{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T17:55:04Z","timestamp":1767722104171,"version":"3.48.0"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,6]]},"DOI":"10.7759\/cureus.100936","type":"journal-article","created":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T17:54:01Z","timestamp":1767722041000},"source":"Crossref","is-referenced-by-count":0,"title":["A Case of Facial Nerve Palsy As the Initial Presentation of Early Neurosyphilis: A Diagnostic Challenge"],"prefix":"10.7759","author":[{"given":"Tamara","family":"Kewan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaron","family":"River","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2023.1340321","article-title":"Neurosyphilis: insights into its pathogenesis, susceptibility, diagnosis, treatment, and prevention","volume":"14","author":"Wu S","year":"2024","unstructured":"Wu S, Ye F, Wang Y, Li D. Neurosyphilis: insights into its pathogenesis, susceptibility, diagnosis, treatment, and prevention. Front Neurol. 2024, 14:1340321. 10.3389\/fneur.2023.1340321","journal-title":"Front Neurol"},{"key":"ref2","article-title":"Neurosyphilis","author":"Ha T","year":"2025","unstructured":"Ha T, Tadi P, Leslie SW, Dubensky L. Neurosyphilis. StatPearls Publishing, Treasure Island, FL; 2025."},{"key":"ref3","article-title":"Sexually Transmitted Infections Surveillance 2022","author":"Centers for Disease Control and Prevention","year":"2023","unstructured":"Centers for Disease Control and Prevention. Sexually Transmitted Infections Surveillance 2022. Department of Health and Human Services, Atlanta, US; 2023."},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1272\/jnms.82.254","article-title":"Neurosyphilis mimicking Ramsay Hunt syndrome","volume":"82","author":"Maeda T","year":"2015","unstructured":"Maeda T, Yoshizawa S, Hirayama T, Saga T, Tateda K, Urita Y. Neurosyphilis mimicking Ramsay Hunt syndrome. J Nippon Med Sch. 2015, 82:254-256. 10.1272\/jnms.82.254","journal-title":"J Nippon Med Sch"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1017\/cem.2015.83","article-title":"Bilateral facial nerve palsy as the sole initial symptom of syphilis: a case report","volume":"17","author":"Ting CH","year":"2015","unstructured":"Ting CH, Wang CW, Lee JT, Peng GS, Yang FC. Bilateral facial nerve palsy as the sole initial symptom of syphilis: a case report. CJEM. 2015, 17:576-581. 10.1017\/cem.2015.83","journal-title":"CJEM"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-017-1297-0","article-title":"Early neurosyphilis presenting with facial palsy and an oral ulcer in a patient who is human immunodeficiency virus positive: a case report","volume":"11","author":"Njiru E","year":"2017","unstructured":"Njiru E, Abdulkadir J, Kamuren Z, Kigen G. Early neurosyphilis presenting with facial palsy and an oral ulcer in a patient who is human immunodeficiency virus positive: a case report. J Med Case Rep. 2017, 11:134. 10.1186\/s13256-017-1297-0","journal-title":"J Med Case Rep"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-005-0927-4","article-title":"HIV-associated neurosyphilis mimicking acoustic neurinoma","volume":"253","author":"B\u00f6sel J","year":"2006","unstructured":"B\u00f6sel J, Klingebiel R, Schielke E. HIV-associated neurosyphilis mimicking acoustic neurinoma. J Neurol. 2006, 253:250-252. 10.1007\/s00415-005-0927-4","journal-title":"J Neurol"},{"key":"ref8","article-title":"Neurosyphilis as a cause of facial and vestibulocochlear nerve dysfunction: MR imaging features","volume":"21","author":"Smith MM","year":"2000","unstructured":"Smith MM, Anderson JC. Neurosyphilis as a cause of facial and vestibulocochlear nerve dysfunction: MR imaging features. AJNR Am J Neuroradiol. 2000, 21:1673-1675.","journal-title":"AJNR Am J Neuroradiol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2014-206988","article-title":"Neurosyphilis presenting with a stroke-like syndrome","volume":"2015","author":"Abkur TM","year":"2015","unstructured":"Abkur TM, Ahmed GS, Alfaki NO, O'Connor M. Neurosyphilis presenting with a stroke-like syndrome. BMJ Case Rep. 2015, 2015:10.1136\/bcr-2014-206988","journal-title":"BMJ Case Rep"},{"key":"ref10","unstructured":"Syphilis 2024. Updated Guideline. (2024). https:\/\/www.bashh.org\/resources\/25\/updated_guideline_syphilis_2024\/."},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e32830184df","article-title":"Neurosyphilis in a clinical cohort of HIV-1-infected patients","volume":"22","author":"Ghanem KG","year":"2008","unstructured":"Ghanem KG, Moore RD, Rompalo AM, Erbelding EJ, Zenilman JM, Gebo KA. Neurosyphilis in a clinical cohort of HIV-1-infected patients. AIDS. 2008, 22:1145-1151. 10.1097\/QAD.0b013e32830184df","journal-title":"AIDS"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1906228","article-title":"Neurosyphilis","volume":"381","author":"Ropper AH","year":"2019","unstructured":"Ropper AH. Neurosyphilis. N Engl J Med. 2019, 381:1358-1363. 10.1056\/NEJMra1906228","journal-title":"N Engl J Med"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1055\/s-0042-1744523","article-title":"Magnetic resonance imaging in otosyphilis: a rare manifestation of neurosyphilis","volume":"32","author":"Chandrasekharan R","year":"2022","unstructured":"Chandrasekharan R, Kulkarni C, Pullara SK, Moorthy S. Magnetic resonance imaging in otosyphilis: a rare manifestation of neurosyphilis. Indian J Radiol Imaging. 2022, 32:278-284. 10.1055\/s-0042-1744523","journal-title":"Indian J Radiol Imaging"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.892292","article-title":"Acute cranial neuropathies heralding neurosyphilis in human immunodeficiency virus-infected patient","volume":"15","author":"Alqahtani S","year":"2014","unstructured":"Alqahtani S. Acute cranial neuropathies heralding neurosyphilis in human immunodeficiency virus-infected patient. Am J Case Rep. 2014, 15:411-415. 10.12659\/AJCR.892292","journal-title":"Am J Case Rep"},{"key":"ref15","article-title":"Neurosyphilis in HIV-positive and HIV-negative patients: neuroimaging findings","volume":"16","author":"15] Brightbill TC","year":"1995","unstructured":"15] Brightbill TC, Ihmeidan IH, Post MJ, et al.. Neurosyphilis in HIV-positive and HIV-negative patients: neuroimaging findings. AJNR Am J Neuroradiol. 1995, 16:703-711.","journal-title":"AJNR Am J Neuroradiol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1177\/0194599813505967","article-title":"Clinical practice guideline: Bell's palsy","volume":"149","author":"Baugh RF","year":"2013","unstructured":"Baugh RF, Basura GJ, Ishii LE, et al.. Clinical practice guideline: Bell's palsy. Otolaryngol Head Neck Surg. 2013, 149:S1-27. 10.1177\/0194599813505967","journal-title":"Otolaryngol Head Neck Surg"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.16-0434","article-title":"The Jarisch-Herxheimer reaction after antibiotic treatment of spirochetal infections: a review of recent cases and our understanding of pathogenesis","volume":"96","author":"Butler T","year":"2017","unstructured":"Butler T. The Jarisch-Herxheimer reaction after antibiotic treatment of spirochetal infections: a review of recent cases and our understanding of pathogenesis. Am J Trop Med Hyg. 2017, 96:46-52. 10.4269\/ajtmh.16-0434","journal-title":"Am J Trop Med Hyg"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/442309-a-case-of-facial-nerve-palsy-as-the-initial-presentation-of-early-neurosyphilis-a-diagnostic-challenge","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T17:54:02Z","timestamp":1767722042000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/442309-a-case-of-facial-nerve-palsy-as-the-initial-presentation-of-early-neurosyphilis-a-diagnostic-challenge"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,6]]},"references-count":17,"URL":"https:\/\/doi.org\/10.7759\/cureus.100936","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1,6]]}}}