatial and temporal distribution patterns of tick-borne diseases (Tick-borne Encephalitis and Lyme Borreliosis) in Germany"],"prefix":"10.7717","volume":"9","author":[{"given":"Sarah","family":"Cunze","sequence":"first","affiliation":[{"name":"Institute of Ecology, Evolution and Diversity, Johann Wolfgang Goethe Universit\u00e4t Frankfurt am Main, Frankfurt am Main, Hesse, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustav","family":"Glock","sequence":"additional","affiliation":[{"name":"Institute of Ecology, Evolution and Diversity, Johann Wolfgang Goethe Universit\u00e4t Frankfurt am Main, Frankfurt am Main, Hesse, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sven","family":"Klimpel","sequence":"additional","affiliation":[{"name":"Institute of Ecology, Evolution and Diversity, Johann Wolfgang Goethe Universit\u00e4t Frankfurt am Main, Frankfurt am Main, Hesse, Germany"},{"name":"Biodiversity and Climate Research Centre, Senckenberg Nature Research Society, Frankfurt am Main, Hesse, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4443","published-online":{"date-parts":[[2021,12,13]]},"reference":[{"issue":"10","key":"10.7717\/peerj.12422\/ref-1","first-page":"S. 1","article-title":"Surveillance for Lyme disease\u2013United States, 1992-2006","volume":"57","author":"Bacon","year":"2008","journal-title":"Morbidity and mortality weekly report. 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