{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T19:12:56Z","timestamp":1791313976245,"version":"4.3.1"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,30]]},"DOI":"10.7759\/cureus.100431","type":"journal-article","created":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T18:36:56Z","timestamp":1767119816000},"source":"Crossref","is-referenced-by-count":1,"title":["Role of Perfusion Index as a Predictor of Vasopressor Requirement in Patients With Sepsis"],"prefix":"10.7759","author":[{"given":"Mirza","family":"Nahiduzzaman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suman","family":"Kundu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manas K","family":"Mazumder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MD T","family":"Islam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shubamay D","family":"Nath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajeebshankar","family":"Karmakar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masnoon Ahmed","family":"Noor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1177\/2050312119835043","article-title":"Sepsis: the evolution in definition, pathophysiology, and management","volume":"7","author":"Gyawali B","year":"2019","unstructured":"Gyawali B, Ramakrishna K, Dhamoon AS. Sepsis: the evolution in definition, pathophysiology, and management. SAGE Open Med. 2019, 7:2050312119835043. 10.1177\/2050312119835043","journal-title":"SAGE Open Med"},{"key":"ref2","article-title":"Sepsis management","author":"Lee YR","year":"2024","unstructured":"Lee YR, Bainum TB. Sepsis management. Critical Care Self-Assessment Program (CCSAP) Book 1. Smith ZR, Zimmerman LH (ed): American College of Clinical Pharmacy (ACCP), 2024. 1:7-33."},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(14)70061-X","article-title":"Assessment of the worldwide burden of critical illness: the intensive care over nations (ICON) audit","volume":"2","author":"Vincent J-L","year":"2014","unstructured":"Vincent J-L, Marshall JC, \u00d1amendys-Silva SA, et al.. Assessment of the worldwide burden of critical illness: the intensive care over nations (ICON) audit. Lancet Respir Med. 2014, 2:380-6. 10.1016\/S2213-2600(14)70061-X","journal-title":"Lancet Respir Med"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/SHK.0000000000000481","article-title":"Evaluation of perfusion index as a predictor of vasopressor requirement in patients with severe sepsis","volume":"44","author":"Rasmy I","year":"2015","unstructured":"Rasmy I, Mohamed H, Nabil N, et al.. Evaluation of perfusion index as a predictor of vasopressor requirement in patients with severe sepsis. Shock. 2015, 44:554-9. 10.1097\/SHK.0000000000000481","journal-title":"Shock"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31827e83af","article-title":"Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012","volume":"41","author":"Dellinger RP","year":"2013","unstructured":"Dellinger RP, Levy MM, Rhodes A, et al.. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med. 2013, 41:580-637. 10.1097\/CCM.0b013e31827e83af","journal-title":"Crit Care Med"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-017-4683-6","article-title":"Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock: 2016","volume":"43","author":"Rhodes A","year":"2017","unstructured":"Rhodes A, Evans LE, Alhazzani W, et al.. Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock: 2016. Intensive Care Med. 2017, 43:304-77. 10.1007\/s00134-017-4683-6","journal-title":"Intensive Care Med"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-018-5085-0","article-title":"The Surviving Sepsis Campaign bundle: 2018 update","volume":"44","author":"Levy MM","year":"2018","unstructured":"Levy MM, Evans LE, Rhodes A. The Surviving Sepsis Campaign bundle: 2018 update. Intensive Care Med. 2018, 44:925-8. 10.1007\/s00134-018-5085-0","journal-title":"Intensive Care Med"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-017-5016-5","article-title":"Pooled analysis of higher versus lower blood pressure targets for vasopressor therapy septic and vasodilatory shock","volume":"44","author":"Lamontagne F","year":"2018","unstructured":"Lamontagne F, Day AG, Meade MO, et al.. Pooled analysis of higher versus lower blood pressure targets for vasopressor therapy septic and vasodilatory shock. Intensive Care Med. 2018, 44:12-21. 10.1007\/s00134-017-5016-5","journal-title":"Intensive Care Med"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1186\/s40560-017-0220-5","article-title":"Perfusion indices revisited","volume":"5","author":"Hasanin A","year":"2017","unstructured":"Hasanin A, Mukhtar A, Nassar H. Perfusion indices revisited. J Intensive Care. 2017, 5:24. 10.1186\/s40560-017-0220-5","journal-title":"J Intensive Care"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1186\/cc8011","article-title":"Low tissue oxygen saturation at the end of early goal-directed therapy is associated with worse outcome in critically ill patients","volume":"13 Suppl 5","author":"Lima A","year":"2009","unstructured":"Lima A, van Bommel J, Jansen TC, Ince C, Bakker J. Low tissue oxygen saturation at the end of early goal-directed therapy is associated with worse outcome in critically ill patients. Crit Care. 2009, 13 Suppl 5:S13. 10.1186\/cc8011","journal-title":"Crit Care"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1681.1989.tb01578.x","article-title":"Observations on a new non-invasive monitor of skin blood flow","volume":"16","author":"Hales JR","year":"1989","unstructured":"Hales JR, Stephens FR, Fawcett AA, Daniel K, Sheahan J, Westerman RA, James SB. Observations on a new non-invasive monitor of skin blood flow. Clin Exp Pharmacol Physiol. 1989, 16:403-15. 10.1111\/j.1440-1681.1989.tb01578.x","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-021-06506-y","article-title":"Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2021","volume":"47","author":"Evans L","year":"2021","unstructured":"Evans L, Rhodes A, Alhazzani W, et al.. Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2021. Intensive Care Med. 2021, 47:1181-247. 10.1007\/s00134-021-06506-y","journal-title":"Intensive Care Med"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2011.08.002","article-title":"Endothelial dysfunction assessed by brachial artery ultrasound in severe sepsis and septic shock","volume":"27","author":"Becker L","year":"2012","unstructured":"Becker L, Prado K, Foppa M, et al.. Endothelial dysfunction assessed by brachial artery ultrasound in severe sepsis and septic shock. J Crit Care. 2012, 27:316.e9-14. 10.1016\/j.jcrc.2011.08.002","journal-title":"J Crit Care"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2012.01.005","article-title":"Prevalence and characteristics of nonlactate and lactate expressors in septic shock","volume":"27","author":"Dugas AF","year":"2012","unstructured":"Dugas AF, Mackenhauer J, Salciccioli JD, Cocchi MN, Gautam S, Donnino MW. Prevalence and characteristics of nonlactate and lactate expressors in septic shock. J Crit Care. 2012, 27:344-50. 10.1016\/j.jcrc.2012.01.005","journal-title":"J Crit Care"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097\/01.ccm.0000138558.16257.3f","article-title":"Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock","volume":"32","author":"Sakr Y","year":"2004","unstructured":"Sakr Y, Dubois MJ, De Backer D, Creteur J, Vincent JL. Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock. Crit Care Med. 2004, 32:1825-31. 10.1097\/01.ccm.0000138558.16257.3f","journal-title":"Crit Care Med"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.01237.2006","article-title":"Impairments in microvascular reactivity are related to organ failure in human sepsis","volume":"293","author":"Doerschug KC","year":"2007","unstructured":"Doerschug KC, Delsing AS, Schmidt GA, Haynes WG. Impairments in microvascular reactivity are related to organ failure in human sepsis. Am J Physiol Heart Circ Physiol. 2007, 293:H1065-71. 10.1152\/ajpheart.01237.2006","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1097\/SHK.0b013e318298836d","article-title":"Characteristics and outcomes of patients with vasoplegic versus tissue dysoxic septic shock","volume":"40","author":"Sterling SA","year":"2013","unstructured":"Sterling SA, Puskarich MA, Shapiro NI, Trzeciak S, Kline JA, Summers RL, Jones AE. Characteristics and outcomes of patients with vasoplegic versus tissue dysoxic septic shock. Shock. 2013, 40:11-4. 10.1097\/SHK.0b013e318298836d","journal-title":"Shock"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1186\/s13613-015-0058-8","article-title":"Timing and causes of death in septic shock","volume":"5","author":"Daviaud F","year":"2015","unstructured":"Daviaud F, Grimaldi D, Dechartres A, et al.. Timing and causes of death in septic shock. Ann Intensive Care. 2015, 5:16. 10.1186\/s13613-015-0058-8","journal-title":"Ann Intensive Care"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200206000-00006","article-title":"Use of a peripheral perfusion index derived from the pulse oximetry signal as a noninvasive indicator of perfusion","volume":"30","author":"Lima AP","year":"2002","unstructured":"Lima AP, Beelen P, Bakker J. Use of a peripheral perfusion index derived from the pulse oximetry signal as a noninvasive indicator of perfusion. Crit Care Med. 2002, 30:1210-3. 10.1097\/00003246-200206000-00006","journal-title":"Crit Care Med"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/438393-role-of-perfusion-index-as-a-predictor-of-vasopressor-requirement-in-patients-with-sepsis","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T18:36:56Z","timestamp":1767119816000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/438393-role-of-perfusion-index-as-a-predictor-of-vasopressor-requirement-in-patients-with-sepsis"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,30]]},"references-count":19,"URL":"https:\/\/doi.org\/10.7759\/cureus.100431","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12,30]]}}}