{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T12:51:55Z","timestamp":1792587115260,"version":"4.5.0"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,18]]},"DOI":"10.7759\/cureus.101796","type":"journal-article","created":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T21:32:20Z","timestamp":1768771940000},"source":"Crossref","is-referenced-by-count":5,"title":["Active Craniospinal Tensioning (ACT): Axial Spinal Traction for Glymphatic Modulation"],"prefix":"10.7759","author":[{"given":"Huan-Wei","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00031.2020","article-title":"Fluid transport in the brain","volume":"102","author":"Rasmussen MK","year":"2022","unstructured":"Rasmussen MK, Mestre H, Nedergaard M. Fluid transport in the brain. Physiol Rev. 2022, 102:1025-151. 10.1152\/physrev.00031.2020","journal-title":"Physiol Rev"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.92341","article-title":"Sustained bulbar and respiratory function in a case most consistent with bulbar-onset amyotrophic lateral sclerosis following axial spinal traction: a 21-month report","volume":"17","author":"Chen HW","year":"2025","unstructured":"Chen HW. Sustained bulbar and respiratory function in a case most consistent with bulbar-onset amyotrophic lateral sclerosis following axial spinal traction: a 21-month report. Cureus. 2025, 17:e92341. 10.7759\/cureus.92341","journal-title":"Cureus"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.99153","article-title":"Axial spinal traction as a potential modulator of cerebrospinal and glymphatic circulation in neurodegenerative diseases: a technical report and biomechanical hypothesis","volume":"17","author":"Chen HW","year":"2025","unstructured":"Chen HW. Axial spinal traction as a potential modulator of cerebrospinal and glymphatic circulation in neurodegenerative diseases: a technical report and biomechanical hypothesis. Cureus. 2025, 17:e99153. 10.7759\/cureus.99153","journal-title":"Cureus"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.4236\/jbbs.2021.1110019","article-title":"Dura mater: anatomy and clinical implication","volume":"11","author":"\u00dcnal M","year":"2021","unstructured":"\u00dcnal M, Sezgin A. Dura mater: anatomy and clinical implication. J Behav Brain Sci. 2021, 11:10. 10.4236\/jbbs.2021.1110019","journal-title":"J Behav Brain Sci"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2019.09.085","article-title":"Neuropsychological decline up to 20\u00a0years before incident mild cognitive impairment","volume":"16","author":"Caselli RJ","year":"2020","unstructured":"Caselli RJ, Langlais BT, Dueck AC, et al.. Neuropsychological decline up to 20\u00a0years before incident mild cognitive impairment. Alzheimers Dement. 2020, 16:512-23. 10.1016\/j.jalz.2019.09.085","journal-title":"Alzheimers Dement"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s11604-017-0617-z","article-title":"Evaluation of glymphatic system activity with the diffusion MR technique: diffusion tensor image analysis along the perivascular space (DTI-ALPS) in Alzheimer's disease cases","volume":"35","author":"Taoka T","year":"2017","unstructured":"Taoka T, Masutani Y, Kawai H, et al.. Evaluation of glymphatic system activity with the diffusion MR technique: diffusion tensor image analysis along the perivascular space (DTI-ALPS) in Alzheimer's disease cases. Jpn J Radiol. 2017, 35:172-8. 10.1007\/s11604-017-0617-z","journal-title":"Jpn J Radiol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.2463\/mrms.rev.2020-0122","article-title":"The glymphatic system: a review of the challenges in visualizing its structure and function with MR imaging","volume":"21","author":"Naganawa S","year":"2022","unstructured":"Naganawa S, Taoka T. The glymphatic system: a review of the challenges in visualizing its structure and function with MR imaging. Magn Reson Med Sci. 2022, 21:182-94. 10.2463\/mrms.rev.2020-0122","journal-title":"Magn Reson Med Sci"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-025-01151-4","article-title":"A systematic review and meta-analysis on glymphatic flow dysfunction in Parkinson's disease and Parkinsonism spectrum","volume":"11","author":"Ghaderi S","year":"2025","unstructured":"Ghaderi S, Mohammadi S, Jouzdani AF, Ahmadzadeh AM, Fatehi F. A systematic review and meta-analysis on glymphatic flow dysfunction in Parkinson's disease and Parkinsonism spectrum. NPJ Parkinsons Dis. 2025, 11:306. 10.1038\/s41531-025-01151-4","journal-title":"NPJ Parkinsons Dis"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awad274","article-title":"Glymphatic dysfunction in patients with early-stage amyotrophic lateral sclerosis","volume":"147","author":"Liu S","year":"2024","unstructured":"Liu S, Sun X, Ren Q, et al.. Glymphatic dysfunction in patients with early-stage amyotrophic lateral sclerosis. Brain. 2024, 147:100-8. 10.1093\/brain\/awad274","journal-title":"Brain"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/mds.30194","article-title":"Diffusion along perivascular spaces as a marker for glymphatic system impairment in Huntington's disease","volume":"40","author":"Yin JH","year":"2025","unstructured":"Yin JH, Cao LX, Liu YO, Huang Y. Diffusion along perivascular spaces as a marker for glymphatic system impairment in Huntington's disease. Mov Disord. 2025, 40:1409-19. 10.1002\/mds.30194","journal-title":"Mov Disord"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.21037\/qims-24-510","article-title":"Glymphatic function assessment with diffusion tensor imaging along the perivascular space in patients with major depressive disorder and its relation to cerebral white-matter alteration","volume":"14","author":"Yang C","year":"2024","unstructured":"Yang C, Tian S, Du W, et al.. Glymphatic function assessment with diffusion tensor imaging along the perivascular space in patients with major depressive disorder and its relation to cerebral white-matter alteration. Quant Imaging Med Surg. 2024, 14:6397-412. 10.21037\/qims-24-510","journal-title":"Quant Imaging Med Surg"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2024.08.094","article-title":"Unveiling the link between glymphatic function and cortical microstructures in post-traumatic stress disorder","volume":"365","author":"Shao Z","year":"2024","unstructured":"Shao Z, Gao X, Cen S, Tang X, Gong J, Ding W. Unveiling the link between glymphatic function and cortical microstructures in post-traumatic stress disorder. J Affect Disord. 2024, 365:341-50. 10.1016\/j.jad.2024.08.094","journal-title":"J Affect Disord"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2024.10.008","article-title":"Investigating DTI-ALPS index and its association with cognitive impairments in patients with alcohol use disorder: a diffusion tensor imaging study","volume":"180","author":"Dai X","year":"2024","unstructured":"Dai X, Gao L, Zhang J, et al.. Investigating DTI-ALPS index and its association with cognitive impairments in patients with alcohol use disorder: a diffusion tensor imaging study. J Psychiatr Res. 2024, 180:213-8. 10.1016\/j.jpsychires.2024.10.008","journal-title":"J Psychiatr Res"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci13091292","article-title":"Glymphatic-system function is associated with addiction and relapse in heroin dependents undergoing methadone maintenance treatment","volume":"13","author":"Wang L","year":"2023","unstructured":"Wang L, Qin Y, Li X, Li X, Liu Y, Li W, Wang Y. Glymphatic-system function is associated with addiction and relapse in heroin dependents undergoing methadone maintenance treatment. Brain Sci. 2023, 13:16-8. 10.3390\/brainsci13091292","journal-title":"Brain Sci"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A8215","article-title":"Reduced diffusivity along perivascular spaces on MR imaging associated with younger age of first use and cognitive impairment in recreational marijuana users","volume":"45","author":"Andica C","year":"2024","unstructured":"Andica C, Kamagata K, Takabayashi K, Mahemuti Z, Hagiwara A, Aoki S. Reduced diffusivity along perivascular spaces on MR imaging associated with younger age of first use and cognitive impairment in recreational marijuana users. AJNR Am J Neuroradiol. 2024, 45:912-9. 10.3174\/ajnr.A8215","journal-title":"AJNR Am J Neuroradiol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1177\/13524585241280842","article-title":"Glymphatic dysfunction in multiple sclerosis and its association with disease pathology and disability","volume":"30","author":"Bayoumi A","year":"2024","unstructured":"Bayoumi A, Hasan KM, Thomas JA, Yazdani A, Lincoln JA. Glymphatic dysfunction in multiple sclerosis and its association with disease pathology and disability. Mult Scler. 2024, 30:1609-19. 10.1177\/13524585241280842","journal-title":"Mult Scler"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keae251","article-title":"Glymphatic abnormality in systemic lupus erythematosus detected by diffusion tensor image analysis along the perivascular space","volume":"64","author":"Mo J","year":"2025","unstructured":"Mo J, Han K, Deng K, et al.. Glymphatic abnormality in systemic lupus erythematosus detected by diffusion tensor image analysis along the perivascular space. Rheumatology (Oxford). 2025, 64:1210-9. 10.1093\/rheumatology\/keae251","journal-title":"Rheumatology (Oxford)"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2025.1701816","article-title":"Glymphatic system dysfunction in children with autism spectrum disorder as evidenced by the diffusion tensor imaging along perivascular spaces index","volume":"16","author":"Zhao S","year":"2025","unstructured":"Zhao S, Zhang M, Luo T, Li L, Jiang Y, Situ M, Huang Y. Glymphatic system dysfunction in children with autism spectrum disorder as evidenced by the diffusion tensor imaging along perivascular spaces index. Front Psychiatry. 2025, 16:1701816. 10.3389\/fpsyt.2025.1701816","journal-title":"Front Psychiatry"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2025.03.059","article-title":"Glymphatic system dysfunction in adult ADHD: relationship to cognitive performance","volume":"379","author":"Fang Y","year":"2025","unstructured":"Fang Y, Peng J, Chu T, Gao F, Xiong F, Tu Y. Glymphatic system dysfunction in adult ADHD: relationship to cognitive performance. J Affect Disord. 2025, 379:150-8. 10.1016\/j.jad.2025.03.059","journal-title":"J Affect Disord"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/444322-active-craniospinal-tensioning-act-axial-spinal-traction-for-glymphatic-modulation","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T21:32:20Z","timestamp":1768771940000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/444322-active-craniospinal-tensioning-act-axial-spinal-traction-for-glymphatic-modulation"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,18]]},"references-count":19,"URL":"https:\/\/doi.org\/10.7759\/cureus.101796","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1,18]]}}}