{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T01:08:59Z","timestamp":1774314539392,"version":"3.50.1"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,5]]},"DOI":"10.7759\/cureus.100860","type":"journal-article","created":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T00:27:51Z","timestamp":1767659271000},"source":"Crossref","is-referenced-by-count":1,"title":["Beneath the Cure Lies the Risk: Carbimazole-Induced Angioedema in Graves' Disease"],"prefix":"10.7759","author":[{"given":"Judat","family":"Tasawoor","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariya","family":"Manzoor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abir","family":"Aijaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zagham","family":"Hammad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hadiya","family":"Chisti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayesha","family":"Babar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manzoor","family":"Wani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdul","family":"Bhat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","article-title":"Methimazole","author":"Awosika AO","year":"2023","unstructured":"Awosika AO. Methimazole. StatPearls. StatPearls Publishing, Treasure Island, FL; 2023."},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2013-2569","article-title":"Analysis of 754 cases of antithyroid drug-induced agranulocytosis over 30 years in Japan","volume":"98","author":"Nakamura H","year":"2013","unstructured":"Nakamura H, Miyauchi A, Miyawaki N, Imagawa J. Analysis of 754 cases of antithyroid drug-induced agranulocytosis over 30 years in Japan. J Clin Endocrinol Metab. 2013, 98:4776-83. 10.1210\/jc.2013-2569","journal-title":"J Clin Endocrinol Metab"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2019.00789","article-title":"Granulocyte-colony-stimulating factor effectively shortens recovery duration in anti-thyroid-drug-induced agranulocytosis: a systematic review and meta-analysis","volume":"10","author":"Wang Y","year":"2019","unstructured":"Wang Y, Li X, Yang Q, et al.. Granulocyte-colony-stimulating factor effectively shortens recovery duration in anti-thyroid-drug-induced agranulocytosis: a systematic review and meta-analysis. Front Endocrinol (Lausanne). 2019, 10:789. 10.3389\/fendo.2019.00789","journal-title":"Front Endocrinol (Lausanne)"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.4463","article-title":"Multifocal osteomyelitis localization after pyomyositis in children: importance of timely response","volume":"11","author":"Angelis S","year":"2019","unstructured":"Angelis S, Trellopoulos A, Kondylis AK, et al.. Multifocal osteomyelitis localization after pyomyositis in children: importance of timely response. Cureus. 2019, 11:e4463. 10.7759\/cureus.4463","journal-title":"Cureus"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.4158\/EP-2019-0221","article-title":"Side effects of PTU and MMI in the treatment of hyperthyroidism: a systematic review and meta-analysis","volume":"26","author":"Yu W","year":"2020","unstructured":"Yu W, Wu N, Li L, Wang J, OuYang H, Shen H. Side effects of PTU and MMI in the treatment of hyperthyroidism: a systematic review and meta-analysis. Endocr Pract. 2020, 26:207-17. 10.4158\/EP-2019-0221","journal-title":"Endocr Pract"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1159\/000342920","article-title":"Side effects of anti-thyroid drugs and their impact on the choice of treatment for thyrotoxicosis in pregnancy","volume":"1","author":"Taylor PN","year":"2012","unstructured":"Taylor PN, Vaidya B. Side effects of anti-thyroid drugs and their impact on the choice of treatment for thyrotoxicosis in pregnancy. Eur Thyroid J. 2012, 1:176-85. 10.1159\/000342920","journal-title":"Eur Thyroid J"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-98-1-26","article-title":"Agranulocytosis associated with antithyroid drugs. Effects of patient age and drug dose","volume":"98","author":"Cooper DS","year":"1983","unstructured":"Cooper DS, Goldminz D, Levin AA, Ladenson PW, Daniels GH, Molitch ME, Ridgway EC. Agranulocytosis associated with antithyroid drugs. Effects of patient age and drug dose. Ann Intern Med. 1983, 98:26-9. 10.7326\/0003-4819-98-1-26","journal-title":"Ann Intern Med"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12206556","article-title":"Therapeutic management and long-term outcome of hyperthyroidism in patients with antithyroid-induced agranulocytosis: a retrospective, multicenter study","volume":"12","author":"Garc\u00eda G\u00f3mez C","year":"2023","unstructured":"Garc\u00eda G\u00f3mez C, Navarro E, Alc\u00e1zar V, et al.. Therapeutic management and long-term outcome of hyperthyroidism in patients with antithyroid-induced agranulocytosis: a retrospective, multicenter study. J Clin Med. 2023, 12:6556. 10.3390\/jcm12206556","journal-title":"J Clin Med"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2016.0229","article-title":"2016 American Thyroid Association Guidelines for Diagnosis and Management of Hyperthyroidism and Other Causes of Thyrotoxicosis","volume":"26","author":"Ross DS","year":"2016","unstructured":"Ross DS, Burch HB, Cooper DS, et al.. 2016 American Thyroid Association Guidelines for Diagnosis and Management of Hyperthyroidism and Other Causes of Thyrotoxicosis. Thyroid. 2016, 26:1343-1421. 10.1089\/thy.2016.0229","journal-title":"Thyroid"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10071-23224","article-title":"Carbimazole-induced anaphylactic shock: a case report","volume":"23","author":"Keyal NK","year":"2019","unstructured":"Keyal NK, Thapa S, Yadav MK. Carbimazole-induced anaphylactic shock: a case report. Indian J Crit Care Med. 2019, 23:380-1. 10.5005\/jp-journals-10071-23224","journal-title":"Indian J Crit Care Med"},{"key":"ref11","doi-asserted-by":"crossref","DOI":"10.1210\/jendso\/bvab048.1870","article-title":"A rare case of anaphylaxis to methimazole in a patient with Graves\u2019 disease","volume":"5","author":"Garg D","year":"2021","unstructured":"Garg D, Garcia GA, Praw SS. A rare case of anaphylaxis to methimazole in a patient with Graves\u2019 disease. J Endocr Soc. 2021, 5:A915-6.","journal-title":"J Endocr Soc"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/435959-beneath-the-cure-lies-the-risk-carbimazole-induced-angioedema-in-graves-disease","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T00:27:52Z","timestamp":1767659272000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/435959-beneath-the-cure-lies-the-risk-carbimazole-induced-angioedema-in-graves-disease"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,5]]},"references-count":11,"URL":"https:\/\/doi.org\/10.7759\/cureus.100860","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1,5]]}}}