{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T06:00:05Z","timestamp":1792044005143,"version":"4.4.0"},"reference-count":33,"publisher":"PeerJ","license":[{"start":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T00:00:00Z","timestamp":1719532800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"The FPTA Linda Craft award"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:sec>\n               <jats:title>Introduction<\/jats:title>\n               <jats:p>High velocity thrust manipulation is commonly used when managing joint dysfunctions. Often, these thrust maneuvers will elicit an audible pop. It has been unclear what conclusively causes this audible sound and its clinical meaningfulness. This study sought to identify the effect of the audible pop on brainwave activity directly following a prone T7 thrust manipulation in asymptomatic\/healthy subjects.<\/jats:p>\n            <\/jats:sec>\n            <jats:sec>\n               <jats:title>Methods<\/jats:title>\n               <jats:p>This was a quasi-experimental repeated measure study design in which 57 subjects completed the study protocol. Brain wave activity was measured with the Emotiv EPOC+, which collects data with a frequency of 128 HZ and has 14 electrodes. Testing was performed in a controlled environment with minimal electrical interference (as measured with a Gauss meter), temperature variance, lighting variance, sound pollution, and other variable changes that could have influenced or interfered with pure EEG data acquisition. After accommodation each subject underwent a prone T7 posterior-anterior thrust manipulation. Immediately after the thrust manipulation the brainwave activity was measured for 10 seconds.<\/jats:p>\n            <\/jats:sec>\n            <jats:sec>\n               <jats:title>Results<\/jats:title>\n               <jats:p>The non-audible group (<jats:italic>N<\/jats:italic>\u00a0=\u00a020) consisted of 55% males, and the audible group (<jats:italic>N<\/jats:italic>\u00a0=\u00a037) consisted of 43% males. The non-audible group EEG data revealed a significant change in brain wave activity under some of the electrodes in the frontal, parietal, and the occipital lobes. In the audible group, there was a significant change in brain wave activity under all electrodes in the frontal lobes, the parietal lobe, and the occipital lobes but not the temporal lobes.<\/jats:p>\n            <\/jats:sec>\n            <jats:sec>\n               <jats:title>Conclusion<\/jats:title>\n               <jats:p>The audible sounds caused by a thoracic high velocity thrust manipulation did not affect the activity in the audible centers in the temporal brain region. The results support the hypothesis that thrust manipulation with or without audible sound results in a generalized relaxation immediately following the manipulation. The absence of a significant difference in brainwave activity in the frontal lobe in this study might indicate that the audible pop does not produce a \u201cplacebo\u201d mechanism.<\/jats:p>\n            <\/jats:sec>","DOI":"10.7717\/peerj.17622","type":"journal-article","created":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T07:18:15Z","timestamp":1719559095000},"page":"e17622","source":"Crossref","is-referenced-by-count":7,"title":["The effect of a spinal thrust manipulation\u2019s audible pop on brain wave activity: a quasi-experimental repeated measure design"],"prefix":"10.7717","volume":"12","author":[{"given":"Rob","family":"Sillevis","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Sciences, Florida Gulf Coast University, Fort Myers, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Unum","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Sciences, Florida Gulf Coast University, 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