{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T11:25:15Z","timestamp":1768476315641,"version":"3.49.0"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,14]]},"DOI":"10.7759\/cureus.101553","type":"journal-article","created":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T22:34:12Z","timestamp":1768430052000},"source":"Crossref","is-referenced-by-count":0,"title":["Priapism as an Initial Presentation of Sickle Cell Disease: A Case Report"],"prefix":"10.7759","author":[{"given":"Serkalem G","family":"Abebe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Constance","family":"Cleveland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maya","family":"Kohavi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saba","family":"Zafar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brandon","family":"Yanik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ucl.2007.08.006","article-title":"Priapism: current principles and practice","volume":"34","author":"Burnett AL","year":"2007","unstructured":"Burnett AL, Bivalacqua TJ. Priapism: current principles and practice. Urol Clin North Am. 2007, 34:631-642, viii. 10.1016\/j.ucl.2007.08.006","journal-title":"Urol Clin North Am"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1743-6109.2011.02317.x","article-title":"Priapism and sickle-cell anemia: diagnosis and nonsurgical therapy","volume":"9","author":"Broderick GA","year":"2012","unstructured":"Broderick GA. Priapism and sickle-cell anemia: diagnosis and nonsurgical therapy. J Sex Med. 2012, 9:88-103. 10.1111\/j.1743-6109.2011.02317.x","journal-title":"J Sex Med"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/JU.0000000000002754","article-title":"Pediatric urology","volume":"208","author":"Canning DA","year":"2022","unstructured":"Canning DA. Pediatric urology. J Urol. 2022, 208:461-462. 10.1097\/JU.0000000000002754","journal-title":"J Urol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1182\/hematology.2022000380","article-title":"Epidemiology and treatment of priapism in sickle cell disease","volume":"2022","author":"Idris IM","year":"2022","unstructured":"Idris IM, Burnett AL, DeBaun MR. Epidemiology and treatment of priapism in sickle cell disease. Hematology Am Soc Hematol Educ Program. 2022, 2022:450-458. 10.1182\/hematology.2022000380","journal-title":"Hematology Am Soc Hematol Educ Program"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1510865","article-title":"Sickle cell disease","volume":"376","author":"Piel FB","year":"2017","unstructured":"Piel FB, Steinberg MH, Rees DC. Sickle cell disease. N Engl J Med. 2017, 376:1561-1573. 10.1056\/NEJMra1510865","journal-title":"N Engl J Med"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(23)00160-6","article-title":"Prevalence, years lived with disability, and trends in anaemia burden by severity and cause, 1990-2021: findings from the Global Burden of Disease Study 2021","volume":"10","author":"GBD 2021 Anaemia Collaborators","year":"2023","unstructured":"GBD 2021 Anaemia Collaborators. Prevalence, years lived with disability, and trends in anaemia burden by severity and cause, 1990-2021: findings from the Global Burden of Disease Study 2021. Lancet Haematol. 2023, 10:e713-e734. 10.1016\/S2352-3026(23)00160-6","journal-title":"Lancet Haematol"},{"key":"ref7","unstructured":"Centers for Disease Control and Prevention. Data & statistics on sickle cell disease. (2023). Accessed. January 13, 2026: https:\/\/www.cdc.gov\/sickle-cell\/index.html."},{"key":"ref8","article-title":"Impact of expanded newborn screening\u2014United States, 2006","volume":"57","author":"Centers for Disease Control and Prevention (CDC)","year":"2008","unstructured":"Centers for Disease Control and Prevention (CDC). Impact of expanded newborn screening\u2014United States, 2006. MMWR Morb Mortal Wkly Rep. 2008, 57:1009-1032.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2015.03.008","article-title":"Newborn screening for sickle cell diseases in the United States: a review of data spanning 2 decades","volume":"39","author":"Therrell BL Jr","year":"2015","unstructured":"Therrell BL Jr, Lloyd-Puryear MA, Eckman JR, Mann MY. Newborn screening for sickle cell diseases in the United States: a review of data spanning 2 decades. Semin Perinatol. 2015, 39:238-251. 10.1053\/j.semperi.2015.03.008","journal-title":"Semin Perinatol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2024.1435220","article-title":"Targeting heme in sickle cell disease: new perspectives on priapism treatment","volume":"15","author":"Silveira TH","year":"2024","unstructured":"Silveira TH, Calmasini FB, de Oliveira MG, Costa FF, Silva FH. Targeting heme in sickle cell disease: new perspectives on priapism treatment. Front Physiol. 2024, 15:1435220. 10.3389\/fphys.2024.1435220","journal-title":"Front Physiol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0246067","article-title":"Priapism in sickle cell disease: associations between NOS3 and EDN1 genetic polymorphisms and laboratory biomarkers","volume":"16","author":"Figueiredo CV","year":"2021","unstructured":"Figueiredo CV, Santiago RP, da Guarda CC, et al.. Priapism in sickle cell disease: associations between NOS3 and EDN1 genetic polymorphisms and laboratory biomarkers. PLoS One. 2021, 16:e0246067. 10.1371\/journal.pone.0246067","journal-title":"PLoS One"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/jsm.12816","article-title":"Erectile dysfunction after sickle cell disease-associated recurrent ischemic priapism: profile and risk factors","volume":"12","author":"Anele UA","year":"2015","unstructured":"Anele UA, Burnett AL. Erectile dysfunction after sickle cell disease-associated recurrent ischemic priapism: profile and risk factors. J Sex Med. 2015, 12:713-719. 10.1111\/jsm.12816","journal-title":"J Sex Med"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2020002062","article-title":"Men with sickle cell disease experience greater sexual dysfunction when compared with men without sickle cell disease","volume":"4","author":"Idris IM","year":"2020","unstructured":"Idris IM, Abba A, Galadanci JA, et al.. Men with sickle cell disease experience greater sexual dysfunction when compared with men without sickle cell disease. Blood Adv. 2020, 4:3277-3283. 10.1182\/bloodadvances.2020002062","journal-title":"Blood Adv"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0258560","article-title":"External validation of the priapism impact profile in a Jamaican cohort of patients with sickle cell disease","volume":"16","author":"Morrison BF","year":"2021","unstructured":"Morrison BF, Madden W, Asnani M, et al.. External validation of the priapism impact profile in a Jamaican cohort of patients with sickle cell disease. PLoS One. 2021, 16:e0258560. 10.1371\/journal.pone.0258560","journal-title":"PLoS One"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.14393","article-title":"Regular automated red cell exchange transfusion in the management of stuttering priapism complicating sickle cell disease","volume":"180","author":"Ekong A","year":"2018","unstructured":"Ekong A, Berg L, Amos RJ, Tsitsikas DA. Regular automated red cell exchange transfusion in the management of stuttering priapism complicating sickle cell disease. Br J Haematol. 2018, 180:585-588. 10.1111\/bjh.14393","journal-title":"Br J Haematol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2023012083","article-title":"Evaluating self- vs interviewer-administered screening for depression in sickle cell disease","volume":"8","author":"Lysandrou M","year":"2024","unstructured":"Lysandrou M, Quaye N, Landes K, et al.. Evaluating self- vs interviewer-administered screening for depression in sickle cell disease. Blood Adv. 2024, 8:699-702. 10.1182\/bloodadvances.2023012083","journal-title":"Blood Adv"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD004198.pub4","article-title":"Treatments for priapism in boys and men with sickle cell disease","volume":"4","author":"Chinegwundoh FI","year":"2020","unstructured":"Chinegwundoh FI, Smith S, Anie KA. Treatments for priapism in boys and men with sickle cell disease. Cochrane Database Syst Rev. 2020, 4:CD004198. 10.1002\/14651858.CD004198.pub4","journal-title":"Cochrane Database Syst Rev"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2024027898","article-title":"A controlled trial for preventing priapism in sickle cell anemia: hydroxyurea plus placebo vs hydroxyurea plus tadalafil","volume":"145","author":"Idris IM","year":"2025","unstructured":"Idris IM, Yusuf AA, Ismail II, et al.. A controlled trial for preventing priapism in sickle cell anemia: hydroxyurea plus placebo vs hydroxyurea plus tadalafil. Blood. 2025, 145:3101-3112. 10.1182\/blood.2024027898","journal-title":"Blood"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/448785-priapism-as-an-initial-presentation-of-sickle-cell-disease-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T22:34:13Z","timestamp":1768430053000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/448785-priapism-as-an-initial-presentation-of-sickle-cell-disease-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,14]]},"references-count":18,"URL":"https:\/\/doi.org\/10.7759\/cureus.101553","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1,14]]}}}