{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T04:38:07Z","timestamp":1767674287650,"version":"3.48.0"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,5]]},"DOI":"10.7759\/cureus.100869","type":"journal-article","created":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T04:35:12Z","timestamp":1767674112000},"source":"Crossref","is-referenced-by-count":0,"title":["The Impact of Maternal Metabolic Syndrome on Gross Placental Structure in Term Pregnancies: A Comparative Study"],"prefix":"10.7759","author":[{"given":"Mukund","family":"Vatsa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rashmi","family":"Malhotra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mukesh","family":"Singla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Om","family":"Kumari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shailza","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bharti","family":"Jakhar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. Ankush","family":"Patil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00029.2015","article-title":"Placental origins of chronic disease","volume":"96","author":"Burton GJ","year":"2016","unstructured":"Burton GJ, Fowden AL, Thornburg KL. Placental origins of chronic disease. Physiol Rev. 2016, 96:1509-65. 10.1152\/physrev.00029.2015","journal-title":"Physiol Rev"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2022.03.039","article-title":"Human placental development and function","volume":"131","author":"Cindrova-Davies T","year":"2022","unstructured":"Cindrova-Davies T, Sferruzzi-Perri AN. Human placental development and function. Semin Cell Dev Biol. 2022, 131:66-77. 10.1016\/j.semcdb.2022.03.039","journal-title":"Semin Cell Dev Biol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2003.11.003","article-title":"Prevalence of metabolic syndrome in an Indian urban population","volume":"97","author":"Gupta R","year":"2004","unstructured":"Gupta R, Deedwania PC, Gupta A, Rastogi S, Panwar RB, Kothari K. Prevalence of metabolic syndrome in an Indian urban population. Int J Cardiol. 2004, 97:257-61. 10.1016\/j.ijcard.2003.11.003","journal-title":"Int J Cardiol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.mjafi.2019.12.001","article-title":"Metabolic syndrome: the Indian public health perspective","volume":"76","author":"Bhalwar R","year":"2020","unstructured":"Bhalwar R. Metabolic syndrome: the Indian public health perspective. Med J Armed Forces India. 2020, 76:8-16. 10.1016\/j.mjafi.2019.12.001","journal-title":"Med J Armed Forces India"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.21522\/TIJPH.2013.12.04.Art029","article-title":"Metabolic syndrome in pregnancy and its complications in obstetrics and newborn","volume":"12","author":"Smitha S","year":"2024","unstructured":"Smitha S, Sornam MS, Preethi B, Meena TS. Metabolic syndrome in pregnancy and its complications in obstetrics and newborn. Texila Int J Public Health. 2024, 12:029. 10.21522\/TIJPH.2013.12.04.Art029","journal-title":"Texila Int J Public Health"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00002.2020","article-title":"Developmental origins of metabolic diseases","volume":"101","author":"Hoffman DJ","year":"2021","unstructured":"Hoffman DJ, Powell TL, Barrett ES, Hardy DB. Developmental origins of metabolic diseases. Physiol Rev. 2021, 101:739-95. 10.1152\/physrev.00002.2020","journal-title":"Physiol Rev"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO;2-S","article-title":"Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus. Provisional report of a WHO consultation","volume":"15","author":"Alberti KG","year":"1998","unstructured":"Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus. Provisional report of a WHO consultation. Diabet Med. 1998, 15:539-53. 10.1002\/(SICI)1096-9136(199807)15:7&lt;539::AID-DIA668&gt;3.0.CO;2-S","journal-title":"Diabet Med"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.993619","article-title":"Endocrine and metabolic interactions in healthy pregnancies and hyperinsulinemic pregnancies affected by polycystic ovary syndrome, diabetes and obesity","volume":"13","author":"Neven AC","year":"2022","unstructured":"Neven AC, Mousa A, Boyle JA, Teede HJ. Endocrine and metabolic interactions in healthy pregnancies and hyperinsulinemic pregnancies affected by polycystic ovary syndrome, diabetes and obesity. Front Endocrinol (Lausanne). 2022, 13:993619. 10.3389\/fendo.2022.993619","journal-title":"Front Endocrinol (Lausanne)"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67402-8","article-title":"The metabolic syndrome\u2014a new worldwide definition","volume":"24","author":"Alberti KG","year":"2005","unstructured":"Alberti KG, Zimmet P, Shaw J. The metabolic syndrome\u2014a new worldwide definition. Lancet. 2005, 24:1059-62. 10.1016\/S0140-6736(05)67402-8","journal-title":"Lancet"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2007.09.003","article-title":"Placental pathology: a systematic approach with clinical correlations","volume":"29","author":"Redline RW","year":"2008","unstructured":"Redline RW. Placental pathology: a systematic approach with clinical correlations. Placenta. 2008, 29:S86-91. 10.1016\/j.placenta.2007.09.003","journal-title":"Placenta"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.01.012","article-title":"Placental vascular lesion differences in pregnancy-induced hypertension and normotensive fetal growth restriction","volume":"202","author":"Kovo M","year":"2010","unstructured":"Kovo M, Schreiber L, Ben-Haroush A, Wand S, Golan A, Bar J. Placental vascular lesion differences in pregnancy-induced hypertension and normotensive fetal growth restriction. Am J Obstet Gynecol. 2010, 202:561.e1-5. 10.1016\/j.ajog.2010.01.012","journal-title":"Am J Obstet Gynecol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.62871","article-title":"Morphological, morphometric, and histological evaluation of the placenta in cases of intrauterine fetal death","volume":"16","author":"Paiker M","year":"2024","unstructured":"Paiker M, Khan K, Mishra D, et al.. Morphological, morphometric, and histological evaluation of the placenta in cases of intrauterine fetal death. Cureus. 2024, 16:e62871. 10.7759\/cureus.62871","journal-title":"Cureus"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0239630","article-title":"Umbilical cord characteristics and their association with adverse pregnancy outcomes: a systematic review and meta-analysis","volume":"15","author":"Hayes DJ","year":"2020","unstructured":"Hayes DJ, Warland J, Parast MM, et al.. Umbilical cord characteristics and their association with adverse pregnancy outcomes: a systematic review and meta-analysis. PLoS One. 2020, 15:e0239630. 10.1371\/journal.pone.0239630","journal-title":"PLoS One"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2010.09.005","article-title":"Placental surface shape, function, and effects of maternal and fetal vascular pathology","volume":"31","author":"Salafia CM","year":"2010","unstructured":"Salafia CM, Yampolsky M, Misra DP, Shlakhter O, Haas D, Eucker B, Thorp J. Placental surface shape, function, and effects of maternal and fetal vascular pathology. Placenta. 2010, 31:958-62. 10.1016\/j.placenta.2010.09.005","journal-title":"Placenta"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2008.06.005","article-title":"Modeling the variability of shapes of a human placenta","volume":"29","author":"Yampolsky M","year":"2008","unstructured":"Yampolsky M, Salafia CM, Shlakhter O, Haas D, Eucker B, Thorp J. Modeling the variability of shapes of a human placenta. Placenta. 2008, 29:790-7. 10.1016\/j.placenta.2008.06.005","journal-title":"Placenta"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2007.05.002","article-title":"Regulation of placental nutrient transport--a review","volume":"28","author":"Jones HN","year":"2007","unstructured":"Jones HN, Powell TL, Jansson T. Regulation of placental nutrient transport--a review. Placenta. 2007, 28:763-74. 10.1016\/j.placenta.2007.05.002","journal-title":"Placenta"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2004.04.011","article-title":"Morphometric evidence that villous development and fetoplacental angiogenesis are compromised by intrauterine growth restriction but not by pre-eclampsia","volume":"25","author":"Mayhew TM","year":"2004","unstructured":"Mayhew TM, Wijesekara J, Baker PN, Ong SS. Morphometric evidence that villous development and fetoplacental angiogenesis are compromised by intrauterine growth restriction but not by pre-eclampsia. Placenta. 2004, 25:829-33. 10.1016\/j.placenta.2004.04.011","journal-title":"Placenta"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0194814","article-title":"Extreme umbilical cord lengths, cord knot and entanglement: risk factors and risk of adverse outcomes, a population-based study","volume":"13","author":"Linde LE","year":"2018","unstructured":"Linde LE, Rasmussen S, Kessler J, Ebbing C. Extreme umbilical cord lengths, cord knot and entanglement: risk factors and risk of adverse outcomes, a population-based study. PLoS One. 2018, 13:e0194814. 10.1371\/journal.pone.0194814","journal-title":"PLoS One"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2014.11.021","article-title":"A systematic review of placental pathology in maternal diabetes mellitus","volume":"36","author":"Huynh J","year":"2015","unstructured":"Huynh J, Dawson D, Roberts D, Bentley-Lewis R. A systematic review of placental pathology in maternal diabetes mellitus. Placenta. 2015, 36:101-14. 10.1016\/j.placenta.2014.11.021","journal-title":"Placenta"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/S0143-4004(03)00128-0","article-title":"Placental pathology in women with type 1 diabetes and in a control group with normal and large-for-gestational-age infants","volume":"24","author":"Evers IM","year":"2003","unstructured":"Evers IM, Nikkels PG, Sikkema JM, Visser GH. Placental pathology in women with type 1 diabetes and in a control group with normal and large-for-gestational-age infants. Placenta. 2003, 24:819-25. 10.1016\/S0143-4004(03)00128-0","journal-title":"Placenta"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0040296","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"4","author":"von Elm E","year":"2007","unstructured":"von Elm E, Altman DG, Egger M, Pocock SJ, G\u00f8tzsche PC, Vandenbroucke JP. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. PLoS Med. 2007, 4:e296. 10.1371\/journal.pmed.0040296","journal-title":"PLoS Med"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/449805-the-impact-of-maternal-metabolic-syndrome-on-gross-placental-structure-in-term-pregnancies-a-comparative-study","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T04:35:14Z","timestamp":1767674114000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/449805-the-impact-of-maternal-metabolic-syndrome-on-gross-placental-structure-in-term-pregnancies-a-comparative-study"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,5]]},"references-count":21,"URL":"https:\/\/doi.org\/10.7759\/cureus.100869","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1,5]]}}}