{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T05:30:11Z","timestamp":1767936611976,"version":"3.49.0"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,8]]},"DOI":"10.7759\/cureus.101075","type":"journal-article","created":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T12:44:51Z","timestamp":1767876291000},"source":"Crossref","is-referenced-by-count":0,"title":["Quantitative Magnetic Resonance Imaging Biomarkers in the Evaluation of Disease Activity in Thyroid Eye Disease: A Retrospective Study"],"prefix":"10.7759","author":[{"given":"Duncan","family":"Marston","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Grech","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea Noah","family":"Paris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Galdes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isaac","family":"Bertuello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Palmier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0905750","article-title":"Graves' ophthalmopathy","volume":"362","author":"Bahn RS","year":"2010","unstructured":"Bahn RS. Graves' ophthalmopathy. N Engl J Med. 2010, 362:726-38. 10.1056\/NEJMra0905750","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-21-0479","article-title":"The 2021 European Group on Graves' orbitopathy (EUGOGO) clinical practice guidelines for the medical management of Graves' orbitopathy","volume":"185","author":"Bartalena L","year":"2021","unstructured":"Bartalena L, Kahaly GJ, Baldeschi L, et al.. The 2021 European Group on Graves' orbitopathy (EUGOGO) clinical practice guidelines for the medical management of Graves' orbitopathy. Eur J Endocrinol. 2021, 185:G43-67. 10.1530\/EJE-21-0479","journal-title":"Eur J Endocrinol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1510030","article-title":"Graves' disease","volume":"375","author":"Smith TJ","year":"2016","unstructured":"Smith TJ, Heged\u00fcs L. Graves' disease. N Engl J Med. 2016, 375:1552-65. 10.1056\/NEJMra1510030","journal-title":"N Engl J Med"},{"key":"ref4","article-title":"Graves\u2019 Orbitopathy: A Multidisciplinary Approach","author":"Wiersinga WM","year":"2021","unstructured":"Wiersinga WM, Kahaly GJ. Graves\u2019 Orbitopathy: A Multidisciplinary Approach. Wiersinga WM, Kahaly GJ (ed): Karger, Basel; 2021."},{"key":"ref5","article-title":"Development and course of exophthalmos and ophthalmoplegia in Graves' disease with special reference to the effect of thyroidectomy","volume":"5","author":"RU FF","year":"1945","unstructured":"RU FF, WI CW. Development and course of exophthalmos and ophthalmoplegia in Graves' disease with special reference to the effect of thyroidectomy. Clin Sci. 1945, 5:177-94.","journal-title":"Clin Sci"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2011.11.007","article-title":"Evaluating Graves' orbitopathy","volume":"26","author":"Dolman PJ","year":"2012","unstructured":"Dolman PJ. Evaluating Graves' orbitopathy. Best Pract Res Clin Endocrinol Metab. 2012, 26:229-48. 10.1016\/j.beem.2011.11.007","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1910434","article-title":"Teprotumumab for the treatment of active thyroid eye disease","volume":"382","author":"Douglas RS","year":"2020","unstructured":"Douglas RS, Kahaly GJ, Patel A, et al.. Teprotumumab for the treatment of active thyroid eye disease. N Engl J Med. 2020, 382:341-52. 10.1056\/NEJMoa1910434","journal-title":"N Engl J Med"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.73.8.639","article-title":"Clinical criteria for the assessment of disease activity in Graves' ophthalmopathy: a novel approach","volume":"73","author":"Mourits MP","year":"1989","unstructured":"Mourits MP, Koornneef L, Wiersinga WM, Prummel MF, Berghout A, van der Gaag R. Clinical criteria for the assessment of disease activity in Graves' ophthalmopathy: a novel approach. Br J Ophthalmol. 1989, 73:639-44. 10.1136\/bjo.73.8.639","journal-title":"Br J Ophthalmol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-014-3103-3","article-title":"Magnetic resonance imaging with diffusion-weighted imaging in the evaluation of thyroid-associated orbitopathy: getting below the tip of the iceberg","volume":"24","author":"Politi LS","year":"2014","unstructured":"Politi LS, Godi C, Cammarata G, et al.. Magnetic resonance imaging with diffusion-weighted imaging in the evaluation of thyroid-associated orbitopathy: getting below the tip of the iceberg. Eur Radiol. 2014, 24:1118-26. 10.1007\/s00330-014-3103-3","journal-title":"Eur Radiol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s10384-014-0365-x","article-title":"Use of MRI signal intensity of extraocular muscles to evaluate methylprednisolone pulse therapy in thyroid-associated ophthalmopathy","volume":"59","author":"Higashiyama T","year":"2015","unstructured":"Higashiyama T, Nishida Y, Morino K, Ugi S, Nishio Y, Maegawa H, Ohji M. Use of MRI signal intensity of extraocular muscles to evaluate methylprednisolone pulse therapy in thyroid-associated ophthalmopathy. Jpn J Ophthalmol. 2015, 59:124-30. 10.1007\/s10384-014-0365-x","journal-title":"Jpn J Ophthalmol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2010.08.042","article-title":"Correlation of retrobulbar volume change with resected orbital fat volume and proptosis reduction after fatty decompression for Graves ophthalmopathy","volume":"151","author":"Liao SL","year":"2011","unstructured":"Liao SL, Huang SW. Correlation of retrobulbar volume change with resected orbital fat volume and proptosis reduction after fatty decompression for Graves ophthalmopathy. Am J Ophthalmol. 2011, 151:465-9.e1. 10.1016\/j.ajo.2010.08.042","journal-title":"Am J Ophthalmol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1080\/17469899.2017.1276444","article-title":"Dysthyroid optic neuropathy: update on pathogenesis, diagnosis, and management","volume":"12","author":"Blandford AD","year":"2017","unstructured":"Blandford AD, Zhang D, Chundury RV, Perry JD. Dysthyroid optic neuropathy: update on pathogenesis, diagnosis, and management. Expert Rev Ophthalmol. 2017, 12:111-21. 10.1080\/17469899.2017.1276444","journal-title":"Expert Rev Ophthalmol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.5114\/pjr.2019.84096","article-title":"Assessment of lacrimal glands in thyroid eye disease with diffusion-weighted magnetic resonance imaging","volume":"84","author":"Razek AA","year":"2019","unstructured":"Razek AA, El-Hadidy EM, Moawad ME, El-Metwaly N, El-Said AA. Assessment of lacrimal glands in thyroid eye disease with diffusion-weighted magnetic resonance imaging. Pol J Radiol. 2019, 84:e142-6. 10.5114\/pjr.2019.84096","journal-title":"Pol J Radiol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2017.03.007","article-title":"Orbital decompression for thyroid eye disease","volume":"63","author":"Rootman DB","year":"2018","unstructured":"Rootman DB. Orbital decompression for thyroid eye disease. Surv Ophthalmol. 2018, 63:86-104. 10.1016\/j.survophthal.2017.03.007","journal-title":"Surv Ophthalmol"},{"key":"ref15","article-title":"MRI of thyroid ophthalmopathy: correlation with clinical and ophthalmologic findings","volume":"19","author":"Umehara I","year":"1995","unstructured":"Umehara I, Hoshino T, Ishii K, et al.. MRI of thyroid ophthalmopathy: correlation with clinical and ophthalmologic findings. J Comput Assist Tomogr. 1995, 19:274-9.","journal-title":"J Comput Assist Tomogr"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/427815-quantitative-magnetic-resonance-imaging-biomarkers-in-the-evaluation-of-disease-activity-in-thyroid-eye-disease-a-retrospective-study","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T12:44:52Z","timestamp":1767876292000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/427815-quantitative-magnetic-resonance-imaging-biomarkers-in-the-evaluation-of-disease-activity-in-thyroid-eye-disease-a-retrospective-study"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,8]]},"references-count":15,"URL":"https:\/\/doi.org\/10.7759\/cureus.101075","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1,8]]}}}