{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T16:52:00Z","timestamp":1783529520042,"version":"3.55.0"},"reference-count":34,"publisher":"PeerJ","license":[{"start":{"date-parts":[[2022,11,30]],"date-time":"2022-11-30T00:00:00Z","timestamp":1669766400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:sec>\n<jats:title>Background<\/jats:title>\n<jats:p>Intussusception can occur at any age and is common in children but less common in adults. This study aimed to evaluate our experience of 51 adult intussusception and study the etiology, clinical manifestations, diagnosis, and treatment.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>This analysis assessed the clinical manifestations, etiology, diagnosis, and treatment of adult intussusception in 51 adult patients at the Department of Gastrointestinal Surgery of China-Japan Union Hospital of Jilin University from January 2010 to December 2020.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>The mean age of the cohort was 54.43 \u00b1 18.21 years, and 42 patients were diagnosed by abdominal ultrasonography and abdominal computed tomography (CT). Among them, 76.5% (39\/51) had abdominal pain, 11.8% (6\/51) had blood in stool, and 5.9% (3\/51) had a palpable abdominal mass. Of these, 62.7% had tumors: malignant accounted for 39.2% (20\/51) and benign accounted for 23.5% (12\/51). CT is the preferred imaging method with a sensitivity of 92.2%, while colonoscopy provides a complementary diagnosis in patients involving the colon. All patients underwent surgical treatment, including 21.6% (11\/51) laparoscopic surgery, 74.5% (38\/51) open surgery, and 5.9% (3\/51) intussusception reduction during the operation. The average operation time of the open group was 133.27 \u00b1 43.75 min and the average hospital stay was 16.24 \u00b1 12.55 days, while the average operation time of the laparoscopic group was 140.50 \u00b1 46.15 mins, and the average hospital stay was 16.60 \u00b1 16.98 days (<jats:italic>P<\/jats:italic> &gt; 0.05).<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Conclusion<\/jats:title>\n<jats:p>Adult intussusception is a rare disease in clinic. Laparoscopic surgery can be useful and safe for adult intussusception.<\/jats:p>\n<\/jats:sec>","DOI":"10.7717\/peerj.14495","type":"journal-article","created":{"date-parts":[[2022,11,30]],"date-time":"2022-11-30T09:55:58Z","timestamp":1669802158000},"page":"e14495","source":"Crossref","is-referenced-by-count":15,"title":["Adult intussusception: a challenge to laparoscopic surgery?"],"prefix":"10.7717","volume":"10","author":[{"given":"Mingze","family":"Sun","sequence":"first","affiliation":[{"name":"Department of General Surgery, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongmin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Colorectal and Anal Surgery, China-Japan Union Hospital of Jilin University, Changchun, Jilin, 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