{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T02:56:36Z","timestamp":1768618596965,"version":"3.49.0"},"reference-count":55,"publisher":"PeerJ","license":[{"start":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T00:00:00Z","timestamp":1716508800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"The Engineering & Physical Sciences Research Council, Swemac","award":["2439558"],"award-info":[{"award-number":["2439558"]}]},{"name":"The University of Liverpool and Medical Research Council (MRC) and Versus Arthritis as part of the MRC Versus Arthritis Centre for Integrated Research into Musculoskeletal Ageing","award":["MR\/P020941\/1"],"award-info":[{"award-number":["MR\/P020941\/1"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Surgical intervention is a common option for the treatment of wrist joint arthritis and traumatic wrist injury. Whether this surgery is arthrodesis or a motion preserving procedure such as arthroplasty, wrist joint biomechanics are inevitably altered. To evaluate effects of surgery on parameters such as range of motion, efficiency and carpal kinematics, repeatable and controlled motion of cadaveric specimens is required. This study describes the development of a device that enables cadaveric wrist motion to be simulated before and after motion preserving surgery in a highly controlled manner. The simulator achieves joint motion through the application of predetermined displacements to the five major tendons of the wrist, and records tendon forces. A pilot experiment using six wrists aimed to evaluate its accuracy and reproducibility. Biplanar X-ray videoradiography (BPVR) and X-Ray Reconstruction of Moving Morphology (XROMM) were used to measure overall wrist angles before and after total wrist arthroplasty. The simulator was able to produce flexion, extension, radioulnar deviation, dart thrower\u2019s motion and circumduction within previously reported functional ranges of motion. Pre- and post-surgical wrist angles did not significantly differ. Intra-specimen motion trials were repeatable; root mean square errors between individual trials and average wrist angle and tendon force profiles were below 1\u00b0 and 2 N respectively. Inter-specimen variation was higher, likely due to anatomical variation and lack of wrist position feedback. In conclusion, combining repeatable intra-specimen cadaveric motion simulation with BPVR and XROMM can be used to determine potential effects of motion preserving surgeries on wrist range of motion and biomechanics.<\/jats:p>","DOI":"10.7717\/peerj.17179","type":"journal-article","created":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T07:58:40Z","timestamp":1716537520000},"page":"e17179","source":"Crossref","is-referenced-by-count":2,"title":["Evaluation of a cadaveric wrist motion simulator using marker-based X-ray reconstruction of moving morphology"],"prefix":"10.7717","volume":"12","author":[{"given":"Joanna","family":"Glanville","sequence":"first","affiliation":[{"name":"School of Engineering, University of Liverpool, Liverpool, Merseyside, United Kingdom"},{"name":"Department of Musculoskeletal & Ageing Science, University of Liverpool, Liverpool, Merseyside,  United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl 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