{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,1,5]],"date-time":"2023-01-05T07:08:22Z","timestamp":1672902502093},"reference-count":23,"publisher":"PeerJ","license":[{"start":{"date-parts":[[2023,1,4]],"date-time":"2023-01-04T00:00:00Z","timestamp":1672790400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Project of Hebei Medical Science Research Plan in 2021","award":["20210893"],"award-info":[{"award-number":["20210893"]}]},{"name":"Scientific Research Project for Higher Education in Hebei Province","award":["Z2020129"],"award-info":[{"award-number":["Z2020129"]}]},{"name":"Basic Research Foundation of Hebei North University","award":["QN2020027"],"award-info":[{"award-number":["QN2020027"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"\n Objective<\/jats:title>\n The effect of fetal oval foramen restriction and premature contraction of the arterial catheter for the right heart function of fetuses and infants was studied by evaluating the right and left ventricular (RV\/LV) ratios, the tricuspid annular plane systolic excursion (TAPSE) value, and the Tei index of right heart function parameters.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n This study was approved by the Ethics Committee of First Affiliated Hospital of Hebei North University (K20190116). We collected 257 fetuses between March 2020 and December 2021. Among these, 98 fetuses that did not have any heart abnormalities were assigned to group A, 91 fetuses with restriction of the left and right atrial channels were assigned to group B, and 68 fetuses with premature contraction of the arterial catheter were assigned to group C. The ventricular transverse diameter, the right heart TAPSE value and the Tei index of fetuses in late pregnancy and 90 days after birth were measured in the three groups, and the diagnostic value of each index for the right heart function injury was evaluated. P<\/jats:italic>\u00a0<\u00a00.05 indicates significant.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n The P-value of the TAPSE value and Tei index of infants in BC and AC groups and postnatal infants were less than 0.05, which was significant. In the BC group, the RV\/LV ratio of fetuses was compared when P<\/jats:italic>\u00a0>\u00a00.05, which was not significant; however, P<\/jats:italic>\u00a0<\u00a00.05 after birth was considered significant. For fetuses and postnatal infants in the BC group, the RV\/LV ratio was negatively associated with the TAPSE value. However, it was positively associated with the Tei index; Diagnostic test results. To predict impaired right heart function after birth, TAPSE had low diagnostic value, RV\/LV and Tei index had high diagnostic value.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Oval foramen restriction and premature contraction of the arterial catheter may affect the right heart function after birth and be related to the degree of the right heart enlargement. Although TAPSE prediction of the fetal and postnatal right heart function is limited, the RV\/LV ratio and the Tei index can be used to predict impaired right heart function after birth.<\/jats:p>\n <\/jats:sec>","DOI":"10.7717\/peerj.14702","type":"journal-article","created":{"date-parts":[[2023,1,4]],"date-time":"2023-01-04T08:24:16Z","timestamp":1672820656000},"page":"e14702","source":"Crossref","is-referenced-by-count":0,"title":["Effect of oval foramen restriction and premature contraction of the arterial catheter on right heart function of fetuses and infants"],"prefix":"10.7717","volume":"11","author":[{"given":"Hongqiang","family":"Liu","sequence":"first","affiliation":[{"name":"The First Affiliated Hospital of Hebei North University, Zhangjiakou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinqiu","family":"Li","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Hebei North University, Zhangjiakou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaolong","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Aerospace Medicine, Fourth Military Medical University, Xi\u2019an, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yicheng","family":"Wang","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Hebei North University, Zhangjiakou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dehui","family":"Wen","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Hebei North University, Zhangjiakou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fengqun","family":"Dong","sequence":"additional","affiliation":[{"name":"Hebei Maternity Hospital, Shijiazhuang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Wang","sequence":"additional","affiliation":[{"name":"Life Science Research 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