{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:40:37Z","timestamp":1790811637703,"version":"4.1.0"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,24]]},"DOI":"10.7759\/cureus.100026","type":"journal-article","created":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T21:57:20Z","timestamp":1766613440000},"source":"Crossref","is-referenced-by-count":2,"title":["Atypical Appendicitis Presenting as Left Upper Quadrant Pain: A Case Report"],"prefix":"10.7759","author":[{"given":"Elisabeth","family":"Hildenbrandt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark E","family":"Hoffman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Salib","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Salib","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederick","family":"Tiesenga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.20502","article-title":"Diagnosis and management of acute appendicitis in adults: a review","volume":"326","author":"Moris D","year":"2021","unstructured":"Moris D, Paulson EK, Pappas TN. Diagnosis and management of acute appendicitis in adults: a review. JAMA. 2021, 326:2299-311. 10.1001\/jama.2021.20502","journal-title":"JAMA"},{"key":"ref2","article-title":"Huge atypical appendicitis in a 14-year-old male: a case report","volume":"5","author":"Rezaee Azandaryani A","year":"2016","unstructured":"Rezaee Azandaryani A, Eftekharian M, Mousavi M, Ebrahimi L. Huge atypical appendicitis in a 14-year-old male: a case report. Case Rep Clin Med. 2016, 5:341-5.","journal-title":"Case Rep Clin Med"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.15.3576","article-title":"Ascending retrocecal appendicitis presenting with right upper abdominal pain: utility of computed tomography","volume":"15","author":"Ong EM","year":"2009","unstructured":"Ong EM, Venkatesh SK. Ascending retrocecal appendicitis presenting with right upper abdominal pain: utility of computed tomography. World J Gastroenterol. 2009, 15:3576-9. 10.3748\/wjg.15.3576","journal-title":"World J Gastroenterol"},{"key":"ref4","doi-asserted-by":"crossref","DOI":"10.1001\/archsurg.1938.01190230008002","article-title":"Acute retrocecal appendicitis: based on seven hundred and fifty-one instances","volume":"36","author":"Collins DC","year":"1938","unstructured":"Collins DC. Acute retrocecal appendicitis: based on seven hundred and fifty-one instances. Arch Surg. 1938, 36:729-43.","journal-title":"Arch Surg"},{"key":"ref5","article-title":"The position of the vermiform appendix as ascertained by an analysis of 10,000 cases","volume":"67","author":"Wakeley CP","year":"1933","unstructured":"Wakeley CP. The position of the vermiform appendix as ascertained by an analysis of 10,000 cases. J Anat. 1933, 67:277-83.","journal-title":"J Anat"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.5114\/pjr.2023.131074","article-title":"Computed tomography evaluation of variations in positions and measurements of appendix in patients with non-appendicular symptoms: time to revise the diagnostic criteria for appendicitis","volume":"88","author":"Singh N","year":"2023","unstructured":"Singh N, Agrawal P, Singh DK, Agrawal GR. Computed tomography evaluation of variations in positions and measurements of appendix in patients with non-appendicular symptoms: time to revise the diagnostic criteria for appendicitis. Pol J Radiol. 2023, 88:e407-14. 10.5114\/pjr.2023.131074","journal-title":"Pol J Radiol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1089\/sur.2011.135","article-title":"Bacteriology of acute appendicitis and its implication for the use of prophylactic antibiotics","volume":"13","author":"Chen CY","year":"2012","unstructured":"Chen CY, Chen YC, Pu HN, Tsai CH, Chen WT, Lin CH. Bacteriology of acute appendicitis and its implication for the use of prophylactic antibiotics. Surg Infect (Larchmt). 2012, 13:383-90. 10.1089\/sur.2011.135","journal-title":"Surg Infect (Larchmt)"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2023.1104817","article-title":"Referred pain: characteristics, possible mechanisms, and clinical management","volume":"14","author":"Jin Q","year":"2023","unstructured":"Jin Q, Chang Y, Lu C, Chen L, Wang Y. Referred pain: characteristics, possible mechanisms, and clinical management. Front Neurol. 2023, 14:1104817. 10.3389\/fneur.2023.1104817","journal-title":"Front Neurol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.62181","article-title":"Acute appendicitis presenting as left flank pain: a case report","volume":"16","author":"Badawy I","year":"2024","unstructured":"Badawy I, Mbaya K, Metwally H. Acute appendicitis presenting as left flank pain: a case report. Cureus. 2024, 16:e62181. 10.7759\/cureus.62181","journal-title":"Cureus"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.98002","article-title":"Subhepatic appendicitis: a systematic review of clinical presentation, diagnostic challenges, and surgical management","volume":"17","author":"Shivalingam Vanaraj N","year":"2025","unstructured":"Shivalingam Vanaraj N, GV V, Vijayakumar K, et al.. Subhepatic appendicitis: a systematic review of clinical presentation, diagnostic challenges, and surgical management. Cureus. 2025, 17:e98002. 10.7759\/cureus.98002","journal-title":"Cureus"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.37024","article-title":"Typical and atypical presentations of appendicitis and their implications for diagnosis and treatment: a literature review","volume":"15","author":"Echevarria S","year":"2023","unstructured":"Echevarria S, Rauf F, Hussain N, et al.. Typical and atypical presentations of appendicitis and their implications for diagnosis and treatment: a literature review. Cureus. 2023, 15:e37024. 10.7759\/cureus.37024","journal-title":"Cureus"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.185.2.01850406","article-title":"CT evaluation of appendicitis and its complications: imaging techniques and key diagnostic findings","volume":"185","author":"Pinto Leite N","year":"2005","unstructured":"Pinto Leite N, Pereira JM, Cunha R, Pinto P, Sirlin C. CT evaluation of appendicitis and its complications: imaging techniques and key diagnostic findings. AJR Am J Roentgenol. 2005, 185:406-17. 10.2214\/ajr.185.2.01850406","journal-title":"AJR Am J Roentgenol"},{"key":"ref13","article-title":"Comparison of graded compression ultrasonography and unenhanced spiral computed tomography in the diagnosis of acute appendicitis","volume":"48","author":"Gamanagatti S","year":"2007","unstructured":"Gamanagatti S, Vashisht S, Kapoor A, Chumber S, Bal S. Comparison of graded compression ultrasonography and unenhanced spiral computed tomography in the diagnosis of acute appendicitis. Singapore Med J. 2007, 48:80-7.","journal-title":"Singapore Med J"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ogc.2014.06.002","article-title":"Gastrointestinal causes of abdominal pain","volume":"41","author":"Marsicano E","year":"2014","unstructured":"Marsicano E, Vuong GM, Prather CM. Gastrointestinal causes of abdominal pain. Obstet Gynecol Clin North Am. 2014, 41:465-89. 10.1016\/j.ogc.2014.06.002","journal-title":"Obstet Gynecol Clin North Am"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-023-10456-5","article-title":"Diagnosis and treatment of appendicitis: systematic review and meta-analysis","volume":"37","author":"Lamm R","year":"2023","unstructured":"Lamm R, Kumar SS, Collings AT, et al.. Diagnosis and treatment of appendicitis: systematic review and meta-analysis. Surg Endosc. 2023, 37:8933-90. 10.1007\/s00464-023-10456-5","journal-title":"Surg Endosc"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2014320","article-title":"A randomized trial comparing antibiotics with appendectomy for appendicitis","volume":"383","author":"Flum DR","year":"2020","unstructured":"Flum DR, Davidson GH, Monsell SE, et al.. A randomized trial comparing antibiotics with appendectomy for appendicitis. N Engl J Med. 2020, 383:1907-19. 10.1056\/NEJMoa2014320","journal-title":"N Engl J Med"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/314726-atypical-appendicitis-presenting-as-left-upper-quadrant-pain-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T21:57:21Z","timestamp":1766613441000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/314726-atypical-appendicitis-presenting-as-left-upper-quadrant-pain-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,24]]},"references-count":16,"URL":"https:\/\/doi.org\/10.7759\/cureus.100026","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12,24]]}}}