{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T07:21:36Z","timestamp":1769239296042,"version":"3.49.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,22]]},"DOI":"10.7759\/cureus.102059","type":"journal-article","created":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T11:51:54Z","timestamp":1769082714000},"source":"Crossref","is-referenced-by-count":0,"title":["Complete Mesocolic Excision Compared With Conventional Right Hemicolectomy for Colorectal Cancer Outcomes: A Systematic Review and Meta-Analysis of Observational Cohorts"],"prefix":"10.7759","author":[{"given":"Imran Gul","family":"Shiekh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hafiz Muhammad","family":"Ijaz Ul Haq","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Syed Hasan","family":"Raza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21834","article-title":"Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"74","author":"Bray F","year":"2024","unstructured":"Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, Jemal A. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2024, 74:229-63. 10.3322\/caac.21834","journal-title":"CA Cancer J Clin"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.23.1860","article-title":"Practical application of a calculator for conditional survival in colon cancer","volume":"27","author":"Chang GJ","year":"2009","unstructured":"Chang GJ, Hu CY, Eng C, Skibber JM, Rodriguez-Bigas MA. Practical application of a calculator for conditional survival in colon cancer. J Clin Oncol. 2009, 27:5938-43. 10.1200\/JCO.2009.23.1860","journal-title":"J Clin Oncol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-021-08683-9","article-title":"Distinctive features of small vessels on the mesorectal and parietal pelvic fascia as important landmarks in guiding precise inter-fascial dissection for low rectal cancer","volume":"36","author":"Wu Q","year":"2022","unstructured":"Wu Q, Wei M, Zhang X, Deng X, Wang Z. Distinctive features of small vessels on the mesorectal and parietal pelvic fascia as important landmarks in guiding precise inter-fascial dissection for low rectal cancer. Surg Endosc. 2022, 36:1657-65. 10.1007\/s00464-021-08683-9","journal-title":"Surg Endosc"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2015.09.047","article-title":"Total mesorectal excision, an erroneous anatomical term for the gold standard in rectal cancer treatment","volume":"23","author":"Rodr\u00edguez-Luna MR","year":"2015","unstructured":"Rodr\u00edguez-Luna MR, Guarneros-Z\u00e1rate JE, Tueme-Izaguirre J. Total mesorectal excision, an erroneous anatomical term for the gold standard in rectal cancer treatment. Int J Surg. 2015, 23:97-100. 10.1016\/j.ijsu.2015.09.047","journal-title":"Int J Surg"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2008.01735.x","article-title":"Standardized surgery for colonic cancer: complete mesocolic excision and central ligation--technical notes and outcome","volume":"11","author":"Hohenberger W","year":"2009","unstructured":"Hohenberger W, Weber K, Matzel K, Papadopoulos T, Merkel S. Standardized surgery for colonic cancer: complete mesocolic excision and central ligation--technical notes and outcome. Colorectal Dis. 2009, 11:354-64. 10.1111\/j.1463-1318.2008.01735.x","journal-title":"Colorectal Dis"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-019-06869-w","article-title":"The fusion fascia of Fredet: an important embryological landmark for complete mesocolic excision and D3-lymphadenectomy in right colon cancer","volume":"33","author":"Garcia-Granero A","year":"2019","unstructured":"Garcia-Granero A, Pellino G, Frasson M, et al.. The fusion fascia of Fredet: an important embryological landmark for complete mesocolic excision and D3-lymphadenectomy in right colon cancer. Surg Endosc. 2019, 33:3842-50. 10.1007\/s00464-019-06869-w","journal-title":"Surg Endosc"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.asjsur.2018.11.006","article-title":"The Toldt fascia: a historic review and surgical implications in complete mesocolic excision for colon cancer","volume":"42","author":"Liang JT","year":"2019","unstructured":"Liang JT, Huang J, Chen TC, Hung JS. The Toldt fascia: a historic review and surgical implications in complete mesocolic excision for colon cancer. Asian J Surg. 2019, 42:1-5. 10.1016\/j.asjsur.2018.11.006","journal-title":"Asian J Surg"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-013-1818-2","article-title":"The rationale behind complete mesocolic excision (CME) and a central vascular ligation for colon cancer in open and laparoscopic surgery : proceedings of a consensus conference","volume":"29","author":"S\u00f8ndenaa K","year":"2014","unstructured":"S\u00f8ndenaa K, Quirke P, Hohenberger W, et al.. The rationale behind complete mesocolic excision (CME) and a central vascular ligation for colon cancer in open and laparoscopic surgery : proceedings of a consensus conference. Int J Colorectal Dis. 2014, 29:419-28. 10.1007\/s00384-013-1818-2","journal-title":"Int J Colorectal Dis"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-021-10186-9","article-title":"Complete mesocolic excision and D3 lymphadenectomy versus conventional colectomy for colon cancer: a systematic review and meta-analysis","volume":"28","author":"D\u00edaz-Vico T","year":"2021","unstructured":"D\u00edaz-Vico T, Fern\u00e1ndez-Hevia M, Su\u00e1rez-S\u00e1nchez A, et al.. Complete mesocolic excision and D3 lymphadenectomy versus conventional colectomy for colon cancer: a systematic review and meta-analysis. Ann Surg Oncol. 2021, 28:8823-37. 10.1245\/s10434-021-10186-9","journal-title":"Ann Surg Oncol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3393\/ac.2020.05.18","article-title":"Comparison of short-term results after laparoscopic complete mesocolic excision and standard colectomy for right-sided colon cancer: analysis of a Western center cohort","volume":"37","author":"Conti C","year":"2021","unstructured":"Conti C, Pedrazzani C, Turri G, et al.. Comparison of short-term results after laparoscopic complete mesocolic excision and standard colectomy for right-sided colon cancer: analysis of a Western center cohort. Ann Coloproctol. 2021, 37:166-73. 10.3393\/ac.2020.05.18","journal-title":"Ann Coloproctol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.2147\/CMAR.S203150","article-title":"Comparison of outcomes of complete mesocolic excision with conventional radical resection performed by laparoscopic approach for right colon cancer","volume":"11","author":"Ouyang M","year":"2019","unstructured":"Ouyang M, Luo Z, Wu J, et al.. Comparison of outcomes of complete mesocolic excision with conventional radical resection performed by laparoscopic approach for right colon cancer. Cancer Manag Res. 2019, 11:8647-56. 10.2147\/CMAR.S203150","journal-title":"Cancer Manag Res"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.84369","article-title":"Comparative evaluation of complete mesocolic excision versus conventional right hemicolectomy in right-sided colon cancer: a retrospective observational study","volume":"17","author":"Kadirvel D","year":"2025","unstructured":"Kadirvel D, Ganesan S, Parthasarathy I, V GK, K G M. Comparative evaluation of complete mesocolic excision versus conventional right hemicolectomy in right-sided colon cancer: a retrospective observational study. Cureus. 2025, 17:e84369. 10.7759\/cureus.84369","journal-title":"Cureus"},{"key":"ref13","article-title":"Complete mesocolic excision versus conventional right colectomy: a comparative single-centre study","volume":"79","author":"Mydin SHM","year":"2024","unstructured":"Mydin SHM. Complete mesocolic excision versus conventional right colectomy: a comparative single-centre study. Med J Malaysia. 2024, 79:326-32.","journal-title":"Med J Malaysia"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s10353-023-00804-z","article-title":"Comparison of conventional right colectomy and complete mesocolic excision technique: case-control analysis of short-term results","volume":"55","author":"Sztipits T","year":"2023","unstructured":"Sztipits T. Comparison of conventional right colectomy and complete mesocolic excision technique: case-control analysis of short-term results. Eur Surg. 2023, 55:70-8. 10.1007\/s10353-023-00804-z","journal-title":"Eur Surg"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.4274\/tjcd.galenos.2020.2020-8-4","article-title":"Is complete mesocolic excision technique superior to conventional hemicolectomy for right-sided colon cancer?","volume":"30","author":"T\u00fcmay LV","year":"2020","unstructured":"T\u00fcmay LV. Is complete mesocolic excision technique superior to conventional hemicolectomy for right-sided colon cancer?. Turk J Colorectal Dis. 2020, 30:301-10. 10.4274\/tjcd.galenos.2020.2020-8-4","journal-title":"Turk J Colorectal Dis"},{"key":"ref16","article-title":"The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Nonrandomised Studies in Meta-Analyses","author":"Wells GA","year":"2011","unstructured":"Wells GA, Shea B, O\u2019Connell D, et al.. The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Nonrandomised Studies in Meta-Analyses. Ottawa Hospital Research Institute, Ottawa, Canada; 2011."},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111\/codi.15644","article-title":"Complete mesocolic excision versus conventional surgery for colon cancer: a systematic review and meta-analysis","volume":"23","author":"Crane J","year":"2021","unstructured":"Crane J, Hamed M, Borucki JP, El-Hadi A, Shaikh I, Stearns AT. Complete mesocolic excision versus conventional surgery for colon cancer: a systematic review and meta-analysis. Colorectal Dis. 2021, 23:1670-86. 10.1111\/codi.15644","journal-title":"Colorectal Dis"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1177\/15533506211060230","article-title":"D3 versus D2 lymphadenectomy in right hemicolectomy: a systematic review and meta-analysis","volume":"29","author":"Liu S","year":"2022","unstructured":"Liu S, Li L, Sun H, Chen B, Yu M, Zhong M. D3 versus D2 lymphadenectomy in right hemicolectomy: a systematic review and meta-analysis. Surg Innov. 2022, 29:416-25. 10.1177\/15533506211060230","journal-title":"Surg Innov"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1111\/ans.16518","article-title":"Oncological reasons for performing a complete mesocolic excision: a systematic review and meta-analysis","volume":"91","author":"Kong JC","year":"2021","unstructured":"Kong JC, Prabhakaran S, Choy KT, Larach JT, Heriot A, Warrier SK. Oncological reasons for performing a complete mesocolic excision: a systematic review and meta-analysis. ANZ J Surg. 2021, 91:124-31. 10.1111\/ans.16518","journal-title":"ANZ J Surg"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l4898","article-title":"RoB 2: a revised tool for assessing risk of bias in randomised trials","volume":"366","author":"Sterne JA","year":"2019","unstructured":"Sterne JA, Savovi\u0107 J, Page MJ, et al.. RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ. 2019, 366:l4898. 10.1136\/bmj.l4898","journal-title":"BMJ"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i4919","article-title":"ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions","volume":"355","author":"Sterne JA","year":"2016","unstructured":"Sterne JA, Hern\u00e1n MA, Reeves BC, et al.. ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ. 2016, 355:i4919. 10.1136\/bmj.i4919","journal-title":"BMJ"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-14-135","article-title":"Estimating the sample mean and standard deviation from the sample size, median, range and\/or interquartile range","volume":"14","author":"Wan X","year":"2014","unstructured":"Wan X, Wang W, Liu J, Tong T. Estimating the sample mean and standard deviation from the sample size, median, range and\/or interquartile range. BMC Med Res Methodol. 2014, 14:135. 10.1186\/1471-2288-14-135","journal-title":"BMC Med Res Methodol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/451904-complete-mesocolic-excision-compared-with-conventional-right-hemicolectomy-for-colorectal-cancer-outcomes-a-systematic-review-and-meta-analysis-of-observational-cohorts","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T11:51:58Z","timestamp":1769082718000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/451904-complete-mesocolic-excision-compared-with-conventional-right-hemicolectomy-for-colorectal-cancer-outcomes-a-systematic-review-and-meta-analysis-of-observational-cohorts"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,22]]},"references-count":22,"URL":"https:\/\/doi.org\/10.7759\/cureus.102059","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1,22]]}}}