{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T08:59:15Z","timestamp":1790326755390,"version":"4.1.0"},"reference-count":20,"publisher":"PeerJ","license":[{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>\n                    This study aimed to evaluate the prevalence of sexual dysfunction among women diagnosed with gestational trophoblastic disease (GTD) who were undergoing outpatient follow-up at a university hospital. A cross-sectional study was conducted involving 73 women aged \u2265 18 yr. Data were collected using a structured questionnaire addressing sociodemographic and clinical characteristics, in addition to the Sexual Quotient - Female Version (SQ-F) to assess sexual function. Most participants were aged 18\u201330 yr (58.9%), married (74.0%), and reported using oral contraceptives (52.1%). Based on the total SQ-F score, 63.0% (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a046) of participantsdemonstrated adequate sexual satisfaction. However, 15.0% reported experiencing dyspareunia, and 45.2% reported difficulty maintaining concentration during sexual activity. Sexual dysfunction was significantly associated with smoking (Prevalence ratios (PR) = 2.88;\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.015) and residence in rural areas (PR = 3.47;\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.003). Although the overall prevalence of sexual dysfunction was not higher than national estimates, the findings identify specific vulnerabilities that may adversely affect sexual health. These factors should be considered in the comprehensive clinical management of women with GTD.\n                  <\/jats:p>","DOI":"10.7717\/peerj.21427","type":"journal-article","created":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T08:00:21Z","timestamp":1790323221000},"page":"e21427","source":"Crossref","is-referenced-by-count":0,"title":["Sexual dysfunction in women with gestational trophoblastic disease: a cross-sectional study in Recife, Pernambuco, Brazil"],"prefix":"10.7717","volume":"14","author":[{"given":"Edinaldo Brito dos","family":"Santos","sequence":"first","affiliation":[{"name":"Centro Universit\u00e1rio FMABC, Santo Andr\u00e9, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elias Ferreira de","family":"Melo Jr","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josielle Carvalho de","family":"Lima","sequence":"additional","affiliation":[{"name":"Faculdade Est\u00e1cio do Recife, Recife, Pernambuco, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Auro Del","family":"Giglio","sequence":"additional","affiliation":[{"name":"Centro Universit\u00e1rio FMABC, Santo Andr\u00e9, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4443","published-online":{"date-parts":[[2026,9,25]]},"reference":[{"issue":"2","key":"10.7717\/peerj.21427\/ref-1","first-page":"89","article-title":"Quociente sexual feminino: um question\u00e1rio brasileiro para avaliar a atividade sexual da mulher","volume":"14","author":"Abdo","year":"2009","journal-title":"Diagn\u00f3stico e Tratamento"},{"key":"10.7717\/peerj.21427\/ref-2","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1038\/sj.ijir.3901198","article-title":"Prevalence of sexual dysfunctions and correlated conditions in a sample of Brazilian women: results from the Brazilian Study on Sexual Behavior (BSSB)","volume":"16","author":"Abdo","year":"2004","journal-title":"International Journal of Impotence Research"},{"key":"10.7717\/peerj.21427\/ref-3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12905-020-00925-0","article-title":"Psychological consequences and quality of life in women with endometriosis","volume":"20","author":"Abr\u00e3o","year":"2020","journal-title":"BMC Women\u2019s Health"},{"issue":"3","key":"10.7717\/peerj.21427\/ref-4","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1111\/1471-0528.16880","article-title":"The psychological impact of gestational trophoblastic disease: a prospective observational multicentre cohort study","volume":"129","author":"Blok","year":"2022","journal-title":"BJOG: An International Journal of Obstetrics & Gynaecology"},{"key":"10.7717\/peerj.21427\/ref-5","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1002\/ijgo.13791","article-title":"Diagnosis and management of gestational trophoblastic disease: 2021 update","volume":"152","author":"Braga","year":"2021","journal-title":"International Journal of Gynaecology and Obstetrics"},{"key":"10.7717\/peerj.21427\/ref-6","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1089\/jwh.2015.5703","article-title":"The impact of oral contraceptive use on sexual function in women of reproductive age","volume":"51","author":"Caliman","year":"2023","journal-title":"Femina"},{"key":"10.7717\/peerj.21427\/ref-7","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.bpobgyn.2020.10.007","article-title":"Psychological aspects and fertility issues of GTD. 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