{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:59:47Z","timestamp":1787032787208,"version":"build-2736575974"},"reference-count":68,"publisher":"PeerJ","license":[{"start":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T00:00:00Z","timestamp":1683763200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005668","name":"Funda\u00e7\u00e3o de Apoio \u00e0 Pesquisa do Distrito Federal","doi-asserted-by":"crossref","award":["193.000.947\/2015"],"award-info":[{"award-number":["193.000.947\/2015"]}],"id":[{"id":"10.13039\/501100005668","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100005668","name":"Funda\u00e7\u00e3o de Apoio \u00e0 Pesquisa do Distrito Federal","doi-asserted-by":"crossref","award":["193.00000219\/2019-71"],"award-info":[{"award-number":["193.00000219\/2019-71"]}],"id":[{"id":"10.13039\/501100005668","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico CNPq, Brazil","award":["478648\/2013-8"],"award-info":[{"award-number":["478648\/2013-8"]}]},{"name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico CNPq, Brazil","award":["421384\/2018-2"],"award-info":[{"award-number":["421384\/2018-2"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>\n                    Preparation for oxidative stress (POS) is a widespread adaptive response to harsh environmental conditions, whose hallmark is the upregulation of antioxidants. In contrast to controlled laboratory settings, animals are exposed to multiple abiotic stressors under natural field conditions. Still, the interplay between different environmental factors in modulating redox metabolism in natural settings remains largely unexplored. Here, we aim to shed light on this topic by assessing changes in redox metabolism in the mussel\n                    <jats:italic>Brachidontes solisianus<\/jats:italic>\n                    naturally exposed to a tidal cycle. We compared the redox biochemical response of mussels under six different natural conditions in the field along two consecutive days. These conditions differ in terms of chronology, immersion\/emersion, and solar radiation, but not in terms of temperature. Animals were collected after being exposed to air early morning (7:30), immersed during late morning and afternoon (8:45\u201315:30), and then exposed to air again late afternoon towards evening (17:45\u201321:25), in two days. Whole body homogenates were used to measure the activity of antioxidant (catalase, glutathione transferase and glutathione reductase) and metabolic (glucose 6-phosphate dehydrogenase, malate dehydrogenase, isocitrate dehydrogenase and pyruvate kinase) enzymes, reduced (GSH) and disulfide (GSSG) glutathione levels, and oxidative stress markers (protein carbonyl and thiobarbituric acid reactive substances). Air and water temperature remained stable between 22.5\u00a0\u00b0C and 26\u00a0\u00b0C during both days. Global solar radiation (GSR) greatly differed between days, with a cumulative GSR of 15,381 kJ\/m\n                    <jats:sup>2<\/jats:sup>\n                    for day 1 and 5,489 kJ\/m\n                    <jats:sup>2<\/jats:sup>\n                    for day 2, whose peaks were 2,240 kJ\/m\n                    <jats:sup>2<\/jats:sup>\n                    \/h at 14:00 on day 1 and 952 kJ\/m\n                    <jats:sup>2<\/jats:sup>\n                    \/h at 12:00 on day 2. Compared with animals underwater, emersion during early morning did not elicit any alteration in redox biomarkers in both days. Air exposure for 4 h in the late afternoon towards evening caused oxidative damage to proteins and lipids and elicited GSH synthesis in animals that had been previously exposed to high GSR during the day. In the following day, when GSR was much lower, exposure to air under the same conditions (duration, time, and temperature) had no effect on any redox biomarker. These findings suggest that air exposure under low-intensity solar radiation is not sufficient to trigger POS in\n                    <jats:italic>B. solisianus<\/jats:italic>\n                    in its natural habitat. Thus, natural UV radiation is possibly a key environmental factor that combined to air exposure induces the POS-response to the stressful event of tidal variation in this coastal species.\n                  <\/jats:p>","DOI":"10.7717\/peerj.15345","type":"journal-article","created":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T03:55:34Z","timestamp":1683777334000},"page":"e15345","source":"Crossref","is-referenced-by-count":14,"title":["The role of solar radiation and tidal emersion on oxidative stress and glutathione synthesis in mussels exposed to air"],"prefix":"10.7717","volume":"11","author":[{"given":"Daniel C.","family":"Moreira","sequence":"first","affiliation":[{"name":"Department of Cell Biology, University of Brasilia, Brasilia, Brazil"},{"name":"Faculty of Medicine, University of Brasilia, Brasilia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"Aur\u00e9lio da Costa Tavares Sabino","sequence":"additional","affiliation":[{"name":"Department of Cell Biology, University of Brasilia, Brasilia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Minari","sequence":"additional","affiliation":[{"name":"Department of Cell Biology, University of Brasilia, Brasilia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe","family":"Torres Brasil Kuzniewski","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Brasilia, Brasilia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronaldo","family":"Angelini","sequence":"additional","affiliation":[{"name":"Department of Civil and Environmental Engineering, Federal University of Rio Grande do Norte, Natal, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo","family":"Hermes-Lima","sequence":"additional","affiliation":[{"name":"Department of Cell Biology, University of Brasilia, 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