{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T19:15:42Z","timestamp":1768245342760,"version":"3.49.0"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,12]]},"DOI":"10.7759\/cureus.101366","type":"journal-article","created":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T15:46:46Z","timestamp":1768232806000},"source":"Crossref","is-referenced-by-count":0,"title":["Limb Salvage in Methicillin-Resistant Staphylococcus aureus (MRSA)-Complicated Necrotic Loxoscelism Through Lifotronic\u00ae Negative Pressure Wound Therapy and Wolfe\u2013McGregor Reconstruction"],"prefix":"10.7759","author":[{"given":"Christopher Kaleb","family":"Romero R\u00edos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaleb Mathias","family":"R\u00edos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Quintana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roderick","family":"Altamirano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aviezar","family":"Blandon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2004.08.028","article-title":"Loxoscelism: old obstacles, new directions","volume":"44","author":"Hogan CJ","year":"2004","unstructured":"Hogan CJ, Barbaro KC, Winkel K. Loxoscelism: old obstacles, new directions. Ann Emerg Med. 2004, 44:608-24. 10.1016\/j.annemergmed.2004.08.028","journal-title":"Ann Emerg Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-020-02719-0","article-title":"Clinical aspects, diagnosis and management of Loxosceles spider envenomation: literature and case review","volume":"94","author":"Lopes PH","year":"2020","unstructured":"Lopes PH, Squaiella-Baptist\u00e3o CC, Marques MO, Tambourgi DV. Clinical aspects, diagnosis and management of Loxosceles spider envenomation: literature and case review. Arch Toxicol. 2020, 94:1461-77. 10.1007\/s00204-020-02719-0","journal-title":"Arch Toxicol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2005.11.006","article-title":"Loxoscelism","volume":"24","author":"Swanson DL","year":"2006","unstructured":"Swanson DL, Vetter RS. Loxoscelism. Clin Dermatol. 2006, 24:213-21. 10.1016\/j.clindermatol.2005.11.006","journal-title":"Clin Dermatol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0000000000001086","article-title":"Community-acquired methicillin-resistant Staphylococcus aureus: is it still a significant pathogen for skin and soft tissue infections? A 30-year overview","volume":"38","author":"Burillo A","year":"2025","unstructured":"Burillo A, Bouza E. Community-acquired methicillin-resistant Staphylococcus aureus: is it still a significant pathogen for skin and soft tissue infections? A 30-year overview. Curr Opin Infect Dis. 2025, 38:78-91. 10.1097\/QCO.0000000000001086","journal-title":"Curr Opin Infect Dis"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra041184","article-title":"Bites of brown recluse spiders and suspected necrotic arachnidism","volume":"352","author":"Swanson DL","year":"2005","unstructured":"Swanson DL, Vetter RS. Bites of brown recluse spiders and suspected necrotic arachnidism. N Engl J Med. 2005, 352:700-7. 10.1056\/NEJMra041184","journal-title":"N Engl J Med"},{"key":"ref6","article-title":"Cutaneous loxoscelism mainly edematous, a case report (Article in Spanish)","author":"Barra P","year":"2015","unstructured":"Barra P, Vial V, Labra\u00f1a Y, \u00c1lvarez A, Seguel H. Cutaneous loxoscelism mainly edematous, a case report (Article in Spanish). Universidad de Chile. 2015,","journal-title":"Universidad de Chile"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1089\/sur.2011.101","article-title":"Risk factors for mixed complicated skin and skin structure infections to help tailor appropriate empiric therapy","volume":"13","author":"Zilberberg M","year":"2012","unstructured":"Zilberberg M, Micek ST, Kollef MH, Shelbaya A, Shorr AF. Risk factors for mixed complicated skin and skin structure infections to help tailor appropriate empiric therapy. Surg Infect (Larchmt). 2012, 13:377-82. 10.1089\/sur.2011.101","journal-title":"Surg Infect (Larchmt)"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciu296","article-title":"Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the infectious diseases society of America","volume":"59","author":"Stevens DL","year":"2014","unstructured":"Stevens DL, Bisno AL, Chambers HF, et al.. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the infectious diseases society of America. Clin Infect Dis. 2014, 59:147-59. 10.1093\/cid\/ciu296","journal-title":"Clin Infect Dis"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000002645","article-title":"Negative-pressure wound therapy: a comprehensive review of the evidence","volume":"138","author":"Anghel EL","year":"2016","unstructured":"Anghel EL, Kim PJ. Negative-pressure wound therapy: a comprehensive review of the evidence. Plast Reconstr Surg. 2016, 138:129S-37S. 10.1097\/PRS.0000000000002645","journal-title":"Plast Reconstr Surg"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD005083.pub4","article-title":"Honey as a topical treatment for wounds","volume":"2015","author":"Jull AB","year":"2015","unstructured":"Jull AB, Cullum N, Dumville JC, Westby MJ, Deshpande S, Walker N. Honey as a topical treatment for wounds. Cochrane Database Syst Rev. 2015, 2015:CD005083. 10.1002\/14651858.CD005083.pub4","journal-title":"Cochrane Database Syst Rev"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/437691-limb-salvage-in-methicillin-resistant-staphylococcus-aureus-mrsa-complicated-necrotic-loxoscelism-through-lifotronic-negative-pressure-wound-therapy-and-wolfe-mcgregor-reconstruction","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T15:46:47Z","timestamp":1768232807000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/437691-limb-salvage-in-methicillin-resistant-staphylococcus-aureus-mrsa-complicated-necrotic-loxoscelism-through-lifotronic-negative-pressure-wound-therapy-and-wolfe-mcgregor-reconstruction"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,12]]},"references-count":10,"URL":"https:\/\/doi.org\/10.7759\/cureus.101366","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1,12]]}}}