{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T12:34:53Z","timestamp":1769344493826,"version":"3.49.0"},"reference-count":123,"publisher":"PeerJ","license":[{"start":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T00:00:00Z","timestamp":1653955200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Australian Government Research Training Program Scholarship"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p><jats:italic>Helicobacter pylori<\/jats:italic>(<jats:italic>H. pylori<\/jats:italic>), a bacterium implicated in the development of peptic ulcer and gastric cancer, is estimated to infect around half the world\u2019s population. Its prevalence in Australia is unclear. This scoping review aimed to evaluate all Australian literature providing estimates of the prevalence of<jats:italic>H. pylori<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Australian studies examining<jats:italic>H. pylori<\/jats:italic>prevalence from 1982 onwards were eligible for inclusion. Medline, Embase and Scopus databases, and grey literature sources, were searched. Two independent reviewers undertook a two-stage screening process. Data were extracted by two independent reviewers using a pre-specified template.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 444 identified studies, 75 were included in the review.<jats:italic>H. pylori<\/jats:italic>prevalence in Australian population-based studies (<jats:italic>n<\/jats:italic>\u00a0=\u00a08) ranged from 38.0% in 1991 to 15.1% in 2002; however, estimated prevalence across all non-clinical population studies in diverse sub-groups (<jats:italic>n<\/jats:italic>\u00a0=\u00a029) has varied dramatically. Decreased prevalence has been more marked in populations with gastrointestinal symptoms and conditions compared to non-clinical populations. Data on<jats:italic>H. pylori<\/jats:italic>prevalence in vulnerable populations are lacking.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This is the first scoping review of Australian studies reporting<jats:italic>H. pylori<\/jats:italic>prevalence. A wide range of study designs, population groups, geographic regions, and diagnostic methods was included, involving data collected over a 50-year period (1969 to 2018). The summary of<jats:italic>H. pylori<\/jats:italic>prevalence estimates over time in this review points to a decrease in prevalence in Australia, particularly among populations with gastrointestinal symptoms and illnesses; however, it is unknown whether there is inequity in prevalence trends across vulnerable sub-groups of the Australian population. Future research and interventions supporting the health and wellbeing of vulnerable populations is required to ensure equitable health gains are made for all.<\/jats:p><\/jats:sec>","DOI":"10.7717\/peerj.13430","type":"journal-article","created":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T08:08:10Z","timestamp":1653984490000},"page":"e13430","source":"Crossref","is-referenced-by-count":9,"title":["Epidemiology of<i>Helicobacter pylori<\/i>in Australia: a scoping review"],"prefix":"10.7717","volume":"10","author":[{"given":"Jillian","family":"Congedi","sequence":"first","affiliation":[{"name":"UniSA Allied Health and Human Performance, Australian Centre for Precision Health, University of South Australia, Adelaide, South Australia, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Craig","family":"Williams","sequence":"additional","affiliation":[{"name":"UniSA Clinical and Health Sciences, Australian Centre for Precision Health, University of South Australia, Adelaide, South Australia, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine L.","family":"Baldock","sequence":"additional","affiliation":[{"name":"UniSA Allied Health and Human Performance, Australian Centre for Precision Health, University of South Australia, Adelaide, South Australia, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4443","published-online":{"date-parts":[[2022,5,31]]},"reference":[{"issue":"2","key":"10.7717\/peerj.13430\/ref-1","doi-asserted-by":"publisher","first-page":"e12360","DOI":"10.1111\/hel.12360","article-title":"Prevalence of Helicobacter pylori infection in newly arrived refugees attending the migrant health service, South Australia","volume":"22","author":"Abdul\u00a0Rahim","year":"2017","journal-title":"Helicobacter"},{"issue":"11","key":"10.7717\/peerj.13430\/ref-2","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1093\/aje\/kwj129","article-title":"Peptic ulcer 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