{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T05:27:11Z","timestamp":1769059631489,"version":"3.49.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,21]]},"DOI":"10.7759\/cureus.101988","type":"journal-article","created":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T14:02:08Z","timestamp":1769004128000},"source":"Crossref","is-referenced-by-count":0,"title":["Nocardia farcinica Brain Abscess Mimicking Acute Ischemic Stroke in an Immunocompetent Elderly Patient: A Case Report"],"prefix":"10.7759","author":[{"given":"In\u00eas","family":"Fi\u00faza M. Rua","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00e9rgio","family":"Caba\u00e7o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diogo D","family":"Ramos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lilian C","family":"Farias","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Margarida","family":"Serrano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2017.07.033","article-title":"Nocardia farcinica brain abscess: Report of 3 cases","volume":"106","author":"Galacho-Harriero A","year":"2017","unstructured":"Galacho-Harriero A, Delgado-L\u00f3pez PD, Ortega-Lafont MP, Mart\u00edn-Alonso J, Castilla-D\u00edez JM, S\u00e1nchez-Borge B. Nocardia farcinica brain abscess: Report of 3 cases. World Neurosurg. 2017, 106:1053.e15-24. 10.1016\/j.wneu.2017.07.033","journal-title":"World Neurosurg"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000005255","article-title":"Central nervous system nocardiosis in Queensland: A report of 20 cases and review of the literature","volume":"95","author":"Rafiei N","year":"2016","unstructured":"Rafiei N, Peri AM, Righi E, Harris P, Paterson DL. Central nervous system nocardiosis in Queensland: A report of 20 cases and review of the literature. Medicine (Baltimore). 2016, 95:e5255. 10.1097\/MD.0000000000005255","journal-title":"Medicine (Baltimore)"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2007.01078.x","article-title":"Pulmonary nocardiosis: Risk factors and outcomes","volume":"12","author":"Mart\u00ednez Tom\u00e1s R","year":"2007","unstructured":"Mart\u00ednez Tom\u00e1s R, Men\u00e9ndez Villanueva R, Reyes Calzada S, Santos Durantez M, Vall\u00e9s Tarazona JM, Modesto Alapont M, Gobernado Serrano M. Pulmonary nocardiosis: Risk factors and outcomes. Respirology. 2007, 12:394-400. 10.1111\/j.1440-1843.2007.01078.x","journal-title":"Respirology"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0303-8467(01)00201-3","article-title":"Primary brain abscess with Nocardia farcinica in an immunocompetent patient","volume":"104","author":"Malincarne L","year":"2002","unstructured":"Malincarne L, Marroni M, Farina C, et al.. Primary brain abscess with Nocardia farcinica in an immunocompetent patient. Clin Neurol Neurosurg. 2002, 104:132-5. 10.1016\/S0303-8467(01)00201-3","journal-title":"Clin Neurol Neurosurg"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.7.2.213","article-title":"Nocardia species: Host-parasite relationships","volume":"7","author":"Beaman BL","year":"1994","unstructured":"Beaman BL, Beaman L. Nocardia species: Host-parasite relationships. Clin Microbiol Rev. 1994, 7:213-64. 10.1128\/CMR.7.2.213","journal-title":"Clin Microbiol Rev"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S1201-9712(03)90102-0","article-title":"Nocardiosis: A review","volume":"7","author":"Corti ME","year":"2003","unstructured":"Corti ME, Fioti MF. Nocardiosis: A review. Int J Infect Dis. 2003, 7:243-50. 10.1016\/S1201-9712(03)90102-0","journal-title":"Int J Infect Dis"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-009-9193-9","article-title":"Nocardiosis: Updated clinical review and experience at a tertiary center","volume":"38","author":"Ambrosioni J","year":"2010","unstructured":"Ambrosioni J, Lew D, Garbino J. Nocardiosis: Updated clinical review and experience at a tertiary center. Infection. 2010, 38:89-97. 10.1007\/s15010-009-9193-9","journal-title":"Infection"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2025.116954","article-title":"Successful management of Nocardia farcinica brain abscess in an immunocompetent adult with trimethoprim\/sulfamethoxazole hypersensitivity: A case report and review","volume":"113","author":"Hong WL","year":"2025","unstructured":"Hong WL, Yao LY, Zhong Z, Meng FJ, Zhang WY, Lu K, She ZY. Successful management of Nocardia farcinica brain abscess in an immunocompetent adult with trimethoprim\/sulfamethoxazole hypersensitivity: A case report and review. Diagn Microbiol Infect Dis. 2025, 113:116954. 10.1016\/j.diagmicrobio.2025.116954","journal-title":"Diagn Microbiol Infect Dis"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1089\/sur.2012.205","article-title":"Nocardia farcinica brain abscess: Epidemiology, pathophysiology, and literature review","volume":"15","author":"Kumar VA","year":"2014","unstructured":"Kumar VA, Augustine D, Panikar D, Nandakumar A, Dinesh KR, Karim S, Philip R. Nocardia farcinica brain abscess: Epidemiology, pathophysiology, and literature review. Surg Infect (Larchmt). 2014, 15:640-6. 10.1089\/sur.2012.205","journal-title":"Surg Infect (Larchmt)"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000039019","article-title":"Multiple brain abscesses caused by Nocardia farcinica infection after hand injury: A case report and literature review","volume":"103","author":"Xue K","year":"2024","unstructured":"Xue K, Zhang A, Liu S, Chen D. Multiple brain abscesses caused by Nocardia farcinica infection after hand injury: A case report and literature review. Medicine (Baltimore). 2024, 103:e39019. 10.1097\/MD.0000000000039019","journal-title":"Medicine (Baltimore)"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2020.12.019","article-title":"How do I manage nocardiosis?","volume":"27","author":"Margalit I","year":"2021","unstructured":"Margalit I, Lebeaux D, Tishler O, Goldberg E, Bishara J, Yahav D, Coussement J. How do I manage nocardiosis?. Clin Microbiol Infect. 2021, 27:550-8. 10.1016\/j.cmi.2020.12.019","journal-title":"Clin Microbiol Infect"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2022.05.029","article-title":"Prognosis and factors associated with disseminated nocardiosis: A ten-year multicenter study","volume":"85","author":"Soueges S","year":"2022","unstructured":"Soueges S, Bouiller K, Botelho-Nevers E, et al.. Prognosis and factors associated with disseminated nocardiosis: A ten-year multicenter study. J Infect. 2022, 85:130-6. 10.1016\/j.jinf.2022.05.029","journal-title":"J Infect"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2024.107147","article-title":"Multicenter systematic review of clinical characteristics, diagnostic optimization, and personalized treatment for brain Nocardia infections","volume":"198","author":"Shen J","year":"2025","unstructured":"Shen J, Du B, Liu Z, Song Z, Yuan M, Qiu X, Li Z. Multicenter systematic review of clinical characteristics, diagnostic optimization, and personalized treatment for brain Nocardia infections. Microb Pathog. 2025, 198:107147. 10.1016\/j.micpath.2024.107147","journal-title":"Microb Pathog"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2025.1687102","article-title":"Nocardia infection: A rare case report of a cerebellar mass","volume":"12","author":"Azaharuddin I","year":"2025","unstructured":"Azaharuddin I, Mokhtar MN, Ding CH, Azmi MI, Abdullah FH, Su YP, Zainudin A. Nocardia infection: A rare case report of a cerebellar mass. Front Med (Lausanne). 2025, 12:1687102. 10.3389\/fmed.2025.1687102","journal-title":"Front Med (Lausanne)"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1080\/20009666.2021.1877399","article-title":"Brain metastasis or nocardiosis? A case report of central nervous system Nocardiosis with a review of the literature","volume":"11","author":"Sun H","year":"2021","unstructured":"Sun H, Goolam Mahomed M, Patel J. Brain metastasis or nocardiosis? A case report of central nervous system Nocardiosis with a review of the literature. J Community Hosp Intern Med Perspect. 2021, 11:258-62. 10.1080\/20009666.2021.1877399","journal-title":"J Community Hosp Intern Med Perspect"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1159\/000525509","article-title":"Clinical characteristics and treatment outcome of central nervous system Nocardiosis: A systematic review of reported cases","volume":"31","author":"Meena DS","year":"2022","unstructured":"Meena DS, Kumar D, Bohra GK, Midha N, Garg MK. Clinical characteristics and treatment outcome of central nervous system Nocardiosis: A systematic review of reported cases. Med Princ Pract. 2022, 31:333-41. 10.1159\/000525509","journal-title":"Med Princ Pract"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1186\/s40001-021-00562-2","article-title":"A case report of brain abscess caused by Nocardia farcinica","volume":"26","author":"Song J","year":"2021","unstructured":"Song J, Dong L, Ding Y, Zhou J. A case report of brain abscess caused by Nocardia farcinica. Eur J Med Res. 2021, 26:83. 10.1186\/s40001-021-00562-2","journal-title":"Eur J Med Res"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-024-02445-0","article-title":"Shorter vs. standard-duration antibiotic therapy for nocardiosis: A multi-center retrospective cohort study","volume":"53","author":"Attias NH","year":"2025","unstructured":"Attias NH, Schlaeffer-Yosef T, Zahavi I, et al.. Shorter vs. standard-duration antibiotic therapy for nocardiosis: A multi-center retrospective cohort study. Infection. 2025, 53:1115-27. 10.1007\/s15010-024-02445-0","journal-title":"Infection"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiac.2024.04.008","article-title":"Successful maintenance treatment of disseminated nocardiosis with cerebral abscess in a severely immunocompromised patient allergic to trimethoprim-sulfamethoxazole using moxifloxacin and high-dose minocycline: A case report","volume":"30","author":"Yamamoto H","year":"2024","unstructured":"Yamamoto H, Kuroda H, Hiramoto N, Hasuike T, Doi A, Nishioka H. Successful maintenance treatment of disseminated nocardiosis with cerebral abscess in a severely immunocompromised patient allergic to trimethoprim-sulfamethoxazole using moxifloxacin and high-dose minocycline: A case report. J Infect Chemother. 2024, 30:1319-23. 10.1016\/j.jiac.2024.04.008","journal-title":"J Infect Chemother"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2023.02.023","article-title":"Clinical characteristics, susceptibility profiles, and treatment of nocardiosis: A multicenter retrospective study in 2015-2021","volume":"130","author":"Yang J","year":"2023","unstructured":"Yang J, Ren HT, Wang J, et al.. Clinical characteristics, susceptibility profiles, and treatment of nocardiosis: A multicenter retrospective study in 2015-2021. Int J Infect Dis. 2023, 130:136-43. 10.1016\/j.ijid.2023.02.023","journal-title":"Int J Infect Dis"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/455749-nocardia-farcinica-brain-abscess-mimicking-acute-ischemic-stroke-in-an-immunocompetent-elderly-patient-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T14:02:09Z","timestamp":1769004129000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/455749-nocardia-farcinica-brain-abscess-mimicking-acute-ischemic-stroke-in-an-immunocompetent-elderly-patient-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,21]]},"references-count":20,"URL":"https:\/\/doi.org\/10.7759\/cureus.101988","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1,21]]}}}