{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T05:16:44Z","timestamp":1768540604972,"version":"3.49.0"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,15]]},"DOI":"10.7759\/cureus.101590","type":"journal-article","created":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T12:49:43Z","timestamp":1768481383000},"source":"Crossref","is-referenced-by-count":0,"title":["A Digital Patient Engagement and Monitoring System to Improve Quality, Safety, and Continuity of Care for Pediatric Sickle Cell Anemia: A Cross-Sectional Study of Caregiver Perceptions"],"prefix":"10.7759","author":[{"given":"Ehab","family":"Hanafy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Badriah G","family":"Alasmari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdelhakam A","family":"Elmugadam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara S","family":"Hassanien","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayman S","family":"Alsafy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed","family":"Alpakra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1510865","article-title":"Sickle cell disease","volume":"376","author":"Piel FB","year":"2017","unstructured":"Piel FB, Steinberg MH, Rees DC. Sickle cell disease. N Engl J Med. 2017, 376:1561-73. 10.1056\/NEJMra1510865","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.378","article-title":"Acute care utilization and rehospitalizations for sickle cell disease","volume":"303","author":"Brousseau DC","year":"2010","unstructured":"Brousseau DC, Owens PL, Mosso AL, Panepinto JA, Steiner CA. Acute care utilization and rehospitalizations for sickle cell disease. JAMA. 2010, 303:1288-94. 10.1001\/jama.2010.378","journal-title":"JAMA"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-0177","article-title":"Medication adherence among pediatric patients with sickle cell disease: a systematic review","volume":"134","author":"Walsh KE","year":"2014","unstructured":"Walsh KE, Cutrona SL, Kavanagh PL, Crosby LE, Malone C, Lobner K, Bundy DG. Medication adherence among pediatric patients with sickle cell disease: a systematic review. Pediatrics. 2014, 134:1175-83. 10.1542\/peds.2014-0177","journal-title":"Pediatrics"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2009.10.035","article-title":"Treatment adherence in patients with sickle cell anemia","volume":"156","author":"Drotar D","year":"2010","unstructured":"Drotar D. Treatment adherence in patients with sickle cell anemia. J Pediatr. 2010, 156:350-1. 10.1016\/j.jpeds.2009.10.035","journal-title":"J Pediatr"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001362","article-title":"The effectiveness of mobile-health technology-based health behaviour change or disease management interventions for health care consumers: a systematic review","volume":"10","author":"Free C","year":"2013","unstructured":"Free C, Phillips G, Galli L, et al.. The effectiveness of mobile-health technology-based health behaviour change or disease management interventions for health care consumers: a systematic review. PLoS Med. 2013, 10:e1001362. 10.1371\/journal.pmed.1001362","journal-title":"PLoS Med"},{"key":"ref6","article-title":"Global Strategy on Digital Health 2020-2025","author":"World Health Organization","year":"2021","unstructured":"World Health Organization. Global Strategy on Digital Health 2020-2025. World Health Organization, Geneva; 2021."},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.2196\/jmir.3951","article-title":"Impact of mHealth chronic disease management on treatment adherence and patient outcomes: a systematic review","volume":"17","author":"Hamine S","year":"2015","unstructured":"Hamine S, Gerth-Guyette E, Faulx D, Green BB, Ginsburg AS. Impact of mHealth chronic disease management on treatment adherence and patient outcomes: a systematic review. J Med Internet Res. 2015, 17:e52. 10.2196\/jmir.3951","journal-title":"J Med Internet Res"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.2196\/mhealth.7798","article-title":"Text messaging and mobile phone apps as interventions to improve adherence in adolescents with chronic health conditions: a systematic review","volume":"5","author":"Badawy SM","year":"2017","unstructured":"Badawy SM, Barrera L, Sinno MG, Kaviany S, O'Dwyer LC, Kuhns LM. Text messaging and mobile phone apps as interventions to improve adherence in adolescents with chronic health conditions: a systematic review. JMIR Mhealth Uhealth. 2017, 5:e66. 10.2196\/mhealth.7798","journal-title":"JMIR Mhealth Uhealth"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.2196\/mhealth.6742","article-title":"Mobile phone apps to improve medication adherence: a systematic stepwise process to identify high-quality apps","volume":"4","author":"Santo K","year":"2016","unstructured":"Santo K, Richtering SS, Chalmers J, Thiagalingam A, Chow CK, Redfern J. Mobile phone apps to improve medication adherence: a systematic stepwise process to identify high-quality apps. JMIR Mhealth Uhealth. 2016, 4:e132. 10.2196\/mhealth.6742","journal-title":"JMIR Mhealth Uhealth"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2023010670","article-title":"A multilevel mHealth intervention boosts adherence to hydroxyurea in individuals with sickle cell disease","volume":"7","author":"Hankins JS","year":"2023","unstructured":"Hankins JS, Brambilla D, Potter MB, et al.. A multilevel mHealth intervention boosts adherence to hydroxyurea in individuals with sickle cell disease. Blood Adv. 2023, 7:7190-201. 10.1182\/bloodadvances.2023010670","journal-title":"Blood Adv"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.26177","article-title":"Development and evaluation of iManage: A self-management app co-designed by adolescents with sickle cell disease","volume":"64","author":"Crosby LE","year":"2017","unstructured":"Crosby LE, Ware RE, Goldstein A, Walton A, Joffe NE, Vogel C, Britto MT. Development and evaluation of iManage: A self-management app co-designed by adolescents with sickle cell disease. Pediatr Blood Cancer. 2017, 64:139-45. 10.1002\/pbc.26177","journal-title":"Pediatr Blood Cancer"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.2196\/jmir.6731","article-title":"Social health inequalities and e health: a literature review with qualitative synthesis of theoretical and empirical studies","volume":"19","author":"Latulippe K","year":"2017","unstructured":"Latulippe K, Hamel C, Giroux D. Social health inequalities and e health: a literature review with qualitative synthesis of theoretical and empirical studies. J Med Internet Res. 2017, 19:e136. 10.2196\/jmir.6731","journal-title":"J Med Internet Res"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1186\/s12911-016-0359-3","article-title":"Understanding factors affecting patient and public engagement and recruitment to digital health interventions: a systematic review of qualitative studies","volume":"16","author":"O'Connor S","year":"2016","unstructured":"O'Connor S, Hanlon P, O'Donnell CA, Garcia S, Glanville J, Mair FS. Understanding factors affecting patient and public engagement and recruitment to digital health interventions: a systematic review of qualitative studies. BMC Med Inform Decis Mak. 2016, 16:120. 10.1186\/s12911-016-0359-3","journal-title":"BMC Med Inform Decis Mak"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.2196\/10235","article-title":"Factors determining the success and failure of eHealth interventions: systematic review of the literature","volume":"20","author":"Granja C","year":"2018","unstructured":"Granja C, Janssen W, Johansen MA. Factors determining the success and failure of eHealth interventions: systematic review of the literature. J Med Internet Res. 2018, 20:e10235. 10.2196\/10235","journal-title":"J Med Internet Res"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.7189\/jogh.10.020396","article-title":"Factors influencing the sustainability of digital health interventions in low-resource settings: lessons from five countries","volume":"10","author":"McCool J","year":"2020","unstructured":"McCool J, Dobson R, Muinga N, et al.. Factors influencing the sustainability of digital health interventions in low-resource settings: lessons from five countries. J Glob Health. 2020, 10:020396. 10.7189\/jogh.10.020396","journal-title":"J Glob Health"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1093\/jamia\/ocv052","article-title":"m-Health adoption by healthcare professionals: a systematic review","volume":"23","author":"Gagnon MP","year":"2016","unstructured":"Gagnon MP, Ngangue P, Payne-Gagnon J, Desmartis M. m-Health adoption by healthcare professionals: a systematic review. J Am Med Inform Assoc. 2016, 23:212-20. 10.1093\/jamia\/ocv052","journal-title":"J Am Med Inform Assoc"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.2196\/10940","article-title":"Patient-centered eHealth interventions for children, adolescents, and adults with sickle cell disease: systematic review","volume":"20","author":"Badawy SM","year":"2018","unstructured":"Badawy SM, Cronin RM, Hankins J, Crosby L, DeBaun M, Thompson AA, Shah N. Patient-centered eHealth interventions for children, adolescents, and adults with sickle cell disease: systematic review. J Med Internet Res. 2018, 20:e10940. 10.2196\/10940","journal-title":"J Med Internet Res"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/445506-a-digital-patient-engagement-and-monitoring-system-to-improve-quality-safety-and-continuity-of-care-for-pediatric-sickle-cell-anemia-a-cross-sectional-study-of-caregiver-perceptions","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T12:49:44Z","timestamp":1768481384000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/445506-a-digital-patient-engagement-and-monitoring-system-to-improve-quality-safety-and-continuity-of-care-for-pediatric-sickle-cell-anemia-a-cross-sectional-study-of-caregiver-perceptions"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,15]]},"references-count":17,"URL":"https:\/\/doi.org\/10.7759\/cureus.101590","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1,15]]}}}