{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T12:54:31Z","timestamp":1782996871313,"version":"3.54.5"},"reference-count":37,"publisher":"PeerJ","license":[{"start":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T00:00:00Z","timestamp":1655251200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:sec>\n<jats:title>Objective<\/jats:title>\n<jats:p>The aim of this study was to investigate the effect of skeletal sarcopenia on the prognosis of intertrochanteric fracture in the elderly.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>We collected information on 144 patients with femoral intertrochanteric fracture (FIF). The influence of sarcopenia on the chance of death was determined using binary Probit regression analysis. For additional analysis, the Chow test was utilized to select the best distinguishing node in the instrumental activities of daily living (IADL) score. We looked for characteristics that were linked to a higher probability of death and a poor IADL outcome within 1 year. The data collected above were analyzed using logistic regression analysis. The internal calibration degree and model validity were assessed by GiViTI calibration.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>Sarcopenia, EuroQol-5D 1 month score, age, gender, and hypertension were identified as risk factors for death in older patients with FIF within a year by logistic regression analysis. Sarcopenia, psychotropics, BMI, and length of hospital stay were all found to be risk factors for poor IADL outcomes (<jats:italic>P<\/jats:italic> &lt; 0.1). The calibration curves indicated that the anticipated and actual probabilities of these two models were very close. The study\u2019s reliability coefficient was 0.671, showing a satisfactory level of reliability.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Conclusion<\/jats:title>\n<jats:p>In elderly patients with FIF, sarcopenia, EuroQol-5D score, age, gender, and hypertension were risk factors for death; sarcopenia, hospital stay length, BMI were risk factors for poor quality of life.<\/jats:p>\n<\/jats:sec>","DOI":"10.7717\/peerj.13445","type":"journal-article","created":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T08:58:44Z","timestamp":1655283524000},"page":"e13445","source":"Crossref","is-referenced-by-count":6,"title":["Impact of sarcopenia on intertrochanteric femoral fracture in the elderly"],"prefix":"10.7717","volume":"10","author":[{"given":"Shunli","family":"Jiang","sequence":"first","affiliation":[{"name":"The Affiliated Lianyungang Oriental Hospital, Kangda College of Nanjng Medical University, Lianyungang, Jiangsu Province, China"},{"name":"The Affiliated Lianyungang Oriental Hospital, Xuzhou Medical University, Lianyungang, Jiangsu Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Ding","sequence":"additional","affiliation":[{"name":"Wafangdian Central Hospital, Dalian, Liaoning province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lixing","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Langfang People\u2019s Hospital, Langfang, Hebei Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4443","published-online":{"date-parts":[[2022,6,15]]},"reference":[{"key":"10.7717\/peerj.13445\/ref-1","doi-asserted-by":"publisher","first-page":"326","DOI":"10.3389\/fendo.2018.00326","article-title":"Vitamin D level and activities of daily living in octogenarians: cross-sectional study","volume":"9","author":"Alekna","year":"2018","journal-title":"Frontiers in Endocrinology"},{"key":"10.7717\/peerj.13445\/ref-2","first-page":"1","article-title":"Treatment of common hip fractures","volume":"184","author":"Butler","year":"2009","journal-title":"Evidence Report\/Technology Assessment"},{"issue":"6","key":"10.7717\/peerj.13445\/ref-3","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1007\/s00256-017-2848-6","article-title":"Effect of sarcopenia on clinical and surgical outcome in elderly patients with proximal femur fractures","volume":"47","author":"Chang","year":"2018","journal-title":"Skeletal Radiology"},{"issue":"3","key":"10.7717\/peerj.13445\/ref-4","doi-asserted-by":"publisher","first-page":"e8793","DOI":"10.7717\/peerj.8793","article-title":"Predicting the risk of sarcopenia in elderly patients with patellar fracture: development and assessment of a new predictive nomogram","volume":"8","author":"Chen","year":"2020","journal-title":"PeerJ"},{"issue":"2","key":"10.7717\/peerj.13445\/ref-5","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.jamda.2013.11.025","article-title":"Sarcopenia in Asia: consensus report of the Asian Working Group for Sarcopenia","volume":"15","author":"Chen","year":"2014","journal-title":"Journal of the American Medical Directors Association"},{"key":"10.7717\/peerj.13445\/ref-6","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1093\/ageing\/afq034","article-title":"Sarcopenia: European consensus on definition and diagnosis: report of the European working group on sarcopenia in older people","volume":"39","author":"Cruz-Jentoft","year":"2010","journal-title":"Age and Ageing"},{"issue":"1","key":"10.7717\/peerj.13445\/ref-7","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1093\/ageing\/afy169","article-title":"Writing Group for the European Working Group on Sarcopenia in Older People 2 (EWGSOP2), and the Extended Group for EWGSOP2, Sarcopenia: revised European consensus on definition and diagnosis","volume":"48","author":"Cruz-Jentoft","year":"2019","journal-title":"Age and Ageing"},{"issue":"4","key":"10.7717\/peerj.13445\/ref-8","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1007\/s40520-014-0306-z","article-title":"Presarcopenia and sarcopenia in hip-fracture women: prevalence and association with ability to function in activities of daily living","volume":"27","author":"Di Monaco","year":"2015","journal-title":"Aging Clinical and Experimental Research"},{"issue":"4","key":"10.7717\/peerj.13445\/ref-9","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1007\/s00038-012-0416-3","article-title":"The reliability of a two-item scale: pearson, cronbach, or spearman-brown?","volume":"58","author":"Eisinga","year":"2013","journal-title":"International Journal of Public Health"},{"issue":"3","key":"10.7717\/peerj.13445\/ref-10","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/0168-8510(90)90421-9","article-title":"EuroQol-a new facility for the measurement of health-related quality of life","volume":"16","author":"EuroQol Group","year":"1990","journal-title":"Health Policy"},{"key":"10.7717\/peerj.13445\/ref-11","doi-asserted-by":"publisher","first-page":"637","DOI":"10.2147\/CLEP.S321763","article-title":"Development and validation of a clinical prognostic risk score to predict early neonatal mortality, Ethiopia: a receiver operating characteristic curve analysis","volume":"13","author":"Gebremariam","year":"2021","journal-title":"Clinical Epidemiology"},{"issue":"9","key":"10.7717\/peerj.13445\/ref-12","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.1111\/ggi.12590","article-title":"Prevalence of sarcopenia in acute hip fracture patients and its influence on short-term clinical outcome","volume":"16","author":"Gonz\u00e1lez-Montalvo","year":"2016","journal-title":"Geriatrics & Gerontology International"},{"issue":"4","key":"10.7717\/peerj.13445\/ref-13","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1017\/S0029665115000129","article-title":"Skeletal muscle mass and quality: evolution of modern measurement concepts in the context of sarcopenia","volume":"74","author":"Heymsfield","year":"2015","journal-title":"The Proceedings of the Nutrition Society"},{"issue":"Suppl 86","key":"10.7717\/peerj.13445\/ref-14","doi-asserted-by":"publisher","first-page":"e9890","DOI":"10.7717\/peerj.9890","article-title":"A prediction modeling based on SNOT-22 score for endoscopic nasal septoplasty: a retrospective study","volume":"8","author":"Kang","year":"2020","journal-title":"PeerJ"},{"issue":"4","key":"10.7717\/peerj.13445\/ref-15","doi-asserted-by":"publisher","first-page":"227","DOI":"10.11005\/jbm.2018.25.4.227","article-title":"Effect of sarcopenia on postoperative mortality in osteoporotic hip fracture patients","volume":"25","author":"Kim","year":"2018","journal-title":"Journal of Bone Metabolism"},{"issue":"5","key":"10.7717\/peerj.13445\/ref-16","doi-asserted-by":"publisher","first-page":"1569","DOI":"10.1007\/s00198-017-3929-z","article-title":"The association between sarcopenia and functional outcomes among older patients with hip fracture undergoing in-hospital rehabilitation","volume":"28","author":"Landi","year":"2017","journal-title":"Osteoporosis International"},{"issue":"3 Part 1","key":"10.7717\/peerj.13445\/ref-17","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1093\/geront\/9.3_Part_1.179","article-title":"Assessment of older people: self-maintaining and instrumental activities of daily living","volume":"9","author":"Lawton","year":"1969","journal-title":"The Gerontologist"},{"issue":"11","key":"10.7717\/peerj.13445\/ref-18","doi-asserted-by":"publisher","first-page":"1162","DOI":"10.1200\/JCO.2016.67.5140","article-title":"Impact of examined lymph node count on precise staging and long-term survival of resected non\u2013small-cell lung cancer: a population study of the us seer database and a chinese multi-institutional registry","volume":"35","author":"Liang","year":"2017","journal-title":"Journal of Clinical Oncology"},{"issue":"11","key":"10.7717\/peerj.13445\/ref-19","doi-asserted-by":"publisher","first-page":"2407","DOI":"10.1016\/j.injury.2020.08.027","article-title":"Prognosis of nonoperative treatment in elderly patients with a hip fracture: a systematic review and meta-analysis","volume":"51","author":"Loggers","year":"2020","journal-title":"Injury"},{"issue":"9","key":"10.7717\/peerj.13445\/ref-20","doi-asserted-by":"publisher","first-page":"1154","DOI":"10.1016\/j.acra.2017.02.008","article-title":"Diagnosing sarcopenia on thoracic computed tomography: quantitative assessment of skeletal muscle mass in patients undergoing transcatheter aortic valve replacement","volume":"24","author":"Nemec","year":"2017","journal-title":"Academic Radiology"},{"key":"10.7717\/peerj.13445\/ref-21","doi-asserted-by":"publisher","first-page":"1347","DOI":"10.2147\/PPA","article-title":"Health-related quality of life in elderly diabetic outpatients in Vietnam","volume":"12","author":"Nguyen","year":"2018","journal-title":"Patient Preference and Adherence"},{"issue":"3","key":"10.7717\/peerj.13445\/ref-22","doi-asserted-by":"publisher","first-page":"305","DOI":"10.3390\/ijerph16030305","article-title":"Health-related quality of life impairment among patients with different skin diseases in Vietnam: a cross-sectional study","volume":"16","author":"Nguyen","year":"2019","journal-title":"International Journal of Environmental Research and Public Health"},{"issue":"7","key":"10.7717\/peerj.13445\/ref-23","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.1016\/j.injury.2016.04.018","article-title":"Quality of life after hip fracture in the elderly: a systematic literature review","volume":"47","author":"Peeters","year":"2016","journal-title":"Injury"},{"key":"10.7717\/peerj.13445\/ref-24","article-title":"A language and environment for statistical computing","author":"R Core Team","year":"2019"},{"issue":"5","key":"10.7717\/peerj.13445\/ref-25","doi-asserted-by":"publisher","first-page":"990S","DOI":"10.1093\/jn\/127.5.990S","article-title":"Sarcopenia: origins and clinical relevance","volume":"127","author":"Rosenberg","year":"1997","journal-title":"The Journal of Nutrition"},{"issue":"12","key":"10.7717\/peerj.13445\/ref-26","doi-asserted-by":"publisher","first-page":"2888","DOI":"10.3390\/ijerph15122888","article-title":"Depression and quality of life among patients living with HIV\/AIDS in the era of universal treatment access in Vietnam","volume":"15","author":"Tran","year":"2018a","journal-title":"International Journal of Environmental Research and Public Health"},{"key":"10.7717\/peerj.13445\/ref-27","doi-asserted-by":"publisher","first-page":"565153","DOI":"10.3389\/fpsyg.2020.565153","article-title":"Impact of COVID-19 on economic well-being and quality of life of the vietnamese during the national social distancing","volume":"11","author":"Tran","year":"2020","journal-title":"Frontiers in Psychology"},{"issue":"6","key":"10.7717\/peerj.13445\/ref-28","doi-asserted-by":"publisher","first-page":"1174","DOI":"10.3390\/ijerph15061174","article-title":"Cost-of-Illness and the health-related quality of life of patients in the dengue fever outbreak in Hanoi in 2017","volume":"15","author":"Tran","year":"2018b","journal-title":"International Journal of Environmental Research and Public Health"},{"issue":"6","key":"10.7717\/peerj.13445\/ref-29","doi-asserted-by":"publisher","first-page":"457","DOI":"10.3944\/AOTT.2009.457","article-title":"Long-term radiographic complications following treatment of unstable intertrochanteric femoral fractures with the proximal femoral nail and effects on functional results","volume":"43","author":"Uzun","year":"2009","journal-title":"Acta Orthopaedica et Traumatologica Turcica"},{"issue":"8","key":"10.7717\/peerj.13445\/ref-30","doi-asserted-by":"publisher","first-page":"1462","DOI":"10.3390\/ijerph16081462","article-title":"Health-related quality of life profiles among patients with different road traffic injuries in an urban setting of Vietnam","volume":"16","author":"Vu","year":"2019a","journal-title":"International Journal of Environmental Research and Public Health"},{"issue":"19","key":"10.7717\/peerj.13445\/ref-31","doi-asserted-by":"publisher","first-page":"3623","DOI":"10.3390\/ijerph16193623","article-title":"Effects of chronic comorbidities on the health-related quality of life among older patients after falls in vietnamese hospitals","volume":"16","author":"Vu","year":"2019b","journal-title":"International Journal of Environmental Research and Public Health"},{"issue":"1","key":"10.7717\/peerj.13445\/ref-32","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1186\/s12877-016-0386-z","article-title":"Estimation of prevalence of sarcopenia by using a new bioelectrical impedance analysis in Chinese community-dwelling elderly people","volume":"16","author":"Wang","year":"2016","journal-title":"BMC Geriatrics"},{"issue":"4","key":"10.7717\/peerj.13445\/ref-33","doi-asserted-by":"publisher","first-page":"3312","DOI":"10.18632\/aging.102814","article-title":"Analysis of immune-related signatures of lung adenocarcinoma identified two distinct subtypes: implications for immune checkpoint blockade therapy","volume":"12","author":"Wang","year":"2020","journal-title":"Sedentary Life and Nutrition"},{"issue":"3","key":"10.7717\/peerj.13445\/ref-34","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1302\/0301-620X.87B3.15300","article-title":"The effect of hospital type and surgical delay on mortality after surgery for hip fracture","volume":"87","author":"Weller","year":"2005","journal-title":"The Journal of Bone and Joint Surgery. British Volume"},{"key":"10.7717\/peerj.13445\/ref-35","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2021\/6620504","article-title":"A prediction modeling based on the hospital for special surgery (HSS) knee score for poor postoperative functional prognosis of elderly patients with patellar fractures","volume":"2021","author":"Ying","year":"2021","journal-title":"BioMed Research International"},{"issue":"4","key":"10.7717\/peerj.13445\/ref-36","doi-asserted-by":"publisher","first-page":"e27","DOI":"10.3346\/jkms.2018.33.e27","article-title":"Osteosarcopenia in patients with hip fracture is related with high mortality","volume":"33","author":"Yoo","year":"2018","journal-title":"Journal of Korean Medical Science"},{"key":"10.7717\/peerj.13445\/ref-37","doi-asserted-by":"publisher","first-page":"6666453","DOI":"10.1155\/2021\/6666453","article-title":"A prediction model for cognitive impairment risk in colorectal cancer after chemotherapy treatment","volume":"2021","author":"Zhou","year":"2021","journal-title":"BioMed Research International"}],"container-title":["PeerJ"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/peerj.com\/articles\/13445.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/peerj.com\/articles\/13445.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/peerj.com\/articles\/13445.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/peerj.com\/articles\/13445.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T08:58:50Z","timestamp":1655283530000},"score":1,"resource":{"primary":{"URL":"https:\/\/peerj.com\/articles\/13445"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,15]]},"references-count":37,"alternative-id":["10.7717\/peerj.13445"],"URL":"https:\/\/doi.org\/10.7717\/peerj.13445","archive":["CLOCKSS","LOCKSS","Portico"],"relation":{},"ISSN":["2167-8359"],"issn-type":[{"value":"2167-8359","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,15]]},"article-number":"e13445"}}