{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T09:15:03Z","timestamp":1767863703745,"version":"3.49.0"},"reference-count":64,"publisher":"RCNi","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,4]]},"DOI":"10.7748\/ncyp.2024.e1492","type":"journal-article","created":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T07:50:06Z","timestamp":1704700206000},"page":"36-42","source":"Crossref","is-referenced-by-count":2,"title":["Central precocious puberty: assessment, diagnosis and decisions about treatment"],"prefix":"10.7748","volume":"36","author":[{"given":"Leah","family":"Mason","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikolaos","family":"Daskas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4499","published-online":{"date-parts":[[2024,1,8]]},"reference":[{"key":"key20240624150347_R1","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.adolescence.2018.12.007","article-title":"Physiology of puberty in boys and girls and pathological disorders affecting its onset","volume":"71","year":"2019","journal-title":"Journal of Adolescence"},{"issue":"6","key":"key20240624150347_R2","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1159\/000501336","article-title":"Use of gonadotropin-releasing hormone analogs in children: update by an international consortium","volume":"91","year":"2019","journal-title":"Hormone Research in Paediatrics"},{"issue":"4","key":"key20240624150347_R3","doi-asserted-by":"crossref","first-page":"164","DOI":"10.4274\/jcrpe.v1i4.3","article-title":"Precocious puberty and normal variant puberty: definition, etiology, diagnosis and current management","volume":"1","year":"2009","journal-title":"Journal of Clinical Research in Pediatric Endocrinology"},{"issue":"2","key":"key20240624150347_R4","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1111\/cen.14358","article-title":"Adolescent boys with constitutional delay of growth and puberty grow faster than patients with organic growth hormone deficiency","volume":"94","year":"2021","journal-title":"Clinical Endocrinology"},{"issue":"1","key":"key20240624150347_R5","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1186\/s13052-023-01506-8","article-title":"Role of luteinizing hormone urinary levels in the diagnostic and therapeutic management of female central precocious puberty","volume":"49","year":"2023","journal-title":"Italian Journal of Pediatrics"},{"key":"key20240624150347_R6","unstructured":"British Society for Paediatric Endocrinology and Diabetes (2022) Shared Care Guidelines: Use of Gonadotrophin Releasing Hormone (GnRH) Agonists \u2013 Triptorelin. www.bsped.org.uk\/media\/1978\/gnrh-agonists-shared-care-guidelines-final-version-march-2022.pdf (Last accessed: 10 November 2023.)"},{"issue":"2","key":"key20240624150347_R7","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1210\/endrev\/bnac020","article-title":"The congenital and acquired mechanisms implicated in the etiology of central precocious puberty","volume":"44","year":"2023","journal-title":"Endocrine Reviews"},{"issue":"4","key":"key20240624150347_R8","doi-asserted-by":"crossref","first-page":"e752","DOI":"10.1542\/peds.2008-1783","article-title":"Consensus statement on the use of gonadotropin-releasing hormone analogs in children","volume":"123","year":"2009","journal-title":"Pediatrics"},{"issue":"22","key":"key20240624150347_R9","doi-asserted-by":"crossref","first-page":"2366","DOI":"10.1056\/NEJMcp0800459","article-title":"Clinical practice. Precocious puberty","volume":"358","year":"2008","journal-title":"New England Journal of Medicine"},{"issue":"10","key":"key20240624150347_R10","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1176\/appi.ajp.2010.09081190","article-title":"Outcomes of early pubertal timing in young women: a prospective population-based study","volume":"167","year":"2010","journal-title":"American Journal of Psychiatry"},{"key":"key20240624150347_R11","doi-asserted-by":"crossref","first-page":"11208","DOI":"10.1038\/srep11208","article-title":"Puberty timing associated with diabetes, cardiovascular disease and also diverse health outcomes in men and women: the UK Biobank study","volume":"5","year":"2015","journal-title":"Scientific Reports"},{"issue":"3","key":"key20240624150347_R12","first-page":"213","article-title":"Accuracy of pubertal Tanner staging self-reporting","volume":"19","year":"2006","journal-title":"Journal of Pediatric Endocrinology and Metabolism"},{"key":"key20240624150347_R13","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/978-1-59745-499-5_14","volume-title":"When Puberty Is Precocious: Scientific and Clinical Aspects","year":"2007"},{"key":"key20240624150347_R14","first-page":"115","volume-title":"Practical Endocrinology and Diabetes in Children","year":"2019","edition":"4"},{"issue":"4","key":"key20240624150347_R15","first-page":"217","article-title":"Comparison of social adjustment, school satisfaction, and mental health in girls with and without precocious puberty","volume":"9","year":"2021","journal-title":"Patient Safety and Quality Improvement Journal"},{"issue":"5","key":"key20240624150347_R16","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1210\/js.2019-00036","article-title":"Treatment of central precocious puberty","volume":"3","year":"2019","journal-title":"Journal of the Endocrine Society"},{"issue":"6","key":"key20240624150347_R17","doi-asserted-by":"crossref","first-page":"2198","DOI":"10.1210\/jc.2013-1024","article-title":"Treatment and outcomes of precocious puberty: an update","volume":"98","year":"2013","journal-title":"Journal of Clinical Endocrinology & Metabolism"},{"key":"key20240624150347_R18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.12974\/2311-8687.2020.08.1","article-title":"Diagnosis of precocious puberty in girls","volume":"8","year":"2020","journal-title":"International Journal of Pediatrics and Child Health"},{"issue":"1","key":"key20240624150347_R19","doi-asserted-by":"crossref","first-page":"27","DOI":"10.17219\/acem\/31433","article-title":"The influence of GnRH analog therapy on growth in central precocious puberty","volume":"25","year":"2016","journal-title":"Advances in Clinical and Experimental Medicine"},{"issue":"8","key":"key20240624150347_R20","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/j.psyneuen.2006.05.004","article-title":"Effects of treatment with leuprolide acetate depot on working memory and executive functions in young premenopausal women","volume":"31","year":"2006","journal-title":"Psychoneuroendocrinology"},{"issue":"7","key":"key20240624150347_R21","doi-asserted-by":"crossref","first-page":"717","DOI":"10.4158\/EP-2019-0008","article-title":"Comparative efficacy and safety of three current clinical treatments for girls with central precocious puberty: a network meta-analysis","volume":"25","year":"2019","journal-title":"Endocrine Practice"},{"issue":"3","key":"key20240624150347_R22","doi-asserted-by":"crossref","first-page":"R79","DOI":"10.1530\/EJE-15-0590","article-title":"Management of endocrine disease: long-term outcomes of the treatment of central precocious puberty","volume":"174","year":"2016","journal-title":"European Journal of Endocrinology"},{"issue":"12","key":"key20240624150347_R23","doi-asserted-by":"crossref","first-page":"E2221","DOI":"10.1210\/jc.2012-2078","article-title":"Negative fetal FSH\/LH regulation in late pregnancy is associated with declined kisspeptin\/KISS1R expression in the tuberal hypothalamus","volume":"97","year":"2012","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"key20240624150347_R24","first-page":"113907","article-title":"Development of precocious puberty in children: surmised medicinal plant treatment","volume":"157","year":"2022","journal-title":"Biomedicine and Pharmacotherapy"},{"issue":"4","key":"key20240624150347_R25","doi-asserted-by":"crossref","first-page":"337","DOI":"10.32598\/jpr.9.4.960.1","article-title":"Causes of precocious puberty in children referred to an endocrine clinic in Qazvin City, Iran from 2006 to 2018","volume":"9","year":"2021","journal-title":"Journal of Pediatrics Review"},{"issue":"9","key":"key20240624150347_R26","doi-asserted-by":"crossref","first-page":"e663","DOI":"10.1210\/clinem\/dgad202","article-title":"The association of accelerated early growth, timing of puberty, and metabolic consequences in children","volume":"108","year":"2023","journal-title":"Journal of Clinical Endocrinology & Metabolism"},{"key":"key20240624150347_R27","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1159\/000084098","article-title":"Very long-term follow-up of girls with early and late menarche","volume":"8","year":"2005","journal-title":"Endocrine Development"},{"issue":"9-10","key":"key20240624150347_R28","first-page":"573","article-title":"For premature thelarche and premature adrenarche, the case for waiting before testing","volume":"93","year":"2021","journal-title":"Hormone Research in Paediatrics"},{"issue":"1","key":"key20240624150347_R29","doi-asserted-by":"crossref","first-page":"25","DOI":"10.4306\/pi.2012.9.1.25","article-title":"Psychosocial aspects in girls with idiopathic precocious puberty","volume":"9","year":"2012","journal-title":"Psychiatry Investigations"},{"issue":"2","key":"key20240624150347_R30","doi-asserted-by":"crossref","first-page":"116","DOI":"10.6065\/apem.2019.24.2.116","article-title":"Comparing adult height gain and menarcheal age between girls with central precocious puberty treated with gonadotropin-releasing hormone agonist alone and those treated with combined growth hormone therapy","volume":"24","year":"2019","journal-title":"Annals of Pediatric Endocrinology and Metabolism"},{"issue":"2","key":"key20240624150347_R31","doi-asserted-by":"crossref","first-page":"133","DOI":"10.14740\/jocmr3710","article-title":"The gonadotropin-releasing hormone analogue therapy may not impact final height in precocious puberty of girls with onset of puberty aged 6-8 years","volume":"11","year":"2019","journal-title":"Journal of Clinical Medicine Research"},{"issue":"11","key":"key20240624150347_R32","doi-asserted-by":"crossref","first-page":"2300","DOI":"10.1111\/apa.16899","article-title":"Mini review shows that a testicular volume of 3\u2009mL was the most reliable clinical sign of pubertal onset in males","volume":"112","year":"2023","journal-title":"Acta Paediatrica"},{"issue":"Suppl1","key":"key20240624150347_R33","first-page":"723","article-title":"Pharmacokinetics and pharmacodynamics of GnRH agonists: clinical implications in pediatrics","volume":"13","year":"2000","journal-title":"Journal of Pediatric Endocrinology and Metabolism"},{"issue":"3","key":"key20240624150347_R34","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S2213-8587(15)00380-0","article-title":"Causes, diagnosis, and treatment of central precocious puberty","volume":"4","year":"2016","journal-title":"The Lancet Diabetes and Endocrinology"},{"issue":"4","key":"key20240624150347_R35","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/j.ecl.2012.08.003","article-title":"Pubertal disorders and bone maturation","volume":"41","year":"2012","journal-title":"Endocrinology and Metabolism Clinics of North America"},{"issue":"1","key":"key20240624150347_R36","doi-asserted-by":"crossref","first-page":"18","DOI":"10.3109\/13561820.2010.490502","article-title":"Interprofessionalism and shared decision-making in primary care: a stepwise approach towards a new model","volume":"25","year":"2011","journal-title":"Journal of Interprofessional Care"},{"issue":"10","key":"key20240624150347_R37","doi-asserted-by":"crossref","first-page":"e0185080","DOI":"10.1371\/journal.pone.0185080","article-title":"Improved final predicted height with the injection of leuprolide in children with earlier puberty: a retrospective cohort study","volume":"12","year":"2017","journal-title":"PLoS One"},{"issue":"5","key":"key20240624150347_R38","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1111\/cen.14410","article-title":"Long-term efficacy and safety of gonadotropin-releasing hormone analog treatment in children with idiopathic central precocious puberty: a systematic review and meta-analysis","volume":"94","year":"2021","journal-title":"Clinical Endocrinology"},{"issue":"235","key":"key20240624150347_R39","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1136\/adc.44.235.291","article-title":"Variations in pattern of pubertal changes in girls","volume":"44","year":"1969","journal-title":"Archives of Diseases in Childhood"},{"issue":"10","key":"key20240624150347_R40","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1542\/pir.27.10.373","article-title":"Precocious puberty","volume":"27","year":"2006","journal-title":"Pediatrics in Review"},{"key":"key20240624150347_R41","unstructured":"Mushtaq T, Howard S\n (2023) Precocious puberty. bestpractice.bmj.com\/topics\/en-gb\/1127 (Last accessed: 10 November 2023.)"},{"key":"key20240624150347_R42","volume-title":"Physiology, Follicle Stimulating Hormone","year":"2023"},{"issue":"1","key":"key20240624150347_R43","doi-asserted-by":"crossref","first-page":"53","DOI":"10.16948\/zktipb.423576","article-title":"Precocious puberty and role of pediatric nurse","volume":"51","year":"2020","journal-title":"Zeynep Kamil T\u0131p B\u00fclteni"},{"key":"key20240624150347_R44","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/978-3-031-19443-6_2","volume-title":"Problem-Focused Reproductive Endocrinology and Infertility","year":"2023"},{"key":"key20240624150347_R45","first-page":"23","volume-title":"Pediatric Practice \u2013 Endocrinology","year":"2014","edition":"2"},{"key":"key20240624150347_R46","doi-asserted-by":"crossref","first-page":"968485","DOI":"10.3389\/fped.2022.968485","article-title":"Gonadotropin-releasing hormone analog therapies for children with central precocious puberty in the United States","volume":"10","year":"2022","journal-title":"Frontiers in Pediatrics"},{"issue":"3","key":"key20240624150347_R47","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1177\/1363460715593477","article-title":"Tanner\u2019s puberty scale: exploring the historical entanglements of children, scientific photography and sex","volume":"19","year":"2016","journal-title":"Sexualities"},{"key":"key20240624150347_R48","unstructured":"Royal College of Nursing (2019) An Integrated Career and Competency Framework for Children and Young People\u2019s Endocrine Nurse Specialists. www.rcn.org.uk\/professional-development\/publications\/pub-007-287 (Last accessed: 10 November 2023.)"},{"issue":"5","key":"key20240624150347_R49","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1159\/000479688","article-title":"One-year follow-up of girls with precocious puberty and their mothers: do psychological assessments change over time with treatment?","volume":"88","year":"2017","journal-title":"Hormone Research in Paediatrics"},{"issue":"12","key":"key20240624150347_R50","doi-asserted-by":"crossref","first-page":"e0243212","DOI":"10.1371\/journal.pone.0243212","article-title":"Long-term outcomes after gonadotropin-releasing hormone agonist treatment in boys with central precocious puberty","volume":"15","year":"2020","journal-title":"PLoS One"},{"key":"key20240624150347_R51","doi-asserted-by":"crossref","first-page":"111094","DOI":"10.1016\/j.mce.2020.111094","article-title":"Hypothalamo-pituitary axis and puberty","volume":"520","year":"2021","journal-title":"Molecular and Cellular Endocrinology"},{"issue":"11","key":"key20240624150347_R52","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.15537\/smj.2017.11.21187","article-title":"Effect of gonadotropin-releasing hormone analogue on final adult height among Jordanian children with precocious puberty","volume":"38","year":"2017","journal-title":"Saudi Medical Journal"},{"issue":"3","key":"key20240624150347_R53","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1136\/adc.51.3.170","article-title":"Clinical longitudinal standards for height, weight, height velocity, weight velocity, and stages of puberty","volume":"51","year":"1976","journal-title":"Archives of Disease in Childhood"},{"issue":"Suppl1","key":"key20240624150347_R54","first-page":"795","article-title":"Side effects of GnRH analogue treatment in childhood","volume":"13","year":"2000","journal-title":"Journal of Pediatric Endocrinology and Metabolism"},{"issue":"6","key":"key20240624150347_R55","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1515\/jpem-2021-0114","article-title":"Importance of individualizing treatment decisions in girls with central precocious puberty when initiating treatment after age 7 years or continuing beyond a chronological age of 10 years or a bone age of 12 years","volume":"34","year":"2021","journal-title":"Journal of Pediatric Endocrinology and Metabolism"},{"issue":"2","key":"key20240624150347_R56","first-page":"131","article-title":"Adequacy of basal luteinizing hormone levels in the diagnosis of central precocious puberty","volume":"55","year":"2020","journal-title":"Turkish Archives of Pediatrics"},{"key":"key20240624150347_R57","first-page":"241","volume-title":"Gender Differences at Puberty","year":"2003"},{"key":"key20240624150347_R58","first-page":"1","volume-title":"Handbook of Research on Play Specialism Strategies to Prevent Pediatric Hospitalization Trauma","year":"2023"},{"key":"key20240624150347_R59","first-page":"1053","article-title":"Cognitive, emotional, and psychosocial functioning of girls treated with pharmacological puberty blockage for idiopathic central precocious puberty","volume":"7","year":"2016","journal-title":"Frontiers in Psychology"},{"key":"key20240624150347_R60","doi-asserted-by":"crossref","first-page":"104","DOI":"10.3389\/fphar.2019.00104","article-title":"Pelvic ultrasound in diagnosing and evaluating the efficacy of gonadotropin-releasing hormone agonist therapy in girls with idiopathic central precocious puberty","volume":"10","year":"2019","journal-title":"Frontiers in Pharmacology"},{"issue":"10","key":"key20240624150347_R61","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1515\/jpem-2019-0108","article-title":"Psychological effects of gonadotropin-releasing hormone agonist treatment in girls with central precocious puberty","volume":"32","year":"2019","journal-title":"Journal of Paediatric Endocrinology and Metabolism"},{"issue":"2","key":"key20240624150347_R62","first-page":"121","article-title":"Diagnostic value of urinary luteinizing hormone levels in the monitoring of precocious puberty treatment","volume":"64","year":"2020","journal-title":"Archives of Endocrinology and Metabolism"},{"key":"key20240624150347_R63","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/B978-0-12-407822-2.00002-5","volume-title":"Practical Pediatric Endocrinology in a Limited Resource Setting","year":"2013"},{"issue":"Suppl 1","key":"key20240624150347_R64","first-page":"S88","article-title":"PDG10 Cost-effectiveness analysis of GnRH analogue ALONE versus combined growth hormone for girls with central precocious puberty","volume":"24","year":"2021","journal-title":"Value in Health"}],"container-title":["Nursing Children and Young People"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.rcni.com\/doi\/pdf\/10.7748\/ncyp.2024.e1492","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T06:51:34Z","timestamp":1720075894000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.rcni.com\/doi\/10.7748\/ncyp.2024.e1492"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,8]]},"references-count":64,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2024,1,8]]},"published-print":{"date-parts":[[2024,7,4]]}},"alternative-id":["10.7748\/ncyp.2024.e1492"],"URL":"https:\/\/doi.org\/10.7748\/ncyp.2024.e1492","relation":{},"ISSN":["2046-2336","2046-2344"],"issn-type":[{"value":"2046-2336","type":"print"},{"value":"2046-2344","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,8]]}}}