{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T09:09:15Z","timestamp":1772269755786,"version":"3.50.1"},"reference-count":16,"publisher":"PeerJ","license":[{"start":{"date-parts":[[2018,7,16]],"date-time":"2018-07-16T00:00:00Z","timestamp":1531699200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The use of an implantable cardioverter-defibrillator (ICD) has been established as an effective secondary prevention strategy for ventricular tachycardia (VT)\/ventricular fibrillation (VF). However, few reports discuss the difference in clinical predictors for recurrent VT\/VF between patients with ischemic cardiomyopathy (ICM) and patients with dilated cardiomyopathy (DCM).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      From May 2004 to December 2015, 132 consecutive patients who had ICM (\n                      <jats:italic>n<\/jats:italic>\n                      = 94) or DCM (\n                      <jats:italic>n<\/jats:italic>\n                      = 38) and had received ICD implantation for secondary prevention were enrolled in this study. All anti-tachycardia events during follow-up were validated. The clinical characteristics and echocardiographic parameters were obtained for comparison. The incidence of recurrence of VT\/VF, cardiovascular mortality, all-cause mortality, the change of left ventricular ejection fraction (LVEF) and LV volume were analyzed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At a mean follow-up of 3.62 \u00b1 2.93 years, 34 patients (36.2%) in the ICM group and 22 patients (57.9%) in the DCM group had a recurrence of VT\/VF episodes (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.032). The DCM group had a lower LVEF (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.019), a larger LV end-diastolic volume (LVEDV) (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.001), a higher prevalence of LVEDV &gt;158 mL (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.010), and a larger LV end-systolic volume (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.010) than the ICM group. LVEDV &gt;158 mL and no use of angiotensin-converting-enzyme inhibitor\/angiotensin receptor blocker were independent predictors of recurrences of VT\/VF in ICM patients but not in DCM patients. There were no difference in cardiovascular mortality and all-cause mortality between the ICM and DCM patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The DCM patients had a higher recurrence rate of VT\/VF than did the ICM patients during long-term follow-up. An enlarged LV is an independent predictor of the recurrence of VT\/VF in ICM patients receiving ICD for secondary prevention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.7717\/peerj.5312","type":"journal-article","created":{"date-parts":[[2018,7,16]],"date-time":"2018-07-16T04:11:30Z","timestamp":1531714290000},"page":"e5312","source":"Crossref","is-referenced-by-count":6,"title":["Comparison of ventricular tachyarrhythmia recurrence between ischemic cardiomyopathy and dilated cardiomyopathy: a retrospective study"],"prefix":"10.7717","volume":"6","author":[{"given":"Chih-Yuan","family":"Fang","sequence":"first","affiliation":[{"name":"Cardiology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan"},{"name":"Chang Gung University College of Medicine, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huang-Chung","family":"Chen","sequence":"additional","affiliation":[{"name":"Cardiology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan"},{"name":"Chang Gung University College of Medicine, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yung-Lung","family":"Chen","sequence":"additional","affiliation":[{"name":"Cardiology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan"},{"name":"Chang Gung University College of Medicine, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tzu-Hsien","family":"Tsai","sequence":"additional","affiliation":[{"name":"Cardiology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan"},{"name":"Chang Gung University College of Medicine, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kuo-Li","family":"Pan","sequence":"additional","affiliation":[{"name":"Chang Gung University College of Medicine, Taiwan"},{"name":"Cardiology, Chang Gung Memorial Hospital, Chiayi, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Sheng","family":"Lin","sequence":"additional","affiliation":[{"name":"Chang Gung University College of Medicine, Taiwan"},{"name":"Cardiology, Chang Gung Memorial Hospital, Chiayi, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mien-Cheng","family":"Chen","sequence":"additional","affiliation":[{"name":"Cardiology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan"},{"name":"Chang Gung University College of Medicine, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei-Chieh","family":"Lee","sequence":"additional","affiliation":[{"name":"Cardiology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan"},{"name":"Chang Gung University College of Medicine, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4443","published-online":{"date-parts":[[2018,7,16]]},"reference":[{"issue":"2","key":"10.7717\/peerj.5312\/ref-1","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1007\/s10840-005-4547-9","article-title":"Sudden cardiac death unresponsive to implantable defibrillator therapy: an urgent target for clinicians industry and government","volume":"14","author":"Anderson","year":"2005","journal-title":"Journal of Interventional Cardiac Electrophysiology"},{"issue":"3","key":"10.7717\/peerj.5312\/ref-2","doi-asserted-by":"publisher","first-page":"e005515","DOI":"10.1161\/jaha.117.005515","article-title":"Implantable cardioverter-defibrillators for secondary prevention of sudden cardiac death: a review","volume":"6","author":"Borne","year":"2017","journal-title":"Journal of the American Heart Association"},{"issue":"1","key":"10.7717\/peerj.5312\/ref-3","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1161\/01.cir.61.1.137","article-title":"Accuracy and reproducibility of new M-mode echocardiographic recommendations for measuring left ventricular dimensions","volume":"61","author":"Crawford","year":"1980","journal-title":"Circulation"},{"issue":"12","key":"10.7717\/peerj.5312\/ref-4","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.amjcard.2005.09.060","article-title":"Drugs for left ventricular remodeling in heart failure","volume":"96","author":"Frigerio","year":"2005","journal-title":"American Journal of Cardiology"},{"issue":"5","key":"10.7717\/peerj.5312\/ref-5","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1536\/ihj.47.763","article-title":"Appropriate ICD therapy in patients with idiopathic dilated cardiomyopathy: long term follow-up","volume":"47","author":"Karaoguz","year":"2006","journal-title":"International Heart Journal"},{"issue":"1","key":"10.7717\/peerj.5312\/ref-6","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.jacep.2016.06.001","article-title":"Survival after secondary prevention implantable cardioverter-defibrillator placement","volume":"3","author":"Katz","year":"2017","journal-title":"JACC: Clinical Electrophysiology"},{"issue":"8","key":"10.7717\/peerj.5312\/ref-7","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1093\/europace\/eul082","article-title":"Predictors of VT\/VF occurrence in ICD patients: results from the PROFIT-Study","volume":"8","author":"Klein","year":"2006","journal-title":"EP Europace"},{"key":"10.7717\/peerj.5312\/ref-8","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1016\/j.jacc.2014.04.008","article-title":"HRS\/ACC\/AHA expert consensus statement on the use of implantable cardioverter-defibrillator therapy in patients who are not included or not well represented in clinical trials","volume":"64","author":"Kusumoto","year":"2014","journal-title":"Journal of the American College of Cardiology"},{"issue":"12","key":"10.7717\/peerj.5312\/ref-9","doi-asserted-by":"publisher","first-page":"1440","DOI":"10.1016\/j.echo.2005.10.005","article-title":"Recommendations for chamber quantification: a report from the American Society of Echocardiography\u2019s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology","volume":"18","author":"Lang","year":"2005","journal-title":"Journal of the American Society of Echocardiography"},{"issue":"1","key":"10.7717\/peerj.5312\/ref-10","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1186\/s12872-016-0416-y","article-title":"Left ventricle remodeling predicts the recurrence of ventricular tachyarrhythmias in implantable cardioverter defibrillator recipients for secondary prevention","volume":"16","author":"Lee","year":"2016","journal-title":"BMC Cardiovascular Disorders"},{"issue":"6","key":"10.7717\/peerj.5312\/ref-11","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1536\/ihj.50.741","article-title":"Primary and secondary prevention of ventricular arrhythmias in dilated cardiomyopathy: nonsustained, sustained, and incessant","volume":"50","author":"Meyer","year":"2009","journal-title":"International Heart Journal"},{"issue":"10","key":"10.7717\/peerj.5312\/ref-12","doi-asserted-by":"publisher","first-page":"2419","DOI":"10.1253\/circj.cj-13-1129","article-title":"Epidemiology of arrhythmias and sudden cardiac death in Asia","volume":"77","author":"Murakoshi","year":"2013","journal-title":"Circulation Journal"},{"issue":"9","key":"10.7717\/peerj.5312\/ref-13","doi-asserted-by":"publisher","first-page":"1390","DOI":"10.1093\/oxfordjournals.eurheartj.a015074","article-title":"Mode of death in chronic heart failure: a request and proposition for more accurate classification","volume":"17","author":"Narang","year":"1996","journal-title":"European Heart Journal"},{"issue":"27","key":"10.7717\/peerj.5312\/ref-14","doi-asserted-by":"publisher","first-page":"2129","DOI":"10.1093\/eurheartj\/ehw128","article-title":"2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC","volume":"37","author":"Ponikowski","year":"2016","journal-title":"European Heart Journal"},{"key":"10.7717\/peerj.5312\/ref-15","doi-asserted-by":"crossref","first-page":"2577","DOI":"10.1161\/01.CIR.0000070420.51787.A8","article-title":"Left ventricular remodeling and ventricular arrhythmias after myocardial infarction","volume":"107","author":"St. John Sutton","year":"2003","journal-title":"Circulation"},{"issue":"10","key":"10.7717\/peerj.5312\/ref-16","doi-asserted-by":"publisher","first-page":"3294","DOI":"10.1161\/01.cir.96.10.3294","article-title":"Cardiovascular death and left ventricular remodeling two years after myocardial infarction: baseline predictors and impact of long-term use of captopril: information from the Survival and Ventricular Enlargement (SAVE) Trial","volume":"96","author":"St. John Sutton","year":"1997","journal-title":"Circulation"}],"container-title":["PeerJ"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/peerj.com\/articles\/5312.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/peerj.com\/articles\/5312.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/peerj.com\/articles\/5312.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/peerj.com\/articles\/5312.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,20]],"date-time":"2019-10-20T17:25:31Z","timestamp":1571592331000},"score":1,"resource":{"primary":{"URL":"https:\/\/peerj.com\/articles\/5312"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,16]]},"references-count":16,"alternative-id":["10.7717\/peerj.5312"],"URL":"https:\/\/doi.org\/10.7717\/peerj.5312","archive":["CLOCKSS","LOCKSS","Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.7287\/peerj.5312v0.1\/reviews\/3","asserted-by":"object"},{"id-type":"doi","id":"10.7287\/peerj.5312v0.1\/reviews\/2","asserted-by":"object"},{"id-type":"doi","id":"10.7287\/peerj.5312v0.1\/reviews\/1","asserted-by":"object"},{"id-type":"doi","id":"10.7287\/peerj.5312v0.2\/reviews\/1","asserted-by":"object"}]},"ISSN":["2167-8359"],"issn-type":[{"value":"2167-8359","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,16]]},"article-number":"e5312"}}