{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T09:01:52Z","timestamp":1780909312071,"version":"3.54.1"},"reference-count":21,"publisher":"PeerJ","license":[{"start":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T00:00:00Z","timestamp":1780876800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Central Guiding Funds for Local Science and Technology Development","award":["GuikeZY24212064"],"award-info":[{"award-number":["GuikeZY24212064"]}]},{"DOI":"10.13039\/501100017691","name":"Guangxi Key Research and Development Program","doi-asserted-by":"crossref","award":["Guike AB23075149"],"award-info":[{"award-number":["Guike AB23075149"]}],"id":[{"id":"10.13039\/501100017691","id-type":"DOI","asserted-by":"crossref"}]},{"name":"The Young Scientists project of Guangxi Hospital Division of The First Affiliated Hospital, Sun Yat-sen University","award":["YQ2024023"],"award-info":[{"award-number":["YQ2024023"]}]},{"name":"The Research Funds of Guangxi Zhuang Autonomous Region Health Commission","award":["NO: Z202000666"],"award-info":[{"award-number":["NO: Z202000666"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>This study was designed to validate the formula of New Baseline Glomerular Filtration Rate (NB-GFR) within a multicenter cohort of southern Chinese patients who underwent radical nephrectomy (RN) or partial nephrectomy (PN), with a specific focus on assessing its accuracy and effectiveness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The predictive capability of the formula proposed by professor Palacios DA for estimating NB-GFR after PN or RN was evaluated, with a focus on its efficacy in the southern Chinese population. A retrospective analysis was conducted involving 398 RN patients and 185 PN patients from three hospitals between 2015 and 2022. The correlation between the postoperative NB-GFR predicted by the equation and the actual GFR of the patients was analyzed, and the level of agreement was assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We found strong positive correlation between NB-GFR and GFR after PN, with a correlation coefficient of R = 0.645, 95% confidence interval (95% confidence interval (CI)) [0.552\u20130.722],\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.001. Moderate positive correlation was observed between NB-GFR and GFR after RN, with R = 0.434, 95% CI [0.339\u20130.501]. Lin\u2019s concordance correlation coefficient (CCC) analysis demonstrated a moderate concordance between post-operative GFR and NB-GFR, with a CCC value of 0.522 (95% CI [0.461\u20130.579],\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.001) for RN and 0.533 (95% CI [0.472\u20130.589],\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.001) for PN.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The NB-GFR prediction equation demonstrates moderate concordance with actual postoperative GFR in southern Chinese patients undergoing RN or PN, indicating broad application potential.<\/jats:p>\n                  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