{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T13:30:01Z","timestamp":1758893401221,"version":"3.40.1"},"reference-count":24,"publisher":"PeerJ","license":[{"start":{"date-parts":[[2025,3,18]],"date-time":"2025-03-18T00:00:00Z","timestamp":1742256000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:sec>\n<jats:title>Objective<\/jats:title>\n<jats:p>To correlate the molar teeth and their periodontal conditions after orthodontic anterior removal of the molars to close the gap of missing teeth and to provide risk factor analysis and prognostic assessment for the treatment of such cases.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>Twenty-six orthodontic patients (five males and 21 females) with a total of 42 teeth were selected to undergo full-mouth orthodontic treatment due to the absence of the first\/second molar and the molar bone volume was recorded by cone-beam computed tomography (CBCT) scanning before (T0) and after (T1) the treatment, and the root volume and the bone volume of the molar teeth were calculated by three-dimensional reconstruction of the CBCT. Afterwards, the correlation analysis was performed between the molar root volume change and bone volume condition and age, gender, density, width, height of the alveolar bone in the edentulous area, edentulous gap and root condition.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>The amount of alveolar bone loss and root resorption in the anteriorly displaced molars after treatment was less than 20%. There was a statistically significant correlation between age and pre-treatment periodontal condition, distal mesial and buccal bone loss; there was a statistically significant correlation between alveolar bone width in the edentulous area and pre-treatment periodontal condition and buccal bone loss; there was a statistically significant correlation between edentulous gap and post-treatment periodontal changes and buccal bone loss; there was a statistically significant correlation between gender and lingual bone loss; and there was a statistically significant correlation between root resorption and pre-treatment There was a statistically significant correlation between the width of the alveolar bone in the edentulous area; there was no statistically significant correlation between the density and height of the alveolar bone in the edentulous area and the periodontal condition.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Conclusion<\/jats:title>\n<jats:p>Closure of the missing gap by orthodontic proximal-medial movement of the molar is a feasible method, but we need to pay close attention to the width of the alveolar bone and the missing space in the edentulous area.<\/jats:p>\n<\/jats:sec>","DOI":"10.7717\/peerj.18875","type":"journal-article","created":{"date-parts":[[2025,3,18]],"date-time":"2025-03-18T08:00:44Z","timestamp":1742284844000},"page":"e18875","source":"Crossref","is-referenced-by-count":1,"title":["Factors affecting molar root and periodontal hard tissue changes after orthodontic anterior molar closure of missing tooth spaces retrospective explored based on cone-beam computed tomography three-dimensional reconstruction"],"prefix":"10.7717","volume":"13","author":[{"given":"Yuhao","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Orthodontics, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, 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Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhihui","family":"Mai","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4443","published-online":{"date-parts":[[2025,3,18]]},"reference":[{"issue":"3","key":"10.7717\/peerj.18875\/ref-1","doi-asserted-by":"publisher","first-page":"100774","DOI":"10.1016\/j.ortho.2023.100774","article-title":"Alveolar bone loss and root resorption in mesialized second molars in mandibular first molar extraction cases as compared to contralateral non-extraction side in young adults: a retrospective cross-sectional study","volume":"21","author":"Aman","year":"2023","journal-title":"International 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