{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T16:55:11Z","timestamp":1767200111534,"version":"3.48.0"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,31]]},"DOI":"10.7759\/cureus.100502","type":"journal-article","created":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T16:31:05Z","timestamp":1767198665000},"source":"Crossref","is-referenced-by-count":0,"title":["Limitations of Oral Mucosal Moisture Assessment as an Indicator of Intravascular Dehydration in Postoperative Cardiovascular Surgical Patients in the ICU: A Prospective Pilot Diagnostic Accuracy Study"],"prefix":"10.7759","author":[{"given":"Toshiharu","family":"Nakama","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takafumi","family":"Todaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chihaya","family":"Uehara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takumi","family":"Furugen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsunobu","family":"Toyosaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD009647.pub2","article-title":"Clinical symptoms, signs and tests for identification of impending and current water\u2010loss dehydration in older people","volume":"2015","author":"Hooper L","year":"2015","unstructured":"Hooper L, Abdelhamid A, Attreed NJ, et al.. Clinical symptoms, signs and tests for identification of impending and current water\u2010loss dehydration in older people. Cochrane Database Syst Rev. 2015, 2015:CD009647. 10.1002\/14651858.CD009647.pub2","journal-title":"Cochrane Database Syst Rev"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/cre2.145","article-title":"A pilot clinical evaluation of oral mucosal dryness in dehydrated patients using a moisture-checking device","volume":"5","author":"Fukushima Y","year":"2019","unstructured":"Fukushima Y, Sano Y, Isozaki Y, et al.. A pilot clinical evaluation of oral mucosal dryness in dehydrated patients using a moisture-checking device. Clin Exp Dent Res. 2019, 5:116-20. 10.1002\/cre2.145","journal-title":"Clin Exp Dent Res"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/s1348-8643(17)30017-4","article-title":"Evaluation of oral wetness using an improved moisture\u2010checking device for the diagnosis of dry mouth","volume":"14","author":"Fukushima Y","year":"2017","unstructured":"Fukushima Y, Yoda T, Araki R, et al.. Evaluation of oral wetness using an improved moisture\u2010checking device for the diagnosis of dry mouth. Oral Sci Int. 2017, 14:33-6. 10.1016\/s1348-8643(17)30017-4","journal-title":"Oral Sci Int"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3390\/geriatrics5020028","article-title":"Measurement of oral moisture on oral dryness patients","volume":"5","author":"Mizuhashi F","year":"2020","unstructured":"Mizuhashi F, Koide K, Toya S, Nashida T. Measurement of oral moisture on oral dryness patients. Geriatrics (Basel). 2020, 5:28. 10.3390\/geriatrics5020028","journal-title":"Geriatrics (Basel)"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.2186\/jjps.49.283","article-title":"The usefulness of an oral moisture checking device (Moisture Checker for Mucus) (Article in Japanese)","volume":"49","author":"Takahashi F","year":"2005","unstructured":"Takahashi F, Koji T, Morita O. The usefulness of an oral moisture checking device (Moisture Checker for Mucus) (Article in Japanese). Nihon Hotetsu Shika Gakkai Zasshi. 2005, 49:283-9. 10.2186\/jjps.49.283","journal-title":"Nihon Hotetsu Shika Gakkai Zasshi"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-019-0797-2","article-title":"Evaluate five different diagnostic tests for dry mouth assessment in geriatric residents in long-term institutions in Taiwan","volume":"19","author":"Cheng YM","year":"2019","unstructured":"Cheng YM, Lan SH, Hsieh YP, Lan SJ, Hsu SW. Evaluate five different diagnostic tests for dry mouth assessment in geriatric residents in long-term institutions in Taiwan. BMC Oral Health. 2019, 19:106. 10.1186\/s12903-019-0797-2","journal-title":"BMC Oral Health"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1080\/07853890.2019.1628352","article-title":"A multidisciplinary consensus on dehydration: definitions, diagnostic methods and clinical implications","volume":"51","author":"Lacey J","year":"2019","unstructured":"Lacey J, Corbett J, Forni L, et al.. A multidisciplinary consensus on dehydration: definitions, diagnostic methods and clinical implications. Ann Med. 2019, 51:232-51. 10.1080\/07853890.2019.1628352","journal-title":"Ann Med"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2011.02.395","article-title":"Volume depletion versus dehydration: how understanding the difference can guide therapy","volume":"58","author":"Bhave G","year":"2011","unstructured":"Bhave G, Neilson EG. Volume depletion versus dehydration: how understanding the difference can guide therapy. Am J Kidney Dis. 2011, 58:302-9. 10.1053\/j.ajkd.2011.02.395","journal-title":"Am J Kidney Dis"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1186\/s40635-023-00582-8","article-title":"Capillary leak and endothelial permeability in critically ill patients: a current overview","volume":"11","author":"Saravi B","year":"2023","unstructured":"Saravi B, Goebel U, Hassenzahl LO, et al.. Capillary leak and endothelial permeability in critically ill patients: a current overview. Intensive Care Med Exp. 2023, 11:96. 10.1186\/s40635-023-00582-8","journal-title":"Intensive Care Med Exp"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-012799","article-title":"STARD 2015 guidelines for reporting diagnostic accuracy studies: explanation and elaboration","volume":"6","author":"Cohen JF","year":"2016","unstructured":"Cohen JF, Korevaar DA, Altman DG, et al.. STARD 2015 guidelines for reporting diagnostic accuracy studies: explanation and elaboration. BMJ Open. 2016, 6:e012799. 10.1136\/bmjopen-2016-012799","journal-title":"BMJ Open"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1186\/s13089-020-00163-w","article-title":"Quantifying systemic congestion with Point-Of-Care ultrasound: development of the venous excess ultrasound grading system","volume":"12","author":"Beaubien-Souligny W","year":"2020","unstructured":"Beaubien-Souligny W, Rola P, Haycock K, Bouchard J, Lamarche Y, Spiegel R, Denault AY. Quantifying systemic congestion with Point-Of-Care ultrasound: development of the venous excess ultrasound grading system. Ultrasound J. 2020, 12:16. 10.1186\/s13089-020-00163-w","journal-title":"Ultrasound J"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/BF01709751","article-title":"The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction\/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine","volume":"22","author":"Vincent JL","year":"1996","unstructured":"Vincent JL, Moreno R, Takala J, et al.. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction\/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med. 1996, 22:707-10. 10.1007\/BF01709751","journal-title":"Intensive Care Med"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2017.02.94","article-title":"Echocardiography to guide fluid therapy in critically ill patients: check the heart and take a quick look at the lungs","volume":"9","author":"Franchi F","year":"2017","unstructured":"Franchi F, Vetrugno L, Scolletta S. Echocardiography to guide fluid therapy in critically ill patients: check the heart and take a quick look at the lungs. J Thorac Dis. 2017, 9:477-81. 10.21037\/jtd.2017.02.94","journal-title":"J Thorac Dis"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1053\/j.ackd.2021.02.003","article-title":"Inferior vena cava collapsibility index: clinical validation and application for assessment of relative intravascular volume","volume":"28","author":"Kaptein MJ","year":"2021","unstructured":"Kaptein MJ, Kaptein EM. Inferior vena cava collapsibility index: clinical validation and application for assessment of relative intravascular volume. Adv Chronic Kidney Dis. 2021, 28:218-26. 10.1053\/j.ackd.2021.02.003","journal-title":"Adv Chronic Kidney Dis"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0000000000002525","article-title":"Ultrasonographic inferior vena cava diameter response to trauma resuscitation after 1 hour predicts 24-hour fluid requirement","volume":"88","author":"Doucet JJ","year":"2020","unstructured":"Doucet JJ, Ferrada P, Murthi S, et al.. Ultrasonographic inferior vena cava diameter response to trauma resuscitation after 1 hour predicts 24-hour fluid requirement. J Trauma Acute Care Surg. 2020, 88:70-9. 10.1097\/TA.0000000000002525","journal-title":"J Trauma Acute Care Surg"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1080\/10903127.2020.1778823","article-title":"Inferior vena cava diameter is an early marker of central hypovolemia during simulated blood loss","volume":"25","author":"Johnson BD","year":"2021","unstructured":"Johnson BD, Schlader ZJ, Schaake MW, et al.. Inferior vena cava diameter is an early marker of central hypovolemia during simulated blood loss. Prehosp Emerg Care. 2021, 25:341-6. 10.1080\/10903127.2020.1778823","journal-title":"Prehosp Emerg Care"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-025-07975-1","article-title":"Central venous pressure: current uses and prospects for an old parameter","volume":"51","author":"Caplan M","year":"2025","unstructured":"Caplan M, Chew MS, Hamzaoui O. Central venous pressure: current uses and prospects for an old parameter. Intensive Care Med. 2025, 51:1363-6. 10.1007\/s00134-025-07975-1","journal-title":"Intensive Care Med"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-017-1796-9","article-title":"What is the impact of the fluid challenge technique on diagnosis of fluid responsiveness? A systematic review and meta-analysis","volume":"21","author":"Toscani L","year":"2017","unstructured":"Toscani L, Aya HD, Antonakaki D, et al.. What is the impact of the fluid challenge technique on diagnosis of fluid responsiveness? A systematic review and meta-analysis. Crit Care. 2017, 21:207. 10.1186\/s13054-017-1796-9","journal-title":"Crit Care"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-024-05078-9","article-title":"Assessment of fluid responsiveness using pulse pressure variation, stroke volume variation, plethysmographic variability index, central venous pressure, and inferior vena cava variation in patients undergoing mechanical ventilation: a systematic review and meta-analysis","volume":"28","author":"Chaves RC","year":"2024","unstructured":"Chaves RC, Barbas CS, Queiroz VN, et al.. Assessment of fluid responsiveness using pulse pressure variation, stroke volume variation, plethysmographic variability index, central venous pressure, and inferior vena cava variation in patients undergoing mechanical ventilation: a systematic review and meta-analysis. Crit Care. 2024, 28:289. 10.1186\/s13054-024-05078-9","journal-title":"Crit Care"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1186\/cc11368","article-title":"Fluid overload and changes in serum creatinine after cardiac surgery: predictors of mortality and longer intensive care stay. A prospective cohort study","volume":"16","author":"Stein A","year":"2012","unstructured":"Stein A, de Souza LV, Belettini CR, et al.. Fluid overload and changes in serum creatinine after cardiac surgery: predictors of mortality and longer intensive care stay. A prospective cohort study. Crit Care. 2012, 16:R99. 10.1186\/cc11368","journal-title":"Crit Care"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-015-1085-4","article-title":"Fluid balance and mortality in critically ill patients with acute kidney injury: a multicenter prospective epidemiological study","volume":"19","author":"Wang N","year":"2015","unstructured":"Wang N, Jiang L, Zhu B, Wen Y, Xi XM. Fluid balance and mortality in critically ill patients with acute kidney injury: a multicenter prospective epidemiological study. Crit Care. 2015, 19:371. 10.1186\/s13054-015-1085-4","journal-title":"Crit Care"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2012.244","article-title":"Investigation of the freely available easy-to-use software 'EZR' for medical statistics","volume":"48","author":"Kanda Y","year":"2013","unstructured":"Kanda Y. Investigation of the freely available easy-to-use software 'EZR' for medical statistics. Bone Marrow Transplant. 2013, 48:452-8. 10.1038\/bmt.2012.244","journal-title":"Bone Marrow Transplant"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1111\/j.1553-2712.1996.tb03538.x","article-title":"Statistical methodology: I. Incorporating the prevalence of disease into the sample size calculation for sensitivity and specificity","volume":"3","author":"Buderer NM","year":"1996","unstructured":"Buderer NM. Statistical methodology: I. Incorporating the prevalence of disease into the sample size calculation for sensitivity and specificity. Acad Emerg Med. 1996, 3:895-900. 10.1111\/j.1553-2712.1996.tb03538.x","journal-title":"Acad Emerg Med"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(1950)3:1<32::aid-cncr2820030106>3.0.co;2-3","article-title":"Index for rating diagnostic tests","volume":"3","author":"Youden WJ","year":"1950","unstructured":"Youden WJ. Index for rating diagnostic tests. Cancer. 1950, 3:32-5. 10.1002\/1097-0142(1950)3:1&lt;32::aid-cncr2820030106&gt;3.0.co;2-3","journal-title":"Cancer"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.7326\/M14-0698","article-title":"Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis (TRIPOD): explanation and elaboration","volume":"162","author":"Moons KG","year":"2015","unstructured":"Moons KG, Altman DG, Reitsma JB, et al.. Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis (TRIPOD): explanation and elaboration. Ann Intern Med. 2015, 162:W1-73. 10.7326\/M14-0698","journal-title":"Ann Intern Med"},{"key":"ref26","article-title":"Receiver operating characteristic (ROC) curve analysis for medical diagnostic test evaluation","volume":"4","author":"Hajian-Tilaki K","year":"2013","unstructured":"Hajian-Tilaki K. Receiver operating characteristic (ROC) curve analysis for medical diagnostic test evaluation. Caspian J Intern Med. 2013, 4:627-35.","journal-title":"Caspian J Intern Med"},{"key":"ref27","doi-asserted-by":"crossref","DOI":"10.1051\/ject\/201749174","article-title":"Endothelial glycocalyx and cardiopulmonary bypass","volume":"49","author":"Myers GJ","year":"2017","unstructured":"Myers GJ, Wegner J. Endothelial glycocalyx and cardiopulmonary bypass. J Extra Corpor Technol. 2017, 49:174-81.","journal-title":"J Extra Corpor Technol"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1111\/anae.16633","article-title":"Measurement and interpretation of central venous pressure: a narrative review","volume":"80","author":"Lloyd-Donald P","year":"2025","unstructured":"Lloyd-Donald P, Fujino M, Waldman B, Miles LF. Measurement and interpretation of central venous pressure: a narrative review. Anaesthesia. 2025, 80:1093-102. 10.1111\/anae.16633","journal-title":"Anaesthesia"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/434601-limitations-of-oral-mucosal-moisture-assessment-as-an-indicator-of-intravascular-dehydration-in-postoperative-cardiovascular-surgical-patients-in-the-icu-a-prospective-pilot-diagnostic-accuracy-study","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T16:31:06Z","timestamp":1767198666000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/434601-limitations-of-oral-mucosal-moisture-assessment-as-an-indicator-of-intravascular-dehydration-in-postoperative-cardiovascular-surgical-patients-in-the-icu-a-prospective-pilot-diagnostic-accuracy-study"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,31]]},"references-count":28,"URL":"https:\/\/doi.org\/10.7759\/cureus.100502","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12,31]]}}}