{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T10:52:45Z","timestamp":1790160765684,"version":"4.1.0"},"reference-count":23,"publisher":"PeerJ","license":[{"start":{"date-parts":[[2020,4,23]],"date-time":"2020-04-23T00:00:00Z","timestamp":1587600000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["AI109134"],"award-info":[{"award-number":["AI109134"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>\n                    There are increasing concerns regarding the role global climate change will have on many vector-borne diseases. Both mathematical models and laboratory experiments suggest that schistosomiasis risk may change as a result of the effects of increasing temperatures on the planorbid snails that host schistosomes. Heat pulse\/heat shock of the BS90 strain of\n                    <jats:italic>Biomphalaria glabrata<\/jats:italic>\n                    was shown to increase the rate of infection by\n                    <jats:italic>Schistosoma mansoni<\/jats:italic>\n                    , but the result was not replicable in a follow up experiment by a different lab. We characterised the susceptibility and cercarial shedding of Guadeloupean\n                    <jats:italic>B. glabrata<\/jats:italic>\n                    after infection with\n                    <jats:italic>S. mansoni<\/jats:italic>\n                    under two temperature regimes: multigenerational exposure to small increases in temperature, and extreme heat pulse events. Neither long-term, multigenerational rearing at elevated temperatures, nor transient heat pulse modified the susceptibility of Guadeloupean\n                    <jats:italic>B. glabrata<\/jats:italic>\n                    to infection (prevalence) or shedding of schistosome cercaria (intensity of infection). These findings suggest that heat pulse-induced susceptibility in snail hosts may be dependent on the strain of the snail and\/or schistosome, or on some as-yet unidentified environmental co-factor.\n                  <\/jats:p>","DOI":"10.7717\/peerj.9059","type":"journal-article","created":{"date-parts":[[2020,4,23]],"date-time":"2020-04-23T03:55:56Z","timestamp":1587614156000},"page":"e9059","source":"Crossref","is-referenced-by-count":7,"title":["Neither heat pulse, nor multigenerational exposure to a modest increase in water temperature, alters the susceptibility of Guadeloupean\n                    <i>Biomphalaria glabrata<\/i>\n                    to\n                    <i>Schistosoma mansoni<\/i>\n                    infection"],"prefix":"10.7717","volume":"8","author":[{"given":"Euan R.O.","family":"Allan","sequence":"first","affiliation":[{"name":"School of Veterinary Medicine, Pathobiology, St. George\u2019s University, St. George\u2019s, Grenada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Bollmann","sequence":"additional","affiliation":[{"name":"Integrative Biology, Oregon State University, Corvallis, OR, United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ekaterina","family":"Peremyslova","sequence":"additional","affiliation":[{"name":"Integrative Biology, Oregon State University, Corvallis, OR, United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Blouin","sequence":"additional","affiliation":[{"name":"Integrative Biology, Oregon State University, Corvallis, OR, United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4443","published-online":{"date-parts":[[2020,4,23]]},"reference":[{"key":"10.7717\/peerj.9059\/ref-1","doi-asserted-by":"publisher","first-page":"e4171","DOI":"10.7717\/peerj.4171","article-title":"The behavioral effects of antibiotic 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