{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,27]],"date-time":"2025-12-27T04:48:59Z","timestamp":1766810939729,"version":"3.48.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,26]]},"DOI":"10.7759\/cureus.100157","type":"journal-article","created":{"date-parts":[[2025,12,27]],"date-time":"2025-12-27T03:41:13Z","timestamp":1766806873000},"source":"Crossref","is-referenced-by-count":0,"title":["Effect of Non-surgical Periodontal Therapy on the Salivary Resistin Level in Obese and Non-obese Individuals With Periodontitis"],"prefix":"10.7759","author":[{"given":"Shijna","family":"Ashraf","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. Santhosh","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rekha  P","family":"Radhakrishnan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R M","family":"Baiju","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nebu","family":"George","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neethu P","family":"Reghu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tony","family":"Kurien","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeswin","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/00003081-200212000-00016","article-title":"Managing overweight and obesity in women","volume":"45","author":"Klauer J","year":"2002","unstructured":"Klauer J, Aronne LJ. Managing overweight and obesity in women. Clin Obstet Gynecol. 2002, 45:1080-8. 10.1097\/00003081-200212000-00016","journal-title":"Clin Obstet Gynecol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyu061","article-title":"Commentary: origins and evolution of body mass index (BMI): continuing saga","volume":"43","author":"Blackburn H","year":"2014","unstructured":"Blackburn H, Jacobs D Jr. Commentary: origins and evolution of body mass index (BMI): continuing saga. Int J Epidemiol. 2014, 43:665-9. 10.1093\/ije\/dyu061","journal-title":"Int J Epidemiol"},{"key":"ref3","article-title":"Obesity: preventing and managing the global epidemic. Report of a WHO consultation","volume":"894","year":"2000","unstructured":"Obesity. preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ Tech Rep Ser. 2000, 894:1-253.","journal-title":"World Health Organ Tech Rep Ser"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0803193","article-title":"Body mass index and all-cause mortality in a nationwide US cohort","volume":"30","author":"Freedman DM","year":"2006","unstructured":"Freedman DM, Ron E, Ballard-Barbash R, Doody MM, Linet MS. Body mass index and all-cause mortality in a nationwide US cohort. Int J Obes (Lond). 2006, 30:822-9. 10.1038\/sj.ijo.0803193","journal-title":"Int J Obes (Lond)"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13769","article-title":"Prevalence of periodontitis in dentate people between 2011 and 2020: a systematic review and meta-analysis of epidemiological studies","volume":"50","author":"Trindade D","year":"2023","unstructured":"Trindade D, Carvalho R, Machado V, Chambrone L, Mendes JJ, Botelho J. Prevalence of periodontitis in dentate people between 2011 and 2020: a systematic review and meta-analysis of epidemiological studies. J Clin Periodontol. 2023, 50:604-26. 10.1111\/jcpe.13769","journal-title":"J Clin Periodontol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1590\/0103-6440201300019","article-title":"Relationship between periodontal disease and obesity: the role of life-course events","volume":"25","author":"Nascimento GG","year":"2014","unstructured":"Nascimento GG, Leite FR, Correa MB, Horta BL, Peres MA, Demarco FF. Relationship between periodontal disease and obesity: the role of life-course events. Braz Dent J. 2014, 25:87-9. 10.1590\/0103-6440201300019","journal-title":"Braz Dent J"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199808133390717","article-title":"Obesity and periodontitis","volume":"339","author":"Saito T","year":"1998","unstructured":"Saito T, Shimazaki Y, Sakamoto M. Obesity and periodontitis. N Engl J Med. 1998, 339:482-3. 10.1056\/NEJM199808133390717","journal-title":"N Engl J Med"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.4103\/0972-124X.70827","article-title":"Obesity and periodontal disease","volume":"14","author":"Jagannathachary S","year":"2010","unstructured":"Jagannathachary S, Kamaraj D. Obesity and periodontal disease. J Indian Soc Periodontol. 2010, 14:96-100. 10.4103\/0972-124X.70827","journal-title":"J Indian Soc Periodontol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1038\/35053000","article-title":"The hormone resistin links obesity to diabetes","volume":"409","author":"Steppan CM","year":"2001","unstructured":"Steppan CM, Bailey ST, Bhat S, et al.. The hormone resistin links obesity to diabetes. Nature. 2001, 409:307-12. 10.1038\/35053000","journal-title":"Nature"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.2011.01369.x","article-title":"Resistin: functional roles and therapeutic considerations for cardiovascular disease","volume":"165","author":"Jamaluddin MS","year":"2012","unstructured":"Jamaluddin MS, Weakley SM, Yao Q, Chen C. Resistin: functional roles and therapeutic considerations for cardiovascular disease. Br J Pharmacol. 2012, 165:622-32. 10.1111\/j.1476-5381.2011.01369.x","journal-title":"Br J Pharmacol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/930206","article-title":"Resistin: a potential biomarker for periodontitis influenced diabetes mellitus and diabetes induced periodontitis","volume":"2014","author":"Devanoorkar A","year":"2014","unstructured":"Devanoorkar A, Kathariya R, Guttiganur N, Gopalakrishnan D, Bagchi P. Resistin: a potential biomarker for periodontitis influenced diabetes mellitus and diabetes induced periodontitis. Dis Markers. 2014, 2014:930206. 10.1155\/2014\/930206","journal-title":"Dis Markers"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/359724","article-title":"Measurement of salivary resistin level in patients with type 2 diabetes","volume":"2012","author":"Yin J","year":"2012","unstructured":"Yin J, Gao H, Yang J, Xu L, Li M. Measurement of salivary resistin level in patients with type 2 diabetes. Int J Endocrinol. 2012, 2012:359724. 10.1155\/2012\/359724","journal-title":"Int J Endocrinol"},{"key":"ref13","article-title":"Estimation of serum and salivary level of resistin in obese patients with periodontitis","volume":"7","author":"Rao RM","year":"2016","unstructured":"Rao RM, Shenoy N, Thomas B. Estimation of serum and salivary level of resistin in obese patients with periodontitis. Indian J Oral Sci. 2016, 7:87-91.","journal-title":"Indian J Oral Sci"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/jicd.12314","article-title":"Non-surgical periodontal therapy reduces salivary adipocytokines in chronic periodontitis patients with and without obesity","volume":"9","author":"Al-Hamoudi N","year":"2018","unstructured":"Al-Hamoudi N, Abduljabbar T, Mirza S, Al-Sowygh ZH, Vohra F, Javed F, Akram Z. Non-surgical periodontal therapy reduces salivary adipocytokines in chronic periodontitis patients with and without obesity. J Investig Clin Dent. 2018, 9:e12314. 10.1111\/jicd.12314","journal-title":"J Investig Clin Dent"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)15268-3","article-title":"Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies","volume":"363","year":"2004","unstructured":"Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet. 2004, 363.157-63. 10.1016\/S0140-6736(03)15268-3","journal-title":"Lancet"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1972.43.1.38","article-title":"The plaque control record","volume":"43","author":"O'Leary TJ","year":"1972","unstructured":"O'Leary TJ, Drake RB, Naylor JE. The plaque control record. J Periodontol. 1972, 43:38. 10.1902\/jop.1972.43.1.38","journal-title":"J Periodontol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(77)90055-x","article-title":"Influence of obesity and hypertension on the severity of periodontitis in rats","volume":"43","author":"Perlstein MI","year":"1977","unstructured":"Perlstein MI, Bissada NF. Influence of obesity and hypertension on the severity of periodontitis in rats. Oral Surg Oral Med Oral Pathol. 1977, 43:707-19. 10.1016\/0030-4220(77)90055-x","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1177\/00220345010800070701","article-title":"Relationship between upper body obesity and periodontitis","volume":"80","author":"Saito T","year":"2001","unstructured":"Saito T, Shimazaki Y, Koga T, Tsuzuki M, Ohshima A. Relationship between upper body obesity and periodontitis. J Dent Res. 2001, 80:1631-6. 10.1177\/00220345010800070701","journal-title":"J Dent Res"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.11-S.2075","article-title":"A proposed model linking inflammation to obesity, diabetes, and periodontal infections","volume":"76","author":"Genco RJ","year":"2005","unstructured":"Genco RJ, Grossi SG, Ho A, Nishimura F, Murayama Y. A proposed model linking inflammation to obesity, diabetes, and periodontal infections. J Periodontol. 2005, 76:2075-84. 10.1902\/jop.2005.76.11-S.2075","journal-title":"J Periodontol"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.21786","article-title":"Association between obesity and periodontal disease. A systematic review of epidemiological studies and controlled clinical trials","volume":"22","author":"Martinez-Herrera M","year":"2017","unstructured":"Martinez-Herrera M, Silvestre-Rangil J, Silvestre FJ. Association between obesity and periodontal disease. A systematic review of epidemiological studies and controlled clinical trials. Med Oral Patol Oral Cir Bucal. 2017, 22:e708-15. 10.4317\/medoral.21786","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.999455","article-title":"Obesity and periodontitis: a systematic review and updated meta-analysis","volume":"13","author":"Kim CM","year":"2022","unstructured":"Kim CM, Lee S, Hwang W, Son E, Kim TW, Kim K, Kim YH. Obesity and periodontitis: a systematic review and updated meta-analysis. Front Endocrinol (Lausanne). 2022, 13:999455. 10.3389\/fendo.2022.999455","journal-title":"Front Endocrinol (Lausanne)"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1042\/CS20200895","article-title":"The complex role of adipokines in obesity, inflammation, and autoimmunity","volume":"135","author":"Taylor EB","year":"2021","unstructured":"Taylor EB. The complex role of adipokines in obesity, inflammation, and autoimmunity. Clin Sci (Lond). 2021, 135:731-52. 10.1042\/CS20200895","journal-title":"Clin Sci (Lond)"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.4239\/wjd.v12.i9.1507","article-title":"Salivary resistin level and its association with insulin resistance in obese individuals","volume":"12","author":"Abdalla MM","year":"2021","unstructured":"Abdalla MM. Salivary resistin level and its association with insulin resistance in obese individuals. World J Diabetes. 2021, 12:1507-17. 10.4239\/wjd.v12.i9.1507","journal-title":"World J Diabetes"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/4801418","article-title":"Cytokine profile in chronic periodontitis patients with and without obesity: a systematic review and meta-analysis","volume":"2016","author":"Akram Z","year":"2016","unstructured":"Akram Z, Abduljabbar T, Abu Hassan MI, Javed F, Vohra F. Cytokine profile in chronic periodontitis patients with and without obesity: a systematic review and meta-analysis. Dis Markers. 2016, 2016:4801418. 10.1155\/2016\/4801418","journal-title":"Dis Markers"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.2334\/josnusd.16-0127","article-title":"Effect of nonsurgical periodontal treatment on clinical periodontal variables and salivary resistin levels in obese Asians","volume":"59","author":"Akram Z","year":"2017","unstructured":"Akram Z, Baharuddin NA, Vaithilingam RD, et al.. Effect of nonsurgical periodontal treatment on clinical periodontal variables and salivary resistin levels in obese Asians. J Oral Sci. 2017, 59:93-102. 10.2334\/josnusd.16-0127","journal-title":"J Oral Sci"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.4103\/jisp.jisp_108_18","article-title":"Effect of nonsurgical periodontal therapy on plasma-reactive oxygen metabolite and gingival crevicular fluid resistin and serum resistin levels in obese and normal weight individuals with chronic periodontitis","volume":"22","author":"Suresh S","year":"2018","unstructured":"Suresh S, Mahendra J, Singh G, Pradeep Kumar AR, Thilagar S, Rao N. Effect of nonsurgical periodontal therapy on plasma-reactive oxygen metabolite and gingival crevicular fluid resistin and serum resistin levels in obese and normal weight individuals with chronic periodontitis. J Indian Soc Periodontol. 2018, 22:310-6. 10.4103\/jisp.jisp_108_18","journal-title":"J Indian Soc Periodontol"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.11-S.2168","article-title":"Resolution of inflammation in periodontitis","volume":"76","author":"Kantarci A","year":"2005","unstructured":"Kantarci A, Van Dyke TE. Resolution of inflammation in periodontitis. J Periodontol. 2005, 76:2168-74. 10.1902\/jop.2005.76.11-S.2168","journal-title":"J Periodontol"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12396","article-title":"Local and serum levels of adipokines in patients with obesity after periodontal therapy: one-year follow-up","volume":"42","author":"Gon\u00e7alves TE","year":"2015","unstructured":"Gon\u00e7alves TE, Zimmermann GS, Figueiredo LC, et al.. Local and serum levels of adipokines in patients with obesity after periodontal therapy: one-year follow-up. J Clin Periodontol. 2015, 42:431-9. 10.1111\/jcpe.12396","journal-title":"J Clin Periodontol"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2014.140266","article-title":"Effects of scaling and root planing on clinical response and serum levels of adipocytokines in patients with obesity and chronic periodontitis","volume":"86","author":"Gon\u00e7alves TE","year":"2015","unstructured":"Gon\u00e7alves TE, Feres M, Zimmermann GS, Faveri M, Figueiredo LC, Braga PG, Duarte PM. Effects of scaling and root planing on clinical response and serum levels of adipocytokines in patients with obesity and chronic periodontitis. J Periodontol. 2015, 86:53-61. 10.1902\/jop.2014.140266","journal-title":"J Periodontol"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/153418","article-title":"Evaluation of serum resistin levels in periodontal health and disease and effects of non surgical periodontal therapy on its levels","volume":"32","author":"Devanoorkar A","year":"2012","unstructured":"Devanoorkar A, Dwarakanath CD, Gundanavar G, Kathariya R, Patil SR. Evaluation of serum resistin levels in periodontal health and disease and effects of non surgical periodontal therapy on its levels. Dis Markers. 2012, 32:289-94. 10.1155\/2012\/153418","journal-title":"Dis Markers"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-016-0272-2","article-title":"Influence of obesity on the outcome of non-surgical periodontal therapy - a systematic review","volume":"16","author":"Gerber FA","year":"2016","unstructured":"Gerber FA, Sahrmann P, Schmidlin OA, Heumann C, Beer JH, Schmidlin PR. Influence of obesity on the outcome of non-surgical periodontal therapy - a systematic review. BMC Oral Health. 2016, 16:90. 10.1186\/s12903-016-0272-2","journal-title":"BMC Oral Health"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/440654-effect-of-non-surgical-periodontal-therapy-on-the-salivary-resistin-level-in-obese-and-non-obese-individuals-with-periodontitis","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,27]],"date-time":"2025-12-27T03:41:19Z","timestamp":1766806879000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/440654-effect-of-non-surgical-periodontal-therapy-on-the-salivary-resistin-level-in-obese-and-non-obese-individuals-with-periodontitis"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,26]]},"references-count":31,"URL":"https:\/\/doi.org\/10.7759\/cureus.100157","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12,26]]}}}