{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,3]],"date-time":"2026-01-03T14:25:06Z","timestamp":1767450306981,"version":"3.48.0"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,3]]},"DOI":"10.7759\/cureus.100682","type":"journal-article","created":{"date-parts":[[2026,1,3]],"date-time":"2026-01-03T14:21:36Z","timestamp":1767450096000},"source":"Crossref","is-referenced-by-count":0,"title":["Functional and Cognitive Decline in an Older Adult With Severe Hyponatremia and Undiagnosed Hypothyroidism: A Geriatric Perspective"],"prefix":"10.7759","author":[{"given":"Parul","family":"Bhutani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhagyashree","family":"Tanwar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikhil","family":"Choudhary","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minakshi","family":"Dhar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1177\/20420188231180983","article-title":"Is there a causal relationship between hypothyroidism and hyponatremia?","volume":"14","author":"Chen J","year":"2023","unstructured":"Chen J. Is there a causal relationship between hypothyroidism and hyponatremia?. Ther Adv Endocrinol Metab. 2023, 14:20420188231180983. 10.1177\/20420188231180983","journal-title":"Ther Adv Endocrinol Metab"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.31729\/jnma.7471","article-title":"Hypothyroidism induced hyponatremia: a case report","volume":"60","author":"Maharjan G","year":"2022","unstructured":"Maharjan G, Yadav MK, Khati N, Yadav SK, Shrestha TR. Hypothyroidism induced hyponatremia: a case report. J Nepal Med Assoc. 2022, 60:815-6. 10.31729\/jnma.7471","journal-title":"J Nepal Med Assoc"},{"key":"ref3","doi-asserted-by":"crossref","DOI":"10.1016\/S0300-2977(01)00081-X","article-title":"Hyponatremia due to hypothyroidism: a pure renal mechanism","volume":"58","author":"Schmitz PH","year":"2001","unstructured":"Schmitz PH, De Meijer PH, Meinders A. Hyponatremia due to hypothyroidism: a pure renal mechanism. Netherlands Journal of Medicine. 2001, 58:143-9.","journal-title":"Netherlands Journal of Medicine"},{"key":"ref4","article-title":"An enigma of hypothyroidism and hyponatremia coexistence: A nationwide population-based retrospective study","volume":"23","author":"Chu CH","year":"2023","unstructured":"Chu CH, Chien WC, Liu CC, et al.. An enigma of hypothyroidism and hyponatremia coexistence: A nationwide population-based retrospective study. BMC Public Health. 2023, 23:1889.","journal-title":"BMC Public Health"},{"key":"ref5","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0205687","article-title":"Prevalence of hypothyroidism in patients with hyponatremia: a retrospective cross-sectional study","volume":"13","author":"Nagata T","year":"2018","unstructured":"Nagata T, Nakajima S, Fujiya A, Sobajima H, Yamaguchi M. Prevalence of hypothyroidism in patients with hyponatremia: a retrospective cross-sectional study. PLoS One. 2018, 13:e0205687..","journal-title":"PLoS One"},{"key":"ref6","article-title":"Hypothyroidism in older adults","author":"Kim MI","year":"2020","unstructured":"Kim MI, Bertot BE. Hypothyroidism in older adults. Endotext.  Feingold KR, Adler RA, Ahmed SF, et al. (ed): MDText.com, Inc, South Dartmouth, MA, USA; 2020."},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2019.00177","article-title":"Overt and subclinical hypothyroidism in the elderly: when to treat?","volume":"10","author":"Calsolaro V","year":"2019","unstructured":"Calsolaro V, Niccolai F, Pasqualetti G, et al.. Overt and subclinical hypothyroidism in the elderly: when to treat?. J Endocr Soc. 2019, 10:177. 10.3389\/fendo.2019.00177","journal-title":"J Endocr Soc"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1038\/srep38912","article-title":"Gait patterns associated with thyroid function: the Rotterdam Study","volume":"6","author":"Bano A","year":"2016","unstructured":"Bano A, Chaker L, Darweesh SK, et al.. Gait patterns associated with thyroid function: the Rotterdam Study. Sci Rep. 2016, 6:38912. 10.1038\/srep38912","journal-title":"Sci Rep"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2015.00150","article-title":"Subclinical hypothyroidism and cognitive function in people over 60 years: a systematic review and meta-analysis","volume":"7","author":"Akintola AA","year":"2015","unstructured":"Akintola AA, Jansen SW, Van Bodegom D, Van Der Grond J, Westendorp RG, De Craen AJ, Van Heemst D. Subclinical hypothyroidism and cognitive function in people over 60 years: a systematic review and meta-analysis. Front Aging Neurosci. 2015, 7:150. 10.3389\/fnagi.2015.00150","journal-title":"Front Aging Neurosci"},{"key":"ref10","doi-asserted-by":"crossref","DOI":"10.1016\/j.eprac.2024.07.013","article-title":"Thyroid function and cognitive decline: a narrative review","volume":"30","author":"Sinha SH","year":"2024","unstructured":"Sinha SH, Zietlow K, Papaleontiou M. Thyroid function and cognitive decline: a narrative review. Endocr Pract. 2024, 30:1113-8.","journal-title":"Endocr Pract"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1963.03060120024016","article-title":"Studies of illness in the aged. The index of ADL: a standardized measure of biological and psychosocial function","volume":"185","author":"KA S","year":"1963","unstructured":"KA S, FO AB, MO RW, JA BA, JA MW. Studies of illness in the aged. The index of ADL: a standardized measure of biological and psychosocial function. J Am Med Assoc. 1963, 185:914-9. 10.1001\/jama.1963.03060120024016","journal-title":"J Am Med Assoc"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.050051","article-title":"A global clinical measure of fitness and frailty in elderly people","volume":"173","author":"Rockwood K","year":"2005","unstructured":"Rockwood K, Song X, MacKnight C, Bergman H, Hogan DB, McDowell I, Mitnitski A. A global clinical measure of fitness and frailty in elderly people. Can Med Assoc J. 2005, 173:489-95. 10.1503\/cmaj.050051","journal-title":"Can Med Assoc J"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-113-12-941","article-title":"Clarifying confusion: the confusion assessment method: a new method for detection of delirium","volume":"113","author":"Inouye SK","year":"1990","unstructured":"Inouye SK, van Dyck CH, Alessi CA, Balkin S, Siegal AP, Horwitz RI. Clarifying confusion: the confusion assessment method: a new method for detection of delirium. Ann Intern Med. 1990, 113:941-8. 10.7326\/0003-4819-113-12-941","journal-title":"Ann Intern Med"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/56.6.m366","article-title":"Screening for undernutrition in geriatric practice: developing the short-form mini-nutritional assessment (MNA-SF)","volume":"56","author":"Rubenstein LZ","year":"2001","unstructured":"Rubenstein LZ, Harker JO, Salv\u00e0 A, Guigoz Y, Vellas B. Screening for undernutrition in geriatric practice: developing the short-form mini-nutritional assessment (MNA-SF). J Gerontol A Biol Sci Med Sci. 2001, 56:M366-72. 10.1093\/gerona\/56.6.m366","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1002\/gps.930100505","article-title":"A Hindi version of the MMSE: the development of a cognitive screening instrument for the illiterate elderly in India","volume":"10","author":"Ganguli M","year":"1995","unstructured":"Ganguli M, Ratcliff G, Chandra V, et al.. A Hindi version of the MMSE: the development of a cognitive screening instrument for the illiterate elderly in India. Int J Geriatr Psychiatry. 1995, 10:367-77. 10.1002\/gps.930100505","journal-title":"Int J Geriatr Psychiatry"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(82)90033-4","article-title":"Development and validation of a geriatric depression screening scale: a preliminary report","volume":"17","author":"Yesavage JA","year":"1983","unstructured":"Yesavage JA, Brink TL, Rose TL, et al.. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res. 1983, 17:37-49. 10.1016\/0022-3956(82)90033-4","journal-title":"J Psychiatr Res"},{"key":"ref17","doi-asserted-by":"crossref","DOI":"10.1111\/j.1532-5415.1991.tb01616.x","article-title":"The timed \"Up & Go\": a test of basic functional mobility for frail elderly persons","volume":"39","author":"Podsiadlo D","year":"1991","unstructured":"Podsiadlo D, Richardson S. The timed \"Up &amp; Go\": a test of basic functional mobility for frail elderly persons. J Am Geriatr Soc. 1991, 39:142-8.","journal-title":"J Am Geriatr Soc"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afr051","article-title":"A review of the measurement of grip strength in clinical and epidemiological studies: towards a standardised approach","volume":"40","author":"Roberts HC","year":"2011","unstructured":"Roberts HC, Denison HJ, Martin HJ, Patel HP, Syddall H, Cooper C, Sayer AA. A review of the measurement of grip strength in clinical and epidemiological studies: towards a standardised approach. Age Ageing. 2011, 40:423-9. 10.1093\/ageing\/afr051","journal-title":"Age Ageing"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/449123-functional-and-cognitive-decline-in-an-older-adult-with-severe-hyponatremia-and-undiagnosed-hypothyroidism-a-geriatric-perspective","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,3]],"date-time":"2026-01-03T14:21:38Z","timestamp":1767450098000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/449123-functional-and-cognitive-decline-in-an-older-adult-with-severe-hyponatremia-and-undiagnosed-hypothyroidism-a-geriatric-perspective"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,3]]},"references-count":18,"URL":"https:\/\/doi.org\/10.7759\/cureus.100682","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1,3]]}}}