{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:31:45Z","timestamp":1791304305582,"version":"4.3.1"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,14]]},"DOI":"10.7759\/cureus.101513","type":"journal-article","created":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T12:23:26Z","timestamp":1768393406000},"source":"Crossref","is-referenced-by-count":2,"title":["Unexplained Acute Homonymous Hemianopia as a Presentation of Creutzfeldt-Jakob Disease"],"prefix":"10.7759","author":[{"given":"Omua","family":"Esezoobo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Gosal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KeiraAnnie","family":"Markey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2012-304820","article-title":"Intensity of human prion disease surveillance predicts observed disease incidence","volume":"84","author":"Klug GM","year":"2013","unstructured":"Klug GM, Wand H, Simpson M, et al.. Intensity of human prion disease surveillance predicts observed disease incidence. J Neurol Neurosurg Psychiatry. 2013, 84:1372-7. 10.1136\/jnnp-2012-304820","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-150668","article-title":"Revisiting the Heidenhain variant of Creutzfeldt-Jakob disease: evidence for prion type variability influencing clinical course and laboratory findings","volume":"50","author":"Baiardi S","year":"2016","unstructured":"Baiardi S, Capellari S, Ladogana A, Strumia S, Santangelo M, Pocchiari M, Parchi P. Revisiting the Heidenhain variant of Creutzfeldt-Jakob disease: evidence for prion type variability influencing clinical course and laboratory findings. J Alzheimers Dis. 2016, 50:465-76. 10.3233\/JAD-150668","journal-title":"J Alzheimers Dis"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.938654","article-title":"Heidenhain variant of sporadic Creutzfeldt-Jakob disease with a variety of visual symptoms: a case report with autopsy study","volume":"24","author":"Hisata Y","year":"2023","unstructured":"Hisata Y, Yamashita S, Tago M, et al.. Heidenhain variant of sporadic Creutzfeldt-Jakob disease with a variety of visual symptoms: a case report with autopsy study. Am J Case Rep. 2023, 24:e938654. 10.12659\/AJCR.938654","journal-title":"Am J Case Rep"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e31821a4439","article-title":"Diffusion-weighted MRI hyperintensity patterns differentiate CJD from other rapid dementias","volume":"76","author":"Vitali P","year":"2011","unstructured":"Vitali P, Maccagnano E, Caverzasi E, et al.. Diffusion-weighted MRI hyperintensity patterns differentiate CJD from other rapid dementias. Neurology. 2011, 76:1711-9. 10.1212\/WNL.0b013e31821a4439","journal-title":"Neurology"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9394(14)71237-1","article-title":"Homonymous field defect as the first manifestation of Creutzfeldt-Jakob disease","volume":"119","author":"Vargas ME","year":"1995","unstructured":"Vargas ME, Kupersmith MJ, Savino PJ, Petito F, Frohman LP, Warren FA. Homonymous field defect as the first manifestation of Creutzfeldt-Jakob disease. Am J Ophthalmol. 1995, 119:497-504. 10.1016\/s0002-9394(14)71237-1","journal-title":"Am J Ophthalmol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1444-0938.2006.00001.x","article-title":"Creutzfeldt-Jakob disease and vision","volume":"89","author":"Armstrong RA","year":"2006","unstructured":"Armstrong RA. Creutzfeldt-Jakob disease and vision. Clin Exp Optom. 2006, 89:3-9. 10.1111\/j.1444-0938.2006.00001.x","journal-title":"Clin Exp Optom"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2005.074856","article-title":"Isolated visual symptoms at onset in sporadic Creutzfeldt-Jakob disease: the clinical phenotype of the \"Heidenhain variant\"","volume":"89","author":"Cooper SA","year":"2005","unstructured":"Cooper SA, Murray KL, Heath CA, Will RG, Knight RS. Isolated visual symptoms at onset in sporadic Creutzfeldt-Jakob disease: the clinical phenotype of the \"Heidenhain variant\". Br J Ophthalmol. 2005, 89:1341-2. 10.1136\/bjo.2005.074856","journal-title":"Br J Ophthalmol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2000.76","article-title":"Creutzfeldt-Jakob disease and the eye. II. Ophthalmic and neuro-ophthalmic features","volume":"14","author":"Lueck CJ","year":"2000","unstructured":"Lueck CJ, McIlwaine GG, Zeidler M. Creutzfeldt-Jakob disease and the eye. II. Ophthalmic and neuro-ophthalmic features. Eye (Lond). 2000, 14:291-301. 10.1038\/eye.2000.76","journal-title":"Eye (Lond)"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/01.wno.0000235587.41040.39","article-title":"Homonymous hemianopia in stroke","volume":"26","author":"Zhang X","year":"2006","unstructured":"Zhang X, Kedar S, Lynn MJ, Newman NJ, Biousse V. Homonymous hemianopia in stroke. J Neuroophthalmol. 2006, 26:180-3. 10.1097\/01.wno.0000235587.41040.39","journal-title":"J Neuroophthalmol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2010.03.012","article-title":"Functional visual loss","volume":"28","author":"Bruce BB","year":"2010","unstructured":"Bruce BB, Newman NJ. Functional visual loss. Neurol Clin. 2010, 28:789-802. 10.1016\/j.ncl.2010.03.012","journal-title":"Neurol Clin"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1136\/practneurol-2016-001571","article-title":"CJD mimics and chameleons","volume":"17","author":"Mead S","year":"2017","unstructured":"Mead S, Rudge P. CJD mimics and chameleons. Pract Neurol. 2017, 17:113-21. 10.1136\/practneurol-2016-001571","journal-title":"Pract Neurol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awp191","article-title":"Updated clinical diagnostic criteria for sporadic Creutzfeldt-Jakob disease","volume":"132","author":"Zerr I","year":"2009","unstructured":"Zerr I, Kallenberg K, Summers DM, et al.. Updated clinical diagnostic criteria for sporadic Creutzfeldt-Jakob disease. Brain. 2009, 132:2659-68. 10.1093\/brain\/awp191","journal-title":"Brain"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-023-11962-1","article-title":"MRI abnormalities in Creutzfeldt-Jakob disease and other rapidly progressive dementia","volume":"271","author":"Manara R","year":"2024","unstructured":"Manara R, Fragiacomo F, Ladogana A, et al.. MRI abnormalities in Creutzfeldt-Jakob disease and other rapidly progressive dementia. J Neurol. 2024, 271:300-9. 10.1007\/s00415-023-11962-1","journal-title":"J Neurol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2005.12.007","article-title":"EEG in Creutzfeldt-Jakob disease","volume":"117","author":"Wieser HG","year":"2006","unstructured":"Wieser HG, Schindler K, Zumsteg D. EEG in Creutzfeldt-Jakob disease. Clin Neurophysiol. 2006, 117:935-51. 10.1016\/j.clinph.2005.12.007","journal-title":"Clin Neurophysiol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111\/ene.15380","article-title":"Clinical and prognostic features of Heidenhain variant of Creutzfeldt-Jakob disease: a retrospective case series study","volume":"29","author":"Yang SL","year":"2022","unstructured":"Yang SL, Zhang LY, Zhang SF, et al.. Clinical and prognostic features of Heidenhain variant of Creutzfeldt-Jakob disease: a retrospective case series study. Eur J Neurol. 2022, 29:2412-9. 10.1111\/ene.15380","journal-title":"Eur J Neurol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(20)30477-4","article-title":"Biomarkers and diagnostic guidelines for sporadic Creutzfeldt-Jakob disease","volume":"20","author":"Hermann P","year":"2021","unstructured":"Hermann P, Appleby B, Brandel JP, et al.. Biomarkers and diagnostic guidelines for sporadic Creutzfeldt-Jakob disease. Lancet Neurol. 2021, 20:235-46. 10.1016\/S1474-4422(20)30477-4","journal-title":"Lancet Neurol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-10922-w","article-title":"High diagnostic value of second generation CSF RT-QuIC across the wide spectrum of CJD prions","volume":"7","author":"Franceschini A","year":"2017","unstructured":"Franceschini A, Baiardi S, Hughson AG, et al.. High diagnostic value of second generation CSF RT-QuIC across the wide spectrum of CJD prions. Sci Rep. 2017, 7:10655. 10.1038\/s41598-017-10922-w","journal-title":"Sci Rep"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/438337-unexplained-acute-homonymous-hemianopia-as-a-presentation-of-creutzfeldt-jakob-disease","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T12:23:26Z","timestamp":1768393406000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/438337-unexplained-acute-homonymous-hemianopia-as-a-presentation-of-creutzfeldt-jakob-disease"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,14]]},"references-count":17,"URL":"https:\/\/doi.org\/10.7759\/cureus.101513","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1,14]]}}}